Results 41 to 50 of about 820,988 (298)

Recent Advances in the Prediction of Subcellular Localization of Proteins and Related Topics

Frontiers in Bioinformatics, 2022
Prediction of subcellular localization of proteins from their amino acid sequences has a long history in bioinformatics and is still actively developing, incorporating the latest advances in machine learning and proteomics.
Kenta Nakai, Leyi Wei
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ClubSub-P: Cluster-based subcellular localization prediction for Gram-negative bacteria and Archaea.

Frontiers in Microbiology, 2011
The subcellular localization of proteins provides important clues to their function in a cell. In our efforts to predict useful vaccine targets against Gram-negative bacteria, we noticed that misannotated start codons frequently lead to wrongly assigned ...
Nagarajan eParamasivam, Dirk eLinke
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Study of PTEN subcellular localization

Methods, 2015
The tumor suppressor PTEN is a key regulator of a plethora of cellular processes that are crucial in cancer development. Through its lipid phosphatase activity PTEN suppresses the PI3K/AKT pathway to govern cell proliferation, growth, migration, energy metabolism and death. The repertoire of roles fulfilled by PTEN has recently been expanded to include
BONONI, Angela, PINTON, Paolo
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Statistical analysis supports pervasive RNA subcellular localization and alternative 3' UTR regulation

eLife
Targeted low-throughput studies have previously identified subcellular RNA localization as necessary for cellular functions including polarization, and translocation.
Rob Bierman, Jui M Dave, Daniel M Greif, Julia Salzman   +3 more
doaj   +1 more source

Esub8: A novel tool to predict protein subcellular localizations in eukaryotic organisms

BMC Bioinformatics, 2004
Background Subcellular localization of a new protein sequence is very important and fruitful for understanding its function. As the number of new genomes has dramatically increased over recent years, a reliable and efficient system to predict protein ...
Liu Bing, Jiang Tianzi, Cui Qinghua, Ma Songde   +3 more
doaj   +1 more source

Reassessment of the subcellular localization of p63 [PDF]

Journal of Cell Science, 1995
ABSTRACT p63 is a type II integral membrane protein that has previously been suggested to be a resident protein of a membrane network interposed between the ER and the Golgi apparatus. In the present study, we have produced a polyclonal antibody against the purified human p63 protein to reassess the subcellular distribution of p63 by ...
A, Schweizer, J, Rohrer, J W, Slot, H J, Geuze, S, Kornfeld   +4 more
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Feature Fusion Based SVM Classifier for Protein Subcellular Localization Prediction

, 2016
For the importance of protein subcellular localization in different branches of life science and drug discovery, researchers have focused their attentions on protein subcellular localization prediction.
Ben Islam, Md Khaled, Mondal, Md Nazrul Islam, Al Mehedi, Md, Rahman, Julia   +3 more
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Subcellular localization and function study of a secreted phospholipase C from Nocardia seriolae [PDF]

, 2017
Fish nocardiosis is a chronic systemic granulomatous disease, andNocardia seriolaeis the main pathogen that causes this disease. But the pathogenesis and virulence factors ofN. seriolaeare not fully understood.
Honglian Zhang, Yishan Lu, Xia, Liqin, Michaël Bekaert, Haiying Liang, Liang Xu, Bekaert, Michaël, Liqun Xia, Liang, Haiying, Zhang, Honglian, Jianlin Chen, Chen, Jianlin, Xu, Liang, Yu, Lishan   +13 more
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Subcellular localization of the yeast proteome [PDF]

Genes & Development, 2002
Protein localization data are a valuable information resource helpful in elucidating eukaryotic protein function. Here, we report the first proteome-scale analysis of protein localization within any eukaryote. Using directed topoisomerase I-mediated cloning strategies and genome-wide transposon mutagenesis, we have epitope-tagged ...
Anuj, Kumar, Seema, Agarwal, John A, Heyman, Sandra, Matson, Matthew, Heidtman, Stacy, Piccirillo, Lara, Umansky, Amar, Drawid, Ronald, Jansen, Yang, Liu, Kei-Hoi, Cheung, Perry, Miller, Mark, Gerstein, G Shirleen, Roeder, Michael, Snyder   +14 more
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Sequence analysis and subcellular localization of crucian carp Carassius auratus viperin

, 2014
Human viperin is known as an interferon (IFN)-inducible antiviral protein and localizes to endoplasmic reticulum (ER) via its N-terminal amphipathic alpha-helix. Little is known about subcellular localization of fish viperin.
Zhang, Yi-Bing, Wang, Bing, Gui, Jian-Fang, Liu, Ting-Kai   +3 more
core   +1 more source