Results 51 to 60 of about 3,948 (161)
In this cross‐sectional study of 45 patients, including 30 with cutaneous lupus erythematosus and 15 with rosacea, line‐field confocal optical coherence tomography (LC‐OCT) identified in vivo microarchitectural patterns. Acute and subacute cutaneous lupus were characterized predominantly by interface dermatitis, including dermoepidermal junction ...
Daniele Omar Traini +17 more
wiley +1 more source
ABSTRACT Primary Sjögren's syndrome (pSS) is a chronic autoimmune disorder. Dysregulated interferon‐gamma (IFN‐γ) signalling is implicated in pSS pathogenesis, yet the underlying mechanisms remain elusive. This study aimed to identify key IFN‐γ‐associated diagnostic genes and delineate their roles in immune dysregulation using peripheral blood ...
Lei Shi, Tian‐chi Wei, Jing Zhang
wiley +1 more source
Ro60 and La ribonucleoproteins become self-aggregated by cell stress
Ro is a cellular particle composed by three ribonucleoproteins of 60, 54 and 52 kDa (1-3). Ro60 forms a complex with one of the 1-5 hYRNAs (4). Antigenic properties of Ro were described by Clark in 1969 using autoimmune sera (5), and it is broadly ...
E. Avalos-Díaz +3 more
doaj +1 more source
Background: Vesicular cutaneous lupus erythematosus (VCLE) is a rare autoimmune disease in dogs and is considered the canine counterpart of human subacute cutaneous lupus erythematosus (SCLE). However, the molecular mechanisms underlying VCLE remain incompletely defined.
Treasa Clifford +5 more
wiley +1 more source
Evolving treatments for Sjögren disease: current approaches and emerging targets
Abstract Sjögren disease (SjD) is a prevalent systemic autoimmune condition characterised by exocrine gland dysfunction, systemic inflammation and heterogeneous organ involvement. Current management remains largely symptomatic, with no approved disease‐modifying therapies available and substantial unmet clinical need. However, advances in understanding
Mansi Bhurani +3 more
wiley +1 more source
Rituximab, a chimeric anti-CD20 monoclonal antibody, is widely used to treat autoimmune diseases and hematologic malignancies through B-cell depletion, yet paradoxical autoimmune phenomena, including drug-induced lupus erythematosus, have been ...
I. Magi +9 more
doaj +1 more source
A 35-year-old female presented with scaly annular and pigmented lesions all over the body of 2 years duration. Her clinical features, histopathology, immunofluorescence findings and positive ANA and anti-Ro antibodies were suggestive of subacute ...
C Shanmuga Sekar +3 more
doaj +1 more source
Immunotherapy‐Related Cutaneous Toxicities in Melanoma: A Dermoscopic Perspective
Dermoscopy serves as a valuable tool in the everyday dermatological and oncological practice for melanoma patients, allowing for the prompt identification of immune‐related cutaneous toxicities and guiding clinicians toward appropriate therapeutic decisions.
Grażyna Kamińska‐Winciorek +3 more
wiley +1 more source
Associação entre lúpus eritematoso e tabagismo Association between lupus erythematosus and smoking
FUNDAMENTOS: O lúpus eritematoso é doença crônica, auto-imune, que reúne manifestações exclusivamente cutâneas ou multissistêmicas, caracterizada pela produção de auto-anticorpos contra vários constituintes celulares.
Júnia Maria Fernandes Araújo +4 more
doaj +1 more source
Journal of the European Academy of Dermatology and Venereology, EarlyView.
Joseph F. Merola +6 more
wiley +1 more source

