Results 21 to 30 of about 41,018 (241)

Ion-Pair Compounds of Strychnine for Enhancing Skin Permeability: Influencing the Transdermal Processes In Vitro Based on Molecular Simulation

open access: yesPharmaceuticals, 2021
This research aimed to explore how Strychnine (Str) ion-pair compounds affect the in vitro transdermal process. In order to prevent the influence of different functional groups on skin permeation, seven homologous fatty acids were selected to form ion ...
Lili He   +7 more
doaj   +1 more source

Phosphocholine-Modified Lipooligosaccharides of Haemophilus influenzae Inhibit ATP-Induced IL-1beta Release by Pulmonary Epithelial Cells [PDF]

open access: yes, 2018
Phosphocholine-modified bacterial cell wall components are virulence factors enabling immune evasion and permanent colonization of the mammalian host, by mechanisms that are poorly understood.
Grau, Veronika   +11 more
core   +1 more source

Simultaneous HPTLC determination of strychnine and brucine in strychnos nux-vomica seed

open access: yesJournal of Pharmacy and Bioallied Sciences, 2012
Objective: A simple, sensitive, and specific thin layer chromatography (TLC) densitometry method has been developed for the simultaneous quantification of strychnine and brucine in the seeds of Strychnos nux-vomica.
Abid Kamal   +4 more
doaj   +1 more source

The Usefulness of MS3 to Confirm Poisoning on the Example of Dog Poisoning with Strychnine

open access: yesMolecules, 2019
Strychnine is an alkaloid with strong toxic properties. Poisoning results in muscular contractions and death through asphyxiation. Intentional or accidental poisonings with strychnine occur mainly in small animals, especially dogs and occasionally cats ...
Tomasz Śniegocki   +2 more
doaj   +1 more source

Evaluation of antiepileptic activity of the methanol extract of Trachyspermum ammi (L.) [PDF]

open access: yesArchives of Biological Sciences, 2013
This study aims to investigate the effect of a methanol extract of Trachyspermum ammi (L.) as an antiepileptic agent. Tests were conducted with a single- and multiple-dosing schedule of Trachyspermum ammi (L.), using a strychnine-induced seizure model
Rajput Muhammad Ali   +2 more
doaj   +1 more source

The anodic oxidation of bases in the solvent m-cresol [PDF]

open access: yes, 1974
The oxidation of bases in the solvent m-cresol was investigated by polarography, voltammetry at the rotating platinum disc electrode and by chronopotentiometry. It was shown that the m-cresolate ion is the electroactive species in this reaction.
Bos, M., Dahmen, E.A.M.F.
core   +2 more sources

Serotonin drives a novel GABAergic synaptic current recorded in rat cerebellar purkinje cells: a lugaro cell to Purkinje cell synapse [PDF]

open access: yes, 2003
We recorded a novel fast GABAergic synaptic current in cerebellar Purkinje cells in rat brain slices using patch-clamp techniques. Because of a relatively low sensitivity to bicuculline, these currents can be recorded under conditions in which basket ...
Dean, I., Edwards, F.A., Robertson, S.J.
core   +3 more sources

Acid-Sensing Ion Channels Activated by Evoked Released Protons Modulate Synaptic Transmission at the Mouse Calyx of Held Synapse [PDF]

open access: yes, 2017
Acid-sensing ion channels (ASICs) regulate synaptic activities and play important roles in neurodegenerative diseases. We found that these channels can be activated in neurons of the medial nucleus of the trapezoid body (MNTB) of the auditory system in ...
Di Guilmi, Mariano Nicolás   +3 more
core   +1 more source

The Production and Evaluation of an Electrochemical Sensors for Strychnine and Its Main Metabolite Strychnine N-Oxide for Their Use in Biological Samples

open access: yesMolecules, 2022
Strychnine (STN) and its major metabolite Strychnine N-Oxide (SNO) were examined electrochemically. Both parent compounds and its major metabolite showed electroactivity on glassy carbon electrodes using CV and DPV techniques.
Bakhtiyar Qader   +5 more
doaj   +1 more source

Development of GABAergic and glycinergic transmission in the neonatal rat dorsal horn [PDF]

open access: yes, 2004
Cutaneous spinal sensory transmission appears to lack inhibitory control in the newborn spinal cord, but the properties of GABAergic and glycinergic synapses in the neonatal dorsal horn have not been characterized.
Baccei, ML, Fitzgerald, M
core   +1 more source

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