Results 61 to 70 of about 3,948 (161)

A Novel Use of Anifrolumab for a Novel Disease

ACR Open Rheumatology, Volume 8, Issue 5, May 2026.
Objective To explore the potential role of type‐I interferon (IFN‐I) signaling in autoimmune cytopenias outside the context of systemic lupus erythematosus (SLE), and to evaluate the clinical response to off‐label anifrolumab in two patients with fatigue and immune‐mediated cytopenias who did not meet established criteria for SLE.
Zachary Holtz, Adam Schulz, Alexa Meara
wiley   +1 more source

The First Case of Linear Cutaneous Lupus Erythematosus Following Covid‐19 Vaccination: A Case Report

Clinical Case Reports, Volume 14, Issue 5, May 2026.
Clinical manifestation of LCDLE characterized by lesions following a progressive distal pattern along the lateral arm, forearm, and dorsal hand. ABSTRACT Linear cutaneous discoid lupus erythematosus (LCDLE) is a rare presentation of lupus erythematosus, more frequently observed in children and young adults.
Fatemeh Saberi, Alireza Ghanadan, Zahra Razavi, Vahideh Sadat Azhari, Marwa Akhdar, Saman Al‐Zahawi   +5 more
wiley   +1 more source

“Reactions in Leprosy: Updated Insights Into Pathophysiology, Clinical Spectrum, and Therapeutic Approaches—A Narrative Review”

Health Science Reports, Volume 9, Issue 5, May 2026.
ABSTRACT Background and Aims Reaction in leprosy is an immune‐mediated acute inflammatory episodes that occur in the natural course of Hansen's disease. Reaction can occur before, during, or after starting multidrug therapy and is a major cause of nerve damage, morbidity, and disability in affected individuals.
Bhaskar Gupta, Manesha Singh, Mohamad Goldust, Kinnor Das, Surajit Gorai, Prajwal Pudasaini, Seema Sitaula, Achyut Pokhrel, Esna Thapa, Sunil Jaiswal   +9 more
wiley   +1 more source

Topical calcineurin inhibitors in systemic lupus erythematosus

Therapeutics and Clinical Risk Management, 2010
Christos E Lampropoulos, David P D’CruzLupus Research Unit, Rayne Institute, St. Thomas’ Hospital, London, UKAbstract: Cutaneous lupus erythematosus (CLE) encompasses a variety of lesions that may be refractory to systemic or topical ...
Christos E Lampropoulos, David P D’Cruz   +1 more
doaj  

Subacute cutaneous lupus erythematosus onset preceded by Kikuchi-Fujimoto disease

Dermatology Practical & Conceptual, 2014
Kikuchi-Fujimoto disease (KFD) is an uncommon clinicopathological entity characterized by fever and lymphadenopathy, predominantly involving cervical lymph nodes, accompanied by chills and leukopenia.
Vito Di Lernia, Gianluigi Bajocchi, Simonetta Piana   +2 more
doaj   +1 more source

Severely crusted cheilitis as an initial presentation of systemic lupus erythematosus

Indian Journal of Dermatology, 2017
Lupus erythematosus (LE) is an autoimmune disease which may initially present solely with lip lesions. Due to a wide spectrum of presentation, these features may initially be misdiagnosed as other oral diseases such as lichen planus, erythema multiforme (
Wai Man Mandy Chan, Shiu Ming Pang, See Ket Ng   +2 more
doaj   +1 more source

Significant improvement of refractory cutaneous lesions of lupus erythematosus with the use of anifrolumab: a report of two cases

Revista da Sociedade Portuguesa de Dermatologia e Venereologia
Anifrolumab, a monoclonal antibody targeting the interferon-1 receptor, is currently approved for the treatment of moderate- to-severe systemic lupus erythematosus, but emerging evidence highlights its potential efficacy in cases with predominant ...
Gilberto P. da Rosa, Isabel Antunes, Bárbara V. Granja, Patrícia Gomes, Rúben Costa, Filomena Azevedo, Alberto Mota   +6 more
doaj  

Lansoprazole-Induced Subacute Cutaneous Lupus Erythematosus

The Turkish Journal of Gastroenterology, 2017
A 23-year-old female patient presented with a one-week history of itchy skin lesions distributed on the upper chest, extensor sides of the arms, and the trunk. Two weeks earlier, the patient had been prescribed lansoprazole 40 mg/day due to the symptoms
İsa AN, Vasfiye DEMİR, İbrahim İBİLOĞLU, Sedat AKDENİZ, Derya UÇMAK   +4 more
doaj  

Cytokines and Effector/Regulatory Cells Characterization in the Physiopathology of Cutaneous Lupus Erythematous: A Cross-Sectional Study

Mediators of Inflammation, 2016
We compared the presence of diverse cytokines and regulatory T and B cells in skin biopsies of discoid lupus erythematosus (DLE) and subacute cutaneous lupus erythematosus (SCLE).
Silvia Méndez-Flores, Gabriela Hernández-Molina, Ana Bety Enríquez, David Faz-Muñoz, Yeraldin Esquivel, Carlos Pacheco-Molina, Janette Furuzawa-Carballeda   +6 more
doaj   +1 more source

Drug-induced lupus erythematosus

Revista da Sociedade Portuguesa de Dermatologia e Venereologia, 2023
Drug-induced lupus erythematosus is an autoimmune disease with unexpected onset after treatment with certain drugs. Clinically, this disease is very similar to idiopathic lupus erythematosus, although its manifestations are typically milder. In addition,
Ana L. Gouveia, Margarida Gonçalo
doaj