Results 71 to 80 of about 780 (181)
Fenugreek seeds, a hepatoprotector forage crop against chronic AlCl3 toxicity
BMC Veterinary Research, 2013 Background Having considered how bioavailable aluminium (Al) may affect ecological systems and animals living there, especially cattle, and in search for a preventive dietary treatment against Al toxicity, we aimed to test the protective role of ...
Belaïd-Nouira Yosra +6 more
doaj +1 more source
Bio‐Inspired Synthesis of Macroporous Single Crystal Particles as Scattering Agents
Advanced Functional Materials, EarlyView.A general strategy is presented that delivers unique, single‐crystal microparticles that combine submicron macroporosity and uniform particle shapes. A bioinspired approach is used to occlude three distinct types of additives – polystyrene microspheres, polymer vesicles and amino acids – within calcite single crystals, and subsequent thermal annealing ...
Stephanie E. Foster +11 more
wiley +1 more source
Advanced Functional Materials, EarlyView.A bio‐inspired biopolymeric implantable drug delivery platform enables localized and sustained release of 7‐ethyl‐10‐hydroxycamptothecin (SN‐38) in solid tumor treatment. The three‐dimensional (3D) structured crosslinked‐chitosan implants are fabricated via 3D‐printed molds and provide drug release over 3 months, significantly inhibiting tumor growth ...
Mercedes Lozano‐Garcia +12 more
wiley +1 more source
A k-NN algorithm for predicting oral sub-chronic toxicity in the rat
ALTEX, 2014 Repeated dose toxicity is of the utmost importance to characterize the toxicological profile of a chemical after repeated administration. Its evaluation refers to the Lowest-Observed-(Adverse)-Effect-Level (LO(A)EL) explicitly requested in several regulatory contexts, such as REACH and EC Regulation 1223/2009 on cosmetic products.
GADALETA, DOMENICO +6 more
openaire +4 more sources
Advanced Functional Materials, EarlyView.Oligomerizing Pluronic triblock copolymers provides a processing strategy for tuning the mechanical properties and stimuli‐responsive behaviors of micellar hydrogels. Varying oligomer fraction produces hydrogels spanning brittle to highly extensible responses; maintaining micellar architectures enables cooling‐induced reverse thermal shape memory and ...
Gourav Kumbhojkar +8 more
wiley +1 more source
Evaluation of sub-chronic oral toxicity of Joloo: A traditional medicinal decoction
Pharmaceutical Biology, 2011 Joloo is a Nigerian herbal decoction used for managing breast tumor, ulcer, pain, fever and general malaise in southwestern Nigeria.The evaluation of the sub-chronic toxicity of Joloo, a Nigerian herbal decoction, is done by investigating its effects on biochemical, antioxidant, histopathologic and hematologic indices in normal albino rats.Albino rats ...
Adeola, Oloyede +3 more
openaire +2 more sources
Thermoresponsive Soft and Self‐Anchoring Cuff Electrode for Chronic Peripheral Interfaces
Advanced Functional Materials, EarlyView.A novel thermoresponsive, soft and self‐anchoring (TSSA) cuff electrode utilizing shape memory polymers achieves autonomous, sutureless peripheral nerve fixation. Driven by thermally induced pre‐strain and tissue adhesion, the device self‐closes and softens at body temperature, successfully minimizing mechanical mismatch. This adaptive platform ensures
Seungjun Lee +4 more
wiley +1 more source
Sub–chronic toxicity and heavy metal toxicity study on Kappaphycus alvarezii in albino rats
Asian Pacific Journal of Tropical Biomedicine, 2012 Abstract Objective This study aimed to evaluate the toxicity of Kappaphycus alvarezii methanolic extracts in albino rats. Methods Sub–chronic toxicity was tested with a single dose of intraperitonal administration of the extract as per the OECD guidelines in the experimental group rats and the control group rats was fed with standard diet and ...
R.G. Abirami, S. Kowsalya
openaire +1 more source
Advanced Healthcare Materials, EarlyView.This study explores how the brain responds to implants of different properties. Hydrogels with various mechanical properties and pore sizes were implanted in adult rat brains. It is observed that hydrogels with mechanical property closely matched to the brain and 40 µm pore size elicit a pro‐healing response from the brain by modulating the immune ...
Ian Dryg +8 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.Mitochondria‐targeted nanotherapies emerge as a promising strategy for combating aging‐associated neurodegenerative disorders (NDs) by restoring mitochondrial function, reducing oxidative stress, and improving neuronal survival. Recent advances in nanotechnology, therapeutic delivery, and translational research are highlighted, providing insights into ...
Dnyandev G. Gadhave +8 more
wiley +1 more source