The sympathoregulatory region of the mouse rostral brainstem relies on both GABA and glycine to generate inhibitory currents. [PDF]
J PhysiolAbstract figure legend Our study demonstrates that both GABA and glycine mediate inhibitory postsynaptic currents in the ventrolateral/ventromedial medulla (VLM/VMM) and increasing the activity of inhibitory synapses facilitates glycine release. We found that presympathetic VLM/VMM neurons receive glycinergic inputs, which release both glycine and GABA,
Gao H +5 more
europepmc +2 more sources
Residual Chemical Shift Anisotropies in the Structure Determination of Small Molecules. [PDF]
Magn Reson ChemPlasma neutrophil elastase(ELANE) was markedly elevated in patients with alcohol use disorder, indicating a dysregulated protease‐antiprotease inflammatory balance characterised by decreased SERPINA3. ELANE showed excellent diagnostic specificity(AUC = 0.8683), supporting its potential utility as a neuroinflammatory biomarker for AUD.
Nath N +3 more
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BMC Complementary Medicine and Therapies, 2022 Background Improper use of strychnine can cause death. The aim of this study was to identify and evaluate toxic mechanisms of action associated with active compounds in strychnine using a network toxicology approach, and explore potential pathogenic ...
Jialin Dai +4 more
doaj +1 more source
F1000Research, 2021 Background: Strychnine poisoning is rare but possibly fatal. The most reported sources of strychnine poisoning include rodenticides and adulterated street heroin.
Hok-Fung Tong +3 more
doaj +1 more source
A rare case report of Strychnos nux-vomica poisoning with bradycardia
Journal of Family Medicine and Primary Care, 2017 Strychnine poisoning is a rare method of deliberate self-harm in adults. Poisoning with strychnine leaves is a rare form of strychnine poisoning, as the usual plant parts used are nuts, bark, and seeds.
Lesley Ponraj +3 more
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The functional role of GABA and glycine in monaural and binaural processing in the inferior colliculus of horseshoe bats [PDF]
, 1992 The functional role of GABA and glycine in monaural and binaural signal analysis was studied in single unit recordings from the central nucleus of the inferior colliculus (IC) of horseshoe bats (Rhinolophus rouxi) employing microiontophoresis of the ...
Grothe, Benedikt +3 more
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ON THE DETECTION OF STRYCHNINE. [PDF]
The Lancetn ...
Rodgers, J. E. D., Girdwood, G. Prout
openaire +5 more sources
Interaural time difference processing in the mammalian medial superior olive [PDF]
, 2008 The dominant cue for localization of low-frequency sounds are microsecond differences in the time-of-arrival of sounds at the two ears [interaural time difference (ITD)].
Behrend, Oliver +3 more
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Distinct roles for inhibition in spatial and temporal tuning of local edge detectors in the rabbit retina. [PDF]
, 2014 This paper examines the role of inhibition in generating the receptive-field properties of local edge detector (LED) ganglion cells in the rabbit retina. We confirm that the feed-forward inhibition is largely glycinergic but, contrary to a recent report,
Buldyrev, Ilya +5 more
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Effects of ethylenediamine – a putative GABA-releasing agent – on rat hippocampal slices and neocortical activity in vivo [PDF]
, 2010 The simple diamine diaminoethane (ethylenediamine, EDA) has been shown to activate GABA receptors in the central and peripheral nervous systems, partly by a direct action and partly by releasing endogenous GABA.
Addae, J.I., Lui, C., Stone, T.W.
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