Results 91 to 100 of about 666,549 (303)

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Early Grade Retention and Student Success: Evidence From Los Angeles [PDF]

open access: yes, 2011
Analyzes risk factors of retention through third grade in the L.A. Unified School District, including age, gender, race/ethnicity, family income, and English learner status; retention's effectiveness in improving grade-level skills; and educators ...
Jill S. Cannon, Stephen Lipscomb
core  

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Improving models for student retention and graduation using Markov chains. [PDF]

open access: yesPLoS One, 2023
Tedeschi MN   +4 more
europepmc   +1 more source

DIT and Student Retention

open access: yes, 2003
The retention of students and the enhancement of their educational experience must serve as one of the core principles of any institution charged with fulfilling a national and international role in providing full-time and part-time programmes in higher education.
openaire   +4 more sources

Faculty and staff newsletter. [PDF]

open access: yes, 2001
Campus changes -- Housing retention up -- Housing hall director funded -- Humanities Conference Friday and Saturday -- Free speech at the University of Alaska -- Legislators on campus -- Juneau campus -- Sitka campus -- Ketchikan campus -- Students ...

core  

Teacher Knowledge and Classroom Practice: Examining the Connection [PDF]

open access: yes, 2013
This paper extends existing research regarding content knowledge for teaching (CKT) and role it plays in advancing student learning. Two teachers (with high and low measured CKT) are observed on the same day teaching similar content.
Gilbert , Barbara, Gilbert, Michael
core   +2 more sources

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Student Responses to Merit Retention Rules [PDF]

open access: yes
A common justification for HOPE-style merit-aid programs is to promote and reward academic achievement, thereby inducing greater investments in human capital.
Christopher M. Cornwell   +2 more
core  

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