Results 241 to 250 of about 177,707 (371)

Bufalin Inhibits the PI3K/AKT Pathway by Targeting GTF3C4 to Impede Breast Cancer Progression

Advanced Science, EarlyView.
Mechanisms of Bufalin‐Mediated Intervention in Breast Cancer. ABSTRACT Breast cancer incidence is rising globally, presenting challenges such as treatment side effects and drug resistance. Bufalin is a bufadienolides compound with potential anti‐cancer effects. This study shows that bufalin inhibits malignant proliferation of MDA‐MB‐231 and MCF‐7 cells
Siyu Guo, Xiaodong Chen, Haojia Wang, Jiying Zhou, Peiying Lu, Jiangying Liu, Keyan Chai, Jingyuan Zhang, Siyun Yang, Shan Lu, Yifei Gao, Zhengsen Jin, Xiaoyu Tao, Zhongdong Hu, Qinglin Li, Jiarui Wu   +15 more
wiley   +1 more source

Public perception of animal welfare in Iran. [PDF]

Anim Welf
Jalali-Motahari AS, Paterson MBA, Azadian A, Sinclair M.   +3 more
europepmc   +1 more source

Expandable Nanocomposite Shape‐Memory Hemostat for the Treatment of Noncompressible Hemorrhage

Advanced Science, EarlyView.
A nanocomposite‐coated shape memory foam rapidly expands, accelerates clotting, and reduces blood loss in vivo. Its fast volumetric expansion and strong procoagulant activity make it a promising hemostat for treating deep, noncompressible hemorrhage.
Saptarshi Biswas, Sarah E. Miller, Shounak Roy, Jeevika Thazhaiselvam, Samantha Foster, Manivannan Sivaperuman Kalairaj, Sasha M. George, Yava Jones‐Hall, Staci J. Horn, Fred J. Clubb, Taylor H. Ware, Duncan J. Maitland, Akhilesh K. Gaharwar   +12 more
wiley   +1 more source

Single‐Cell RNA Sequencing of Human Lung Tissues Reveals Metallothionein‐Positive T Cells as a Novel Potential Marker of Susceptibility to Chronic Obstructive Pulmonary Disease

Advanced Science, EarlyView.
Using single‐cell RNA sequencing of lung samples and flow cytometry of peripheral blood, we identified a novel T cell subset with high metallothionein (MT) expression. These MT‐high T cells suppress CD8+ T cell cytotoxicity and are progressively depleted from healthy controls to chronic obstructive pulmonary disease (COPD) patients, positioning them as
Zengqing Liu, Xiaoxia Ren, Mi Mu, Huanyu Long, Jialu Lv, Zhihong Feng, Jie Liu, Jiajia Wang, Hui Deng, Fanyu Shi, Muzhi Zhang, Ruoyang Zhang, Yang Liu, Mengyu Xu, Yang Fan, Zengtao Wang, Zhe Lv, Yan Chen, Chris J. Corrigan, Ying Sun, Yahong Chen, Chen Chen, Ye Cui, Wei Wang   +23 more
wiley   +1 more source

Mexiletine prevents transient heart failure in a polymicrogyria child with an ATP1A3 variant: a case report. [PDF]

Eur Heart J Case Rep
Aida M, Ozawa J, Takahashi Y, Miyatake S, Watanabe K.   +4 more
europepmc   +1 more source

Effect of electrical water bath stunning on physical reflexes of broilers: evaluation of stunning efficacy under field conditions

, 2016
Mariagrazia Girasole, Raffaele Marrone, Aniello Anastasio, Antonio Chianese, Raffaelina Mercogliano, Maria Luisa Cortesi   +5 more
openalex   +1 more source

High frequency pre-slaughter electrical stunning in ruminants and poultry for halal meat production: A review

, 2017
A. Sabow, K. Nakyinsige, K. Adeyemi, A. Sazili, C. Johnson, J. Webster, M. Farouk   +6 more
semanticscholar   +1 more source

Stochastic Nanoscale Biophysical Cues as a Basis for the Induction of Glioblastoma‐Like Transcriptional Programs in Astrocytes

Advanced Science, EarlyView.
Stochastic nanoscale physical cues induce glioblastoma (GBM)‐associated transcriptional traits in naïve astrocytes leading to spontaneous formation of spheroids. Cells within spheroids express activated‐MMP2 and a differential gene expression pattern involving P53 and NOTCH3, providing evidence for a role for changes in brain topography, as observed in
Laurent Starck, Tobias Butelmann, Sabrina Hogan, Melika Sarem, Bernd Heimrich, Ritwick Sawarkar, Marie‐Françoise Ritz, Gregor Hutter, V. Prasad Shastri   +8 more
wiley   +1 more source

Effectiveness of electrical stunning and bleeding in finishing pigs: a case study from procedures to practice at two modern Colombian abattoirs. [PDF]

Trop Anim Health Prod
Pastrana-Camacho AP, Estévez-Moreno LX, Huanca-Marca NF, la Lama GCM.   +3 more
europepmc   +1 more source

Glucagon-Like Peptide-1–Mediated Cardioprotection Does Not Reduce Right Ventricular Stunning and Cumulative Ischemic Dysfunction After Coronary Balloon Occlusion

, 2019
Joel P. Giblett, Richard G. Axell, Paul A. White, Muhammad Aetesam‐ur‐Rahman, Sophie Clarke, Nicola Figg, Martin R. Bennett, Nick E.J. West, Stephen P. Hoole   +8 more
openalex   +2 more sources