Results 41 to 50 of about 3,948 (161)
Background: Subacute cutaneous lupus erythematosus (SCLE) manifests with erythematous, nonscarring, annular, or papulosquamous plaques. Proton pump inhibitors (PPIs) are increasingly being incriminated in its causation, but reports of similar nature from
Sukhjot Kaur +5 more
doaj +1 more source
Plasma Cell Mucositis: A 20‐Year Retrospective Review at a Tertiary Center
ABSTRACT Background Plasma cell mucositis (PCM) is a rare, chronic inflammatory condition of mucosal surfaces that is likely underdiagnosed and underreported, with limited data on its clinical characteristics, extracavitary involvement, and treatment outcomes.
Miguel A. Aristizabal‐Torres +4 more
wiley +1 more source
ABSTRACT Dermatitis herpetiformis (DH) is a rare, intensely pruritic cutaneous manifestation of celiac disease (CD), typically presenting with excoriated papulovesicular lesions on extensor surfaces. DH is associated with IgA autoantibodies against epidermal transglutaminase (eTG), which form granular immune deposits in the papillary dermis and induce ...
Jeffrey Damman +5 more
wiley +1 more source
Inborn errors of immunity in children with neuroinflammation
Abstract Inborn errors of immunity (IEIs), an expanding group of monogenic disorders with diverse clinical manifestations, are increasingly recognized to include neuroinflammatory disease. Examples of diseases included under this umbrella are Aicardi–Goutières syndrome, deficiency of adenosine deaminase 2, familial haemophagocytic lymphohistiocytosis ...
Eppie M Yiu +5 more
wiley +1 more source
This bicentric study of 95 CCLE patients shows SLE prevalence (21.1%–31.6%) varies significantly by classification criteria. Arthralgia was a consistent independent risk factor across all systems. Our findings support the implementation of systematic risk‐stratified screening protocols for CCLE patients, with particular attention to joint symptoms and ...
Noureddine Litaiem +4 more
wiley +1 more source
Litifilimab efficacy on skin outcomes in cutaneous lupus erythematosus in the Phase 2 LILAC study
Our findings show that greater proportions of litifilimab‐treated participants than placebo experienced 20%, 50%, 70% or 90% improvements in CLASI‐A score from baseline and CLASI‐A scores of 0–1 or 0–3. Similar results were observed using physician global assessments, supporting the Phase 2 LILAC study primary analysis in CLE.
Victoria P. Werth +8 more
wiley +1 more source
Cutaneous lupus erythematosus: An update
Lupus erythematosus (LE) is a chronic, autoimmune, multisystem disease that displays many diverse symptoms in which localized cutaneous LE (CLE) is on one end of the spectrum and severe systemic LE (SLE) on the other end.
Carina M Grönhagen, Filippa Nyberg
doaj +1 more source
Pregnancy and lactation during anifrolumab treatment in systemic lupus erythematosus
Dear Editor, Systemic lupus erythematosus (SLE) is a chronic multisystem autoimmune disease that predominantly affects women of childbearing age. Cutaneous involvement represents one of the most common clinical manifestations of SLE and may occur in ...
Maria Bernardette Cilona +9 more
doaj +1 more source
Blaschko lines are manifestations of cutaneous mosaicism, with apparent contrast between normal cells and abnormal cells, which carry postzygotic mutations.
Sebastian Yu, Hsin-Su Yu
doaj +1 more source
Incidence of cutaneous lupus erythematosus and systemic progression: A Nationwide study in Korea
This nationwide study reports a cutaneous lupus erythematosus (CLE) incidence of 3.98/100,000 person‐years. CLE was associated with an increased risk of actinic keratosis and skin cancer. Progression to SLE clustered within 5 years after CLE diagnosis, with a 5‐year cumulative incidence of 11.4%, supporting a risk‐stratified follow‐up approach during ...
Seon Young Song +3 more
wiley +1 more source

