Results 81 to 90 of about 22,404,851 (343)
Advanced ScienceEfficient deuterium separation from hydrogen isotopic mixtures poses a significant challenge due to the nearly identical physicochemical properties of D2 and H2.
Zhuozhou Xie +11 more
doaj +1 more source
Molecules, 2018 Eukaryotic transcription initiation is mediated by interactions between transcriptional activators and the mediator coactivator complex. Molecular interaction of p53 transcription factor with mediator complex subunit 25 (MED25) is essential for its ...
Min-Sung Lee +3 more
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SWISS-MODEL: modelling protein tertiary and quaternary structure using evolutionary information
Nucleic Acids Res., 2014 Protein structure homology modelling has become a routine technique to generate 3D models for proteins when experimental structures are not available. Fully automated servers such as SWISS-MODEL with user-friendly web interfaces generate reliable models ...
M. Biasini +10 more
semanticscholar +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Flexural behavior of RC beams strengthened with CFRP sheets and ECC layers
Discover Applied SciencesTo further enhance the flexural capacity and ductility of reinforced concrete (RC) beams, this study proposes an innovative strengthening method. This approach, referred to as Carbon Fiber Reinforced Polymer (CFRP) and Engineered Cementitious Composite ...
Xiaobing Hou +9 more
doaj +1 more source
Cognitive Sciences, 1990 Time underlies many interesting human behaviors. Thus, the question of how to represent time in connectionist models is very important. One approach is to represent time implicitly by its effects on processing rather than explicitly (as in a spatial ...
J. Elman
semanticscholar +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Discover Applied SciencesRecycled fine aggregates (RFA), as a recyclable and reusable material, can help reduce the exploitation of natural resources and promote resource recycling.
Yanfen Gong +12 more
doaj +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Scientific ReportsA share-point is a cutting edge of the ploughshare, the crucial component of a horizontally reversible plough (HRP). Our previous trials in sandy loam soil indicated that severe abrasion/attrition wear with white materials appeared at the share-point ...
Yan-Chen Li +6 more
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