Results 241 to 250 of about 147,460 (329)

Induction of pro-apoptotic Bcl-Xs protein expression during myocardial infarction but not after stunning Bysani Chandrasekar, Gregory L. Freeman. University of Texas Health Science Center, San Antonio, TX

, 2001

openalex   +1 more source

Responsive ROS‐Augmented Prodrug Hybridization Nanoassemblies for Multidimensionally Synergitic Treatment of Hepatocellular Carcinoma in Cascade Assaults

Advanced Science, EarlyView.
This study proposes a novel HCC therapy using CA‐4S2@ES‐Cu nanomedicines to amplify cuproptosis, enhancing chemotherapy and immunotherapy. CA‐4 and ES‐Cu synergistically inhibit tumor growth, induce immune responses, and reverse the immunosuppressive microenvironment, offering an effective multidimensional therapeutic strategy for HCC treatment ...
Yingjie Zeng, Yuening Cao, Senmiao Ren, Chaozheng Zhang, Jianan Liu, Ke Liu, Yan Wang, Hongyu Chen, Fengjiao Zhou, Xiuli Yang, Xian Ge, Tingting Zhang, Tianbao Wang, Yao He, Defang Li, Chuantao Zhang, Jun Lu   +16 more
wiley   +1 more source

Pathophysiology of Penetrating Captive Bolt Stunning in Horned and Polled Sheep and Factors Determining Incomplete Concussion. [PDF]

Vet Sci
Gibson TJ, Ridler AL, Limon G, Lamb C, Williams A, Gregory NG.   +5 more
europepmc   +1 more source

Repetitive myocardial ischaemia at intervals associated with stunning can be detected by diastolic but not systolic parameters measured by tissue doppler R. Ian Williams, Navroz D. Masani, Alan G. Fraser. Wales Heart Research Institute, University Hospital of Wales, Heath Park, Cardiff, United Kingdom

, 2001

openalex   +1 more source

A MXene‐Based Nanothermal Knife Inhibits Aggresome‐Mediated Persister Formation for Preventing Dental Caries

Advanced Science, EarlyView.
Early childhood caries (ECC) involves cariogenic persisters that evade antimicrobial treatment. Persisters achieve this by downregulating heat shock proteins (HSPs) and formation of protein aggregates. Ti3C2 MXene‐based photothermal therapy (PTT) acts as a “nanothermal knife,” disrupting membranes, upregulating HSPs, inhibits aggregates, prevents ...
Yinyin Zhang, Leilei Yang, Jing jiao, Wenshuai Li, Sen Lin, Xianlong Zong, Haoyang Qin, Danfeng Liu, Rui Li   +8 more
wiley   +1 more source

The use of sacubitril/valsartan in different forms of heart failure. [PDF]

Int J Cardiol Heart Vasc
Abumayyaleh M, Hamdani N, El-Battrawy I, Akin I.   +3 more
europepmc   +1 more source

Repeated episodes of myocardial stunning are cumulative in man Edward Barnes, David P. Dutka, Masood Khan, Roger J. C. Hall, Paolo G. Camici. MRC Clinical Sciences Centre, NHLI at Hammersmith Hospital, London, United Kingdom, Division of Cardiology, NHLI at Hammersmith Hospital, London, United Kingdom

, 2001

openalex   +1 more source

Inhibition and Rescue of Hyperglycemia‐Induced Cellular Senescence by Mitochondrial Transfer from Enucleated Mesenchymal Stem Cell‐Derived Microvesicles for Chronic Wound Healing

Advanced Science, EarlyView.
This study develops enucleated MSC‐derived microvesicles (Mito@euMVs) to deliver functional mitochondria for optimizing wound repair. By efficiently encapsulating mitochondria, Mito@euMVs rejuvenate hyperglycemia‐induced senescent fibroblasts and HUVECs. Using PVA microneedle patches, the therapeutic efficacy of Mito@euMVs is validated in diabetic rats
Zixuan Dong, Xiaobing Liu, Shichun Li, Xiaoling Fu   +3 more
wiley   +1 more source

Beat-to-beat alternans. [PDF]

Korean J Intern Med
Lee CH, Scheinman MM.
europepmc   +1 more source

STAT6 Activation Exacerbates Ferroptosis in Airway Epithelium by Inhibiting PRKN‐Mediated Mitophagy in Pulmonary Fibrosis

Advanced Science, EarlyView.
This study uncovers STAT6‐driven pulmonary fibrosis (PF) via suppression of PRKN‐mediated airway epithelial mitophagy, triggering mitochondrial dysfunction and ferroptosis. Rifabutin is identified as a potent STAT6 inhibitor that effectively reverses fibrotic progression. These findings reveal the STAT6‐PRKN axis as a pathogenic regulator and provide a
Youjing Yang, Guangbin Huang, Tao Zhang, Yi Ling, Junyu Jiang, Dingyuan Du, Yu Ma, Shasha Tao   +7 more
wiley   +1 more source