Oxidative Medicine and Cellular Longevity, 2020 This study is aimed at determining the relationship of flavonoid structures to their chemical and intracellular antioxidant activities. The antioxidant activities of 60 flavonoids were investigated by three different antioxidant assays, including 2,2 ...
Qiang Zhang +7 more
semanticscholar +1 more source
Electrochemical behavior of indolone-N-oxides: Relationship to structure and antiplasmodial activity [PDF]
, 2012 Indolone-N-oxides exert high parasiticidal activity at the nanomolar level in vitro against Plasmodiumfalciparum, the parasite responsible for malaria.
Fabre, Paul-Louis +6 more
core +3 more sources
Investigating the Structure–Activity Relationship of the Insecticidal Natural Product Rocaglamide
CHIMIA, 2017 The natural product Rocaglamide (1), isolated from the tree Aglaia elliptifolia, is a compelling but also challenging lead structure for crop protection.
Roger G. Hall +6 more
doaj +1 more source
Structure-activity relationships of estrogens.
Environmental Health Perspectives, 1985 The last 50 years has seen an exponential rise in the published reports about estrogen action. The model to describe the early events in the mechanism of action of estrogens via the estrogen receptor is updated in this paper to incorporate some of the recent data on the subcellular localization of the receptor.
M. E. Lieberman +4 more
openaire +3 more sources
Biosynthesis, chemical structure, and structure-activity relationship of orfamide lipopeptides produced by Pseudomonas protegens and related species [PDF]
, 2016 Orfamide type cyclic lipopeptides (CLPs) are biosurfactants produced by Pseudomonas and involved in lysis of oomycete zoospores, biocontrol of Rhizoctonia and insecticidal activity against aphids.
Geudens, Niels +6 more
core +3 more sources
Synthesis and Fungicidal Activity of β-Carboline Alkaloids and Their Derivatives
Molecules, 2015 A series of β-Carboline derivatives were designed, synthesized, and evaluated for their fungicidal activities in this study. Several derivatives electively exhibited fungicidal activities against some fungi.
Zhibin Li +5 more
doaj +1 more source
Application of Hansch’s Model to Capsaicinoids and Capsinoids: A Study Using the Quantitative Structure−Activity Relationship. A Novel Method for the Synthesis of Capsinoids [PDF]
, 2010 We describe a synthetic approach for two families of compounds, the capsaicinoids and capsinoids, as part of a study of the quantitative relationship between structure and ...
Appendino G. +32 more
core +2 more sources
Journal of Enzyme Inhibition and Medicinal Chemistry, 2021 Inflammation and disease are closely related. Inflammation can induce various diseases, and diseases can promote inflammatory response, and two possibly induces each other in a bidirectional loop.
Ming Bian +4 more
doaj +1 more source
Vitamin K catabolite inhibition of ovariectomy-induced bone loss: Structure–activity relationship considerations [PDF]
, 2014 The potential benefit of vitamin K as a therapeutic in osteoporosis is controversial and the vitamin K regimen being used clinically (45 mg/day) employs doses that are many times higher than required to ensure maximal gamma‐carboxylation of the vitamin K‐
Emery, R +5 more
core +1 more source
Molecules, 2020 A series of new N-phenylacetamide derivatives containing 4-arylthiazole moieties was designed and synthesized by introducing the thiazole moiety into the amide scaffold.
Hui Lu, Xia Zhou, Lei Wang, Linhong Jin
doaj +1 more source