Results 71 to 80 of about 820,988 (298)

Subcellular localization of LIP5.

, 2014
(A) Effect of pathogen infection on LIP5 subcellular localization. Transgenic Arabidopsis plants expressing LIP5-GFP was infiltrated with PstDC3000 (OD600 = 0.0002 in 10 mM MgCl2).
Jing-Quan Yu (102564), Zhixiang Chen (23839), Baofang Fan (23837), Fei Wang (19534), Yifen Shang (596136)   +4 more
core   +1 more source

Attentional BiLSTM and Prototype Networks for lncRNA Subcellular Localization Prediction [PDF]

Jisuanji gongcheng
Long non-coding RNA (lncRNA) are crucial in many cellular life processes, and their subcellular localization can provide key information for their functional identification.
SUN Rongneng, LIU Lin, KANG Yuanzhao
doaj   +1 more source

Characterizing functional domains of the RNA helicase RHAU involved in subcellular localization and RNA interaction [PDF]

, 2008
Posttranscriptional regulation of gene expression is an important and highly regulated process in response to developmental, environmental and metabolic signals.
Chalupníková, Katerina
core   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

ELLA: modeling subcellular spatial variation of gene expression within cells in high-resolution spatial transcriptomics

Nature Communications
Spatial transcriptomics technologies are becoming increasingly high-resolution, enabling gene expression measurement at the subcellular level. Here, we present subcellular expression localization analysis (ELLA), a statistical framework for modeling ...
Jade Xiaoqing Wang, Xiang Zhou
doaj   +1 more source

An incremental approach to automated protein localisation [PDF]

, 2008
Tscherepanow M, Jensen N, Kummert F. An incremental approach to automated protein localisation. BMC Bioinformatics. 2008;9(1): 445.Background: The subcellular localisation of proteins in intact living cells is an important means for gaining information ...
Kummert Franz, Tscherepanow Marko, Tscherepanow, Marko, Kummert, Franz, Jensen Nickels, Jensen, Nickels   +5 more
core   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source