Acute and sub-chronic toxicity study of recombinant bovine interferon alpha in rodents [PDF]
Journal of Veterinary Research, 2021 Abstract Introduction Recombinant bovine interferon alpha (rBoIFN-α) has been demonstrated to have antiviral activity. However, no conduct of acute or chronic toxicity tests has been reported. Material and Methods Specific pathogen ...
Yu Hai-Yang +8 more
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Evaluation of Acute and Sub-Chronic Toxicity of Lactobacillus rhamnosus GG in Sprague-Dawley Rats [PDF]
Advanced Biomedical ResearchBackground: Probiotic-based bacteriotherapy has emerged as a potentially effective strategy for preventing infectious diseases. Lactobacillus strains consumed as probiotics and the safety of these spp.
Vedam Venkata Kanthi Vaishnavi +4 more
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A botanical from the antiproliferative Cameroonian spice, Imperata cylindrica is safe at lower doses, as demonstrated by oral acute and sub-chronic toxicity screenings [PDF]
BMC Complementary Medicine and Therapies, 2020 Background The cytotoxicity of the root’s methanol extract of Imperata cylindrica (ICR). was previously reported in a panel of human cancer cell lines, including multi-drug resistant phenotypes.
Paul Nayim +3 more
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Nanobubble Ozone Stored in Hyaluronic Acid-Decorated Liposome Solutions: Inactivating Antibiotic-Resistant Bacteria and Genotoxicity, Sub-Acute and Sub-Chronic Toxicity Tests [PDF]
Infection and Drug ResistancePerihan Erkan Alkan,1 Talha Karabiyik2 1Department of Medical Microbiology, Faculty of Medicine, Bandırma Onyedi Eylül University, Bandırma,/Balıkesir, Turkey; 2Department of Medical Biochemistry, Faculty of Medicine, Bandırma
Erkan Alkan P, Karabiyik T
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Sub-chronic Toxicity Study of Heracleumlasiopetalum Extract Towards Healthy Sprague Dawley Rats [PDF]
Iranian Journal of Pharmaceutical ResearchBackground: Heracleum species are commonly used as spices, flavorings, and food additives. Members of the genus Heracleum offer many medicinal benefits but may also pose adverse effects on human health. Objectives: To prepare a crude leaf extract of Heracleumlasiopetalum and assess its toxicity profile towards healthy rats. Methods: The H. lasiopetalum
Enas Sabah Hassan +2 more
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Acute and sub-chronic oral toxicity study of purple sweet potato (Ipomoea batatas [L.] Lam) yogurt in mice (Mus musculus) [PDF]
Veterinary World, 2022 Background and Aim: Food safety is an important aspect to be evaluated in preventing any potentially harmful side effects of food product such as yogurt. The purple sweet potato yogurt product was developed to combine the benefits of probiotic activities
Astrid Feinisa Khairani +7 more
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Indonesian Journal of Pharmacy, 2021 This research aimed to evaluate the toxicity of 1-(2, 5-dihidroxyphenil)-3-pyridine-2-il-propenone (DPP) after 24 hours and 90-day administration in female mice. Acute toxicity test was performed using the OECD 423 method, and DPP was administered once a
Ika Puspitasari +6 more
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Acute and subchronic oral toxicity assessments of Combretum micranthum (Combretaceae) in Wistar rats
Toxicology Reports, 2020 Background: Combretum micranthum (CM) (Combretaceae) is widely used in traditional medicine throughout West Africa for the treatment of diabetes, hypertension, inflammation, malaria and liver ailments.
Mabozou Kpemissi +11 more
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Monte Carlo Models for Sub-Chronic Repeated-Dose Toxicity: Systemic and Organ-Specific Toxicity
International Journal of Molecular Sciences, 2022 The risk-characterization of chemicals requires the determination of repeated-dose toxicity (RDT). This depends on two main outcomes: the no-observed-adverse-effect level (NOAEL) and the lowest-observed-adverse-effect level (LOAEL). These endpoints are fundamental requirements in several regulatory frameworks, such as the Registration, Evaluation ...
Gianluca Selvestrel +7 more
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Thallium Induced Sub-chronic Toxicity Profile in Wistar Rats
Indian Journal of Veterinary Sciences & Biotechnology, 2022 Thallium (Tl) is one of the most toxic heavy metals affecting both humans and animals, yet is one of the least studied for its toxicological effects. A total of 40 male Wistar rats were randomly divided into four Groups with 10 rats in each Group. Group I received distilled water only and served as a control.
Parvez I. Sindhi +6 more
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