Results 101 to 110 of about 820,988 (298)
FEBS Open Bio, EarlyView.Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas +6 more
wiley +1 more source
Molecular Plant-Microbe Interactions, 2006 Previously, we identified a correlation between the interaction of the Tobacco mosaic virus (TMV) 126/183-kDa replicase with the auxin response regulator indole acetic acid (IAA)26/PAP1 and the development of disease symptoms.
Meenu S. Padmanabhan +2 more
doaj +1 more source
Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy
FEBS Open Bio, EarlyView.This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan +11 more
wiley +1 more source
Advancing mRNA subcellular localization prediction with graph neural network and RNA structure
Motivation The asymmetrical distribution of expressed mRNAs tightly controls the precise synthesis of proteins within human cells. This non-uniform distribution, a cornerstone of developmental biology, plays a pivotal role in numerous cellular processes.
Tan, Xiaolan +5 more
core +1 more source
Prediction of Protein Subcellular Localization: A Machine Learning Approach [PDF]
, 2010 Subcellular localization is a key functional characteristic of proteins. Optimally combining available information is one of the key challenges in today's knowledge-based subcellular localization prediction approaches.
SHIM, Kyong Jin
core
Subcellular localization of OsNRAMP3 protein.
, 2013 Subcellular localization of OsNRAMP3 protein was determined in Arabidopsis protoplasts. The confocal images were acquired using a confocal laser scanning microscope (TCS SP2; Leica).
Wan Zhang (477556) +6 more
core +1 more source
Evolution‐guided yeast complementation reveals functional differences in human PSPH variants
FEBS Open Bio, EarlyView.Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez +6 more
wiley +1 more source
Nano Convergence, 2018 In this article, we elaborate the application of thermal decomposition based synthesis of Fe3O4 superparamagnetic nanoparticle (SPMNP) in subcellular fractionation context.
Deepak B. Thimiri Govinda Raj +1 more
doaj +1 more source
Quantitative BiologyLong noncoding RNAs (lncRNAs) are crucial in gene regulation, chromatin architecture, and cellular differentiation, playing significant roles in various diseases and serving as potential biomarkers and therapeutic targets.
Yujia Cheng, Xiaoyong Pan, Yang Yang
doaj +1 more source
Single-cell Protein Localization Method Based on Class Perception Graph Convolutional Network
Shengwu huaxue yu shengwu wuli jinzhanObjectiveThis study proposes a novel single-cell protein localization method based on a class perception graph convolutional network (CP-GCN) to overcome several critical challenges in protein microscopic image analysis, including the scarcity of cell ...
TANG Hao-Yang +3 more
doaj +1 more source