Results 181 to 190 of about 10,616 (208)

TP53 Loss Elevates NF‐κB‐IFN‐β‐MHC‐Ia Signaling to Promote NK Cell Resistance in Osteosarcoma

Advanced Science, EarlyView.
TP53 loss in a transforming or osteosarcoma cell promotes cytosolic DNA accumulation, activating NF‐κB‐dependent IFN‐β production. Autocrine IFN‐β signaling increases cell‐surface HLA‐Ia expression, strengthens inhibitory KIR signaling in natural killer cells, and thereby enables the affected cell to evade NK cell‐mediated cytotoxicity.
Guihui Qin, Cheung Kwan Yeung, Ye Yi, Dejin Zheng, Miaoman Ye, Chi‐Chong Chio, Jinjie Wu, Siyi Fu, Chu‐Xia Deng, Ren‐He Xu   +9 more
wiley   +1 more source

A 3D‐Printed SFE‐Graded Alloy Mitigates Cryogenic Discontinuous Plastic Flow and Hydrogen Embrittlement

Advanced Science, EarlyView.
A novel strategy features gradient composition and stacking fault energy‐tuned (CoCrMn)100‐2xFexNix fabricated via in situ alloying additive manufacturing. This design circumvents cryogenic discontinuous plastic flow and hydrogen embrittlement of metallic materials under quasi‐static loading and hydrogen‐rich environment relevant to lunar polar ...
Renhao Wu, Ao Geng, Peihao Geng, Hyojin Park, Eun Seong Kim, Sang‐Ho Oh, Stephan Schönecker, Xiaoqing Li, Tianlong Zhang, Shuhui Li, Byeong‐Joo Lee, Hyoung Seop Kim   +11 more
wiley   +1 more source

Rainbow trout welfare: comparing stunning methods in winter and summer. [PDF]

Fish Physiol Biochem
González-Garoz R, Cabezas A, Fernández-Muela M, Martínez Villalba A, González de Chávarri E, Villarroel M, De la Llave-Propín Á, De la Fuente J, Bermejo-Poza R, Díaz MT.   +9 more
europepmc   +1 more source

Adhesion‐Enhanced Engineered Probiotic for Prolonged Intestinal Retention and Calprotectin‐Responsive IBD Therapy

Advanced Science, EarlyView.
An intelligent engineered probiotic platform is developed for the precision management of inflammatory bowel disease. By integrating surface‐displayed adhesins with an inflammation‐responsive CAT‐SOD‐GPx tripartite fusion system and mucosal repair factors, this programmable system achieves prolonged intestinal retention and multi‐pronged therapy.
Yuxi Wang, Peichao Zhang, Simin Gu, Hongyun Lu, Ningning Jiang, Jiarun Zhao, Enbo Xu, Xiayu Liu, Ying Shi, Qihe Chen   +9 more
wiley   +1 more source

Isolated Right Ventricular Takotsubo Cardiomyopathy: Beyond the Left Ventricle. [PDF]

JACC Case Rep
Takagi MA, Xu J, Diaz AP, Vicks W, Pham T, Takeda P, Low R.   +6 more
europepmc   +1 more source

Effects of Pulmonary Vein Isolation on Left Atrial Hemodynamic and Mechanical Function: Insights from Advanced and Emerging Echocardiographic Parameters in Responders and Non-Responders. [PDF]

J Cardiovasc Dev Dis
Kozielski J, Olczyk M, Szołkiewicz M.
europepmc   +1 more source

Severe Biventricular Takotsubo Syndrome Triggered by Status Epilepticus With Pulmonary Embolism and Critical Illness Myopathy. [PDF]

JACC Case Rep
Dontamsetty A, Itoo UB, Kour R, Alexander Santhi JL, Khan M.   +4 more
europepmc   +1 more source

Vertebral artery contribution to cerebral cortex perfusion in cattle after slaughter by ventral neck incision: a systematic review. [PDF]

Front Vet Sci
Hascalovici JR, Pozzi P, Yvorchuk K, St-Jean G, Rosen SD.   +4 more
europepmc   +1 more source

Can Resting Segmental Strain Identify Obstructive Coronary Artery Disease in Chronic Coronary Syndrome Patients Referred to Coronary Artery Bypass Grafting?

Cardiology
Rösner A, Kjønås D, Sandberg ML, Dalen H, Schirmer H.   +4 more
europepmc   +1 more source