Results 21 to 30 of about 25,312 (210)

Simultaneous HPTLC determination of strychnine and brucine in strychnos nux-vomica seed

open access: yesJournal of Pharmacy and Bioallied Sciences, 2012
Objective: A simple, sensitive, and specific thin layer chromatography (TLC) densitometry method has been developed for the simultaneous quantification of strychnine and brucine in the seeds of Strychnos nux-vomica.
Abid Kamal   +4 more
doaj   +1 more source

The Usefulness of MS3 to Confirm Poisoning on the Example of Dog Poisoning with Strychnine

open access: yesMolecules, 2019
Strychnine is an alkaloid with strong toxic properties. Poisoning results in muscular contractions and death through asphyxiation. Intentional or accidental poisonings with strychnine occur mainly in small animals, especially dogs and occasionally cats ...
Tomasz Śniegocki   +2 more
doaj   +1 more source

Evaluation of antiepileptic activity of the methanol extract of Trachyspermum ammi (L.) [PDF]

open access: yesArchives of Biological Sciences, 2013
This study aims to investigate the effect of a methanol extract of Trachyspermum ammi (L.) as an antiepileptic agent. Tests were conducted with a single- and multiple-dosing schedule of Trachyspermum ammi (L.), using a strychnine-induced seizure model
Rajput Muhammad Ali   +2 more
doaj   +1 more source

The Production and Evaluation of an Electrochemical Sensors for Strychnine and Its Main Metabolite Strychnine N-Oxide for Their Use in Biological Samples

open access: yesMolecules, 2022
Strychnine (STN) and its major metabolite Strychnine N-Oxide (SNO) were examined electrochemically. Both parent compounds and its major metabolite showed electroactivity on glassy carbon electrodes using CV and DPV techniques.
Bakhtiyar Qader   +5 more
doaj   +1 more source

Constitution of Strychnine and the Biogenetic Relationship of Strychnine and Quinine [PDF]

open access: yesNature, 1946
IN 1942 we considered the possibility that strychnine has the constitution shown in (I), but were unable to find satisfactory explanations of all the transformation products on this basis. This difficulty is no longer insuperable, and in the light of new data and a critical review we now believe that the structure interprets the whole behaviour of ...
H T, OPENSHAW, R, ROBINSON
openaire   +2 more sources

Concise Syntheses of bis‐Strychnos Alkaloids (−)‐Sungucine, (−)‐Isosungucine, and (−)‐Strychnogucine B from (−)‐Strychnine [PDF]

open access: yes, 2016
The first chemical syntheses of complex, bis‐Strychnos alkaloids (−)‐sungucine (1), (−)‐isosungucine (2), and (−)‐strychnogucine B (3) from (−)‐strychnine (4) is reported. Key steps included (1) the Polonovski–Potier activation of strychnine N‐oxide; (2) 
Andrade, Rodrigo B.   +11 more
core   +1 more source

Neuroprotection via Strychnine-Sensitive Glycine Receptors During Post-ischemic Recovery of Excitatory Synaptic Transmission in the Hippocampus

open access: yesJournal of Pharmacological Sciences, 2010
Recent evidence indicates that strychnine-sensitive glycine receptors are located in upper brain regions including the hippocampus. Because of excitatory effects of glycine via facilitation of NMDA-receptor function, however, the net effects of increased
Mitsuo Tanabe, Azusa Nitta, Hideki Ono
doaj   +1 more source

ALCOHOLISM AND STRYCHNINE [PDF]

open access: yesThe Journal of Nervous and Mental Disease, 1883
n ...
openaire   +2 more sources

A reverse phased high-pressure liquid chromatographic method for the estimation of a poisonous matter in Strychnos nux-vomica

open access: yesJournal of Advanced Pharmaceutical Technology & Research, 2015
Seeds of Strychnos nux-vomica were subjected to preliminary phytochemical tests and its presence was confirmed by thin layer chromatography (TLC) method. The TLC profile of the methanolic extract of seeds of S.
Achu Hashim   +5 more
doaj   +1 more source

Home - About - Disclaimer - Privacy