Results 31 to 40 of about 5,731,059 (238)

An Insight into Antihyperlipidemic Effects of Polysaccharides from Natural Resources

Molecules, 2022
Hyperlipidemia is a chronic metabolic disease caused by the abnormal metabolism of lipoproteins in the human body. Its main hazard is to accelerate systemic atherosclerosis, which causes cerebrovascular diseases such as coronary heart disease and ...
Yong-Shuai Jing, Yun-Feng Ma, Fei-Bing Pan, Ming-Song Li, Yu-Guang Zheng, Lan-Fang Wu, Dan-Shen Zhang   +6 more
doaj   +1 more source

Second-generation nitazoxanide derivatives: thiazolides are effective inhibitors of the influenza A virus [PDF]

, 2018
Aim: The only small molecule drugs currently available for treatment of influenza A virus (IAV) are M2 ion channel blockers and sialidase inhibitors. The prototype thiazolide, nitazoxanide, has successfully completed Phase III clinical trials against ...
Andrew V Stachulski, Brian M Eklov, Chandrakala Pidathala, Eleanor C Row, Giuseppe Belardo, J Edward Semple, Jean-Francois Rossignol, La Frazia S, M Gabriella Santoro, Mazhar Iqbal, Neil G Berry, Paul M O'Neill, Podlogar BL, Rossignol JF, Rossignol JF, Sara Piacentini, Sarah A Allman, Simone La Frazia   +17 more
core   +1 more source

Structure-antioxidant activity relationship of methoxy, phenolic hydroxyl, and carboxylic acid groups of phenolic acids

Scientific Reports, 2020
The antioxidant activities of 18 typical phenolic acids were investigated using 2, 2′-diphenyl-1-picrylhydrazyl (DPPH) and ferric ion reducing antioxidant power (FRAP) assays.
Jinxiang Chen, Jing Yang, Lanlan Ma, Jun Li, Nasir Shahzad, Chan Kyung Kim   +5 more
semanticscholar   +1 more source

Improvement of the Oxidative Stability of Rosehip, Hemp, and Passion Fruit Oils by the Addition of Monocyclic Phenols as Antioxidants

Antioxidants
Caffeic, syringic, and protocatechuic acids are phenolic acids with important antioxidant activity. In this work we studied how the oxidative stability of rosehip, hemp, and passion fruit oils improves with the addition of these antioxidant acids.
Gloria Castellano, Irene Sarrión, Carmen Fagoaga, Ricardo M. Giménez-Núñez, Enrique Gómez-Gómez, Francisco Torrens   +5 more
doaj   +1 more source

Extended Functional Groups (EFG): An Efficient Set for Chemical Characterization and Structure-Activity Relationship Studies of Chemical Compounds

Molecules, 2015
The article describes a classification system termed “extended functional groups” (EFG), which are an extension of a set previously used by the CheckMol software, that covers in addition heterocyclic compound classes and periodic table groups.
Elena S. Salmina, N. Haider, I. Tetko
semanticscholar   +1 more source

Flavonoids as inhibitors of human neutrophil elastase

Journal of Enzyme Inhibition and Medicinal Chemistry, 2021
Elastase is a proteolytic enzyme belonging to the family of hydrolases produced by human neutrophils, monocytes, macrophages, and endothelial cells.
Katarzyna Jakimiuk, Jakub Gesek, Atanas G. Atanasov, Michał Tomczyk   +3 more
doaj   +1 more source

Clique topology reveals intrinsic geometric structure in neural correlations [PDF]

, 2015
Detecting meaningful structure in neural activity and connectivity data is challenging in the presence of hidden nonlinearities, where traditional eigenvalue-based methods may be misleading. We introduce a novel approach to matrix analysis, called clique
Curto, Carina, Giusti, Chad, Itskov, Vladimir, Pastalkova, Eva   +3 more
core   +3 more sources

Separation of Oligosaccharides from Lotus Seeds via Medium-pressure Liquid Chromatography Coupled with ELSD and DAD [PDF]

, 2017
peer-reviewedLotus seeds were identified by the Ministry of Public Health of China as both food and medicine. One general function of lotus seeds is to improve intestinal health.
AD Orozco-Cortes, BA Olsen, C Huang, D Feria-Gervasio, D García-Gómez, E Borch, FLY Fong, G Yen, H Kaplan, H Wang, J Li, J Valette, J Yang, Jh Wang, K Nimptsch, M Björklund, M Björklund, M Fernández, M Lv, MT Machado, O Bañuelos, P Hemström, P Weber, PK Mukherjee, R Tabasco, S Challal, S Gusakova, S Wu, T Ignatova, T Ikegami, TCMV Do, W Oleszek, W Zong, X Lu, X Lu, Y García-Curbelo, Y Zhang, YF Zheng, Z Guo, Z Yang   +39 more
core   +1 more source

Designing a Dual GLP-1R/GIPR Agonist from Tirzepatide: Comparing Residues Between Tirzepatide, GLP-1, and GIP

Drug Design, Development and Therapy, 2022
Lijing Wang College of Life Sciences and Technology, China Pharmaceutical University, Nanjing, Jiangsu, People’s Republic of ChinaCorrespondence: Lijing Wang, College of Life Science and Technology, China Pharmaceutical University, 639 Longmian ...
Wang L
doaj  

Spatially resolved electrochemistry in ionic liquids : surface structure effects on triiodide reduction at platinum electrodes [PDF]

, 2014
Understanding the relationship between electrochemical activity and electrode structure is vital for improving the efficiency of dye-sensitized solar cells.
Aaronson, Barak D. B., Lai, Stanley Chi Shing, Unwin, Patrick R.   +2 more
core   +2 more sources