Results 41 to 50 of about 2,097,328 (330)
Subcellular localization of the five members of the human steroid 5α-reductase family [PDF]
, 2017 In humans the steroid 5a-reductase (SRD5A) family comprises five integral membrane enzymes that carry out reduction of a double bond in lipidic substrates: D4-3-keto steroids, polyprenol and trans-enoyl CoA.
Asteriti, ITALIA ANNA +10 more
core +3 more sources
Mathematics, 2023 Long non-coding RNAs (lncRNA) are a class of RNA transcripts with more than 200 nucleotide residues. LncRNAs play versatile roles in cellular processes and are thus becoming a hot topic in the field of biomedicine.
Jianyi Lyu +3 more
doaj +1 more source
Semi-automated curation of protein subcellular localization: a text mining-based approach to Gene Ontology (GO) Cellular Component curation [PDF]
, 2009 Background: Manual curation of experimental data from the biomedical literature is an expensive and time-consuming endeavor. Nevertheless, most biological knowledge bases still rely heavily on manual curation for data extraction and entry.
Chan, Juancarlos +4 more
core +4 more sources
Phospholipid subcellular localization and dynamics [PDF]
Journal of Biological Chemistry, 2018 Membrane biology seeks to understand how lipids and proteins within bilayers assemble into large structures such as organelles and the plasma membranes. Historically, lipids were thought to merely provide structural support for bilayer formation and membrane protein function.
Yanbo Yang, Minhyoung Lee, G. Fairn
semanticscholar +3 more sources
SnapShot: Subcellular mRNA Localization
Cell, 2017 Many cells localize mRNAs to discrete locations in the cytoplasm. Coupled to local translation, this process affords precise spatial and temporal control of protein function. This SnapShot provides an overview of the key events in subcellular mRNA localization and highlights recent progress in understanding how cytoskeletal motors orchestrate mRNA ...
Mohammad, Mofatteh, Simon L, Bullock
openaire +2 more sources
Sequence conserved for subcellular localization [PDF]
Protein Science, 2002 AbstractThe more proteins diverged in sequence, the more difficult it becomes for bioinformatics to infer similarities of protein function and structure from sequence. The precise thresholds used in automated genome annotations depend on the particular aspect of protein function transferred by homology. Here, we presented the first large‐scale analysis
Rajesh, Nair, Burkhard, Rost
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Predicting the subcellular localization of viral proteins within a mammalian host cell
Virology Journal, 2006 Background The bioinformatic prediction of protein subcellular localization has been extensively studied for prokaryotic and eukaryotic organisms. However, this is not the case for viruses whose proteins are often involved in extensive interactions at ...
Thomas DY, Oomen R, Scott MS, Hallett MT
doaj +1 more source
Frontiers in Genetics, 2021 Given the limitation of technologies, the subcellular localizations of proteins are difficult to identify. Predicting the subcellular localization and the intercellular distribution patterns of proteins in accordance with their specific biological roles,
Lei Chen +8 more
doaj +1 more source
Predicting multiplex subcellular localization of proteins using protein-protein interaction network: a comparative study [PDF]
, 2012 Background Proteins that interact in vivo tend to reside within the same or "adjacent" subcellular compartments. This observation provides opportunities to reveal protein subcellular localization in the context of the protein-protein interaction (PPI ...
Jonathan Q Jiang, Maoying Wu
core +2 more sources
Global Positioning System: Understanding Long Noncoding RNAs through Subcellular Localization.
Molecules and Cells, 2019 The localization of long noncoding RNAs (lncRNAs) within the cell is the primary determinant of their molecular functions. LncRNAs are often thought of as chromatin-restricted regulators of gene transcription and chromatin structure.
Joana Carlevaro-Fita, Rory Johnson
semanticscholar +1 more source