Results 31 to 40 of about 5,517,395 (407)

Structure-activity relationship in monosaccharide-based Toll-like receptor 4 (TLR4) antagonists [PDF]

, 2018
The structure-activity relationship was investigated in a series of synthetic TLR4 antagonists formed by a glucosamine core linked to two phosphate esters and two linear carbon chains.
Airoldi, Cristina, Beyaert, Rudi, Billod, Jean-Marc, Braun, Harald, Calabrese, Valentina, Ciaramelli, Carlotta, Facchini, Fabio A, Forcella, Matilde, Fusi, Paola, Jerala, Roman, Lapenta, Fabio, Martin-Santamaria, Sonsoles, Minotti, Alberto, Palmer, Charys, Peri, Francesco, Pirianov, Grisha, Rapisarda, Silvia, Schromm, Andra B, Zaffaroni, Lenny   +18 more
core   +3 more sources

Antibacterial Properties of Polyphenols: Characterization and QSAR (Quantitative Structure–Activity Relationship) Models

Frontiers in Microbiology, 2019
Besides their established antioxidant activity, many phenolic compounds may exhibit significant antibacterial activity. Here, the effect of a large dataset of 35 polyphenols on the growth of 6 foodborne pathogenic or food-spoiling bacterial strains ...
Lynda Bouarab-Chibane, V. Forquet, P. Lanteri, Y. Clément, Lucie Léonard-Akkari, N. Oulahal, P. Degraeve, C. Bordes   +7 more
semanticscholar   +1 more source

Identification of Six Flavonoids as Novel Cellular Antioxidants and Their Structure-Activity Relationship

Oxidative Medicine and Cellular Longevity, 2020
This study is aimed at determining the relationship of flavonoid structures to their chemical and intracellular antioxidant activities. The antioxidant activities of 60 flavonoids were investigated by three different antioxidant assays, including 2,2 ...
Qiang Zhang, Wenbo Yang, Jiechao Liu, Hui Liu, Zhenzhen Lv, Chunling Zhang, Dalei Chen, Zhonggao Jiao   +7 more
semanticscholar   +1 more source

Investigating the Structure–Activity Relationship of the Insecticidal Natural Product Rocaglamide

CHIMIA, 2017
The natural product Rocaglamide (1), isolated from the tree Aglaia elliptifolia, is a compelling but also challenging lead structure for crop protection.
Roger G. Hall, Ian Bruce, Nigel G. Cooke, Louis J. Diorazio, Fredrik Cederbaum, Markus R. Dobler, Ed Irving   +6 more
doaj   +1 more source

Design, Synthesis, and Anti-Inflammatory Activities of 12-Dehydropyxinol Derivatives

Molecules, 2023
Pyxinol skeleton is a promising framework of anti-inflammatory agents formed in the human liver from 20S-protopanaxadiol, the main active aglycone of ginsenosides. In the present study, a new series of amino acid-containing derivatives were produced from
Yunxiao Wang, Xiaoliang Mi, Yuan Du, Shuang Li, Liping Yu, Meng Gao, Xiaoyue Yang, Zhihua Song, Hui Yu, Gangqiang Yang   +9 more
doaj   +1 more source

Structure-activity relationships of estrogens.

Environmental Health Perspectives, 1985
The last 50 years has seen an exponential rise in the published reports about estrogen action. The model to describe the early events in the mechanism of action of estrogens via the estrogen receptor is updated in this paper to incorporate some of the recent data on the subcellular localization of the receptor.
M. E. Lieberman, Virgil Craig Jordan, R. Koch, B Gosden, S. Mittal   +4 more
openaire   +3 more sources

Electrochemical behavior of indolone-N-oxides: Relationship to structure and antiplasmodial activity [PDF]

, 2012
Indolone-N-oxides exert high parasiticidal activity at the nanomolar level in vitro against Plasmodiumfalciparum, the parasite responsible for malaria.
Fabre, Paul-Louis, Ibrahim, Hany, Montrose, Armelle, Nepveu, Françoise, Nguyen, Thi Hoang Yen, Perio, Pierre, Reybier, Karine   +6 more
core   +3 more sources

Synthesis and Fungicidal Activity of β-Carboline Alkaloids and Their Derivatives

Molecules, 2015
A series of β-Carboline derivatives were designed, synthesized, and evaluated for their fungicidal activities in this study. Several derivatives electively exhibited fungicidal activities against some fungi.
Zhibin Li, Shaohua Chen, Shaowen Zhu, Jianjun Luo, Yaomou Zhang, Qunfang Weng   +5 more
doaj   +1 more source

Biosynthesis, chemical structure, and structure-activity relationship of orfamide lipopeptides produced by Pseudomonas protegens and related species [PDF]

, 2016
Orfamide type cyclic lipopeptides (CLPs) are biosurfactants produced by Pseudomonas and involved in lysis of oomycete zoospores, biocontrol of Rhizoctonia and insecticidal activity against aphids.
Geudens, Niels, Höfte, Monica, Kieu Phuong, Nam, Ma, Zongwang, Martins, José, Ongena, Marc, Sinnaeve, Davy   +6 more
core   +3 more sources

Synthesis and Antibacterial Evaluation of N-phenylacetamide Derivatives Containing 4-Arylthiazole Moieties

Molecules, 2020
A series of new N-phenylacetamide derivatives containing 4-arylthiazole moieties was designed and synthesized by introducing the thiazole moiety into the amide scaffold.
Hui Lu, Xia Zhou, Lei Wang, Linhong Jin
doaj   +1 more source