Results 31 to 40 of about 41,018 (241)

The full repertoire of Drosophila gustatory receptors for detecting an aversive compound. [PDF]

, 2015
The ability to detect toxic compounds in foods is essential for animal survival. However, the minimal subunit composition of gustatory receptors required for sensing aversive chemicals in Drosophila is unknown.
Jeong, Yong Taek, Kim, Yonjung, Lee, Min Goo, Lee, Youngseok, Montell, Craig, Moon, Seok Jun, Shim, Jaewon   +6 more
core   +2 more sources

Neuroprotection via Strychnine-Sensitive Glycine Receptors During Post-ischemic Recovery of Excitatory Synaptic Transmission in the Hippocampus

Journal of Pharmacological Sciences, 2010
Recent evidence indicates that strychnine-sensitive glycine receptors are located in upper brain regions including the hippocampus. Because of excitatory effects of glycine via facilitation of NMDA-receptor function, however, the net effects of increased
Mitsuo Tanabe, Azusa Nitta, Hideki Ono
doaj   +1 more source

A reverse phased high-pressure liquid chromatographic method for the estimation of a poisonous matter in Strychnos nux-vomica

Journal of Advanced Pharmaceutical Technology & Research, 2015
Seeds of Strychnos nux-vomica were subjected to preliminary phytochemical tests and its presence was confirmed by thin layer chromatography (TLC) method. The TLC profile of the methanolic extract of seeds of S.
Achu Hashim, Rafique Mohammed, Dilshad Umar, Vaswani R Veena, Basheer Bahija, Baroudi Kusai   +5 more
doaj   +1 more source

Nutritional and Physicochemical Characterization of Strychnos madagascariensis Poir (Black Monkey Orange) Seeds as a Potential Food Source

Foods, 2020
Strychnos madagascariensis Poir is an underutilized fruit that is considered a valuable food during droughts and famine. The aim of this research was to characterize the nutritional composition and the flour functional properties, for the use as a ...
Kiana Kirsty van Rayne, Oluwafemi Ayodeji Adebo, Nomali Ziphorah Ngobese   +2 more
doaj   +1 more source

Antiepileptic Effect of Neuroaid^® on Strychnine-Induced Convulsions in Mice

Pharmaceuticals, 2022
NeuroAid II, a folk Chinese Medicine, is currently used in Asia for the treatment of stroke. An experimental study demonstrated that NeuroAid enables neuronal cells to be more resistant to glutamate toxicity. This research was constructed to evaluate the
Ahmed Salim Mahmood, Afaq M. Ammoo, Mayssam Hussein Mohammed Ali, Tiba M. Hameed, Hany A. Al-Hussaniy, Abdulla Amer Abbas Aljumaili, Mohammed Hussein Alaa Al-Fallooji, Ali Hakim Kadhim   +7 more
doaj   +1 more source

Pharmacological Evaluation of Total Alkaloids from Nux Vomica: Effect of Reducing Strychnine Contents

Molecules, 2014
The aim of the study was to investigate the possibility of improving the therapeutic efficacy of the total alkaloid fraction (TAF) extracted from processed nux vomica by reducing the strychnine contents. Most strychnine was removed from TAF to obtain the
Jun Chen, Yange Qu, Dongyue Wang, Pei Peng, Hao Cai, Ying Gao, Zhipeng Chen, Baochang Cai   +7 more
doaj   +1 more source

SALDI Substrate-Based FeNi Magnetic Alloy Nanoparticles for Forensic Analysis of Poisons in Human Serum

Molecules, 2022
In this study, FeNi magnetic alloy nanoparticles (MANPs) were employed for the forensic analysis of four poisons—dimethametryn, napropamide, thiodicarb, and strychnine—using surface-assisted laser desorption/ionization mass spectrometry (SALDI-MS).
Sara A. Al-Sayed, Mohamed O. Amin, Entesar Al-Hetlani   +2 more
doaj   +1 more source

Biosynthesis of strychnine

Nature, 2022
Abstract Strychnine is a natural product that, through isolation, structural elucidation and synthetic efforts, shaped the field of organic chemistry. Currently, strychnine is used as a pesticide to control rodents 1 because of its potent neurotoxicity 2 ...
Benke Hong, Dagny Grzech, Lorenzo Caputi, Prashant Sonawane, Carlos E. Rodríguez López, Mohamed Omar Kamileen, Néstor J. Hernández Lozada, Veit Grabe, Sarah E. O’Connor   +8 more
openaire   +3 more sources

Effect of detoxification (tadbeer) in content of toxic metabolites of Strychnos nux-vomica: A Unani approach for its use in human

Journal of Pharmacy and Bioallied Sciences, 2015
Background: Azaraqi (Strychnos nux-vomica, Loganiaceae) has been the important Unani medicine since long time as a stimulant, anti-inflammatory, and blood purifier. It has been used very frequently by the Unani practitioner.
Noman Anwar, Masood Shah Khan, Hifzul Kabir, Sayeed Ahmad   +3 more
doaj   +1 more source

Pseudopolymorphism in Brucine: Brucine-Water (1/2), The Third Crystal Hydrate of Brucine [PDF]

, 2007
The structure of the third pseudopolymorphic hydrate of brucine, brucine-water (1/2) [systematic name 2,3-dimethoxystrychnidin-10-one-water (1/2)], C23H26N2O4 . 2H2O, has been determined at 130 K.
Smith, Graham, Wermuth, Urs, White, Jonathan   +2 more
core   +2 more sources