Results 61 to 70 of about 2,097,328 (330)
Esub8: A novel tool to predict protein subcellular localizations in eukaryotic organisms
BMC Bioinformatics, 2004 Background Subcellular localization of a new protein sequence is very important and fruitful for understanding its function. As the number of new genomes has dramatically increased over recent years, a reliable and efficient system to predict protein ...
Liu Bing +3 more
doaj +1 more source
Differential Localization of G Protein βγ Subunits [PDF]
, 2014 G protein βγ subunits play essential roles in regulating cellular signaling cascades, yet little is known about their distribution in tissues or their subcellular localization.
Baucum, Anthony J. +6 more
core +1 more source
Frontiers in Genetics, 2019 Long non-coding RNAs (lncRNAs) play critical roles in various biological processes, but the function of the majority of lncRNAs is still unclear. One approach for estimating a function of a lncRNA is the identification of its interaction target because ...
Tsukasa Fukunaga +3 more
semanticscholar +1 more source
Assessing PTEN Subcellular Localization
, 2015 PTEN subcellular localization is fundamental in the execution of the distinct PTEN biological activities, including not only its PI(3,4,5)P3 phosphatase activity when associated to membranes but also its subcellular compartment-specific interactions with regulatory and effector proteins, including those exerted in the nucleus.
A. GIL, J. LOPEZ, R. PULIDO
openaire +6 more sources
Subcellular Localization of Copper [PDF]
, 2020 As an essential trace element, copper plays a pivotal role in physiological body functions. In fact, dysregulated copper homeostasis has been clearly linked to neurological disorders including Wilson and Alzheimer’s disease. Such neurodegenerative diseases are associated with progressive loss of neurons and thus impaired brain functions.
Witt, Barbara (Dr.) +2 more
+5 more sources
In Vivo Localization of Fas-Associated Death Domain Protein in the Nucleus and Cytoplasm of Normal Thyroid and Liver Cells [PDF]
, 2009 FADD (Fas-associated death domain) is the main death receptor adaptor molecule that transmits apoptotic signal. Recently, FADD protein was shown to be expressed both in the cytoplasm and nucleus of in vitro cell lines. In contrast to the cytoplasmic FADD,
Chiocchia, Gilles +2 more
core +5 more sources
Study of PTEN subcellular localization
Methods, 2015 The tumor suppressor PTEN is a key regulator of a plethora of cellular processes that are crucial in cancer development. Through its lipid phosphatase activity PTEN suppresses the PI3K/AKT pathway to govern cell proliferation, growth, migration, energy metabolism and death. The repertoire of roles fulfilled by PTEN has recently been expanded to include
BONONI, Angela, PINTON, Paolo
openaire +3 more sources
BaCelLo: a Balanced subCellular Localization predictor. [PDF]
Protocol Exchange, 2006 Abstract Motivation. The knowledge of the subcellular localization of a protein is fundamental for elucidating its function. It is difficult to determine the subcellular location for eukaryotic cells with experimental high-throughput procedures.
PIERLEONI, ANDREA +3 more
openaire +11 more sources
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Changes in Subcellular Localization of Host Proteins Induced by Plant Viruses
Viruses, 2021 Viruses are dependent on host factors at all parts of the infection cycle, such as translation, genome replication, encapsidation, and cell-to-cell and systemic movement.
Rosalba Rodriguez-Peña +2 more
doaj +1 more source