Gm-PLoc: A Subcellular Localization Model of Multi-Label Protein Based on GAN and DeepFM
Identifying the subcellular localization of a given protein is an essential part of biological and medical research, since the protein must be localized in the correct organelle to ensure physiological function.
Liwen Wu +14 more
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Application of RNA subcellular fraction estimation method to explore RNA localization regulation
RNA localization is involved in multiple biological processes. Recent advances in subcellular fractionation-based sequencing approaches uncovered localization pattern on a global scale. Most of existing methods adopt relative localization ratios (such as
Xiaomin Dai +8 more
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Classification and subcellular localization analysis.
(A) Biological processes classification. (B) Molecular function classification. (C) Cellular component classification. (D) Subcellular localization.
Lijuan Sun (1644832) +1 more
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Subcellular localization prediction of the shortlisted proteins.
Subcellular localization prediction of the shortlisted proteins.
Abbas Ahmad (16517912) +9 more
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Tissue- and developmental stage-specific changes in the subcellular localization of the 26S proteasome in the ovary of Drosophila melanogaster [PDF]
The intracellular localization of the 26S proteasome in the different ovarian cell types of Drosophila melanogaster was studied by means of immunofluorescence staining and laser scanning microscopy, with the use of antibodies specific for regulatory ...
Andó, István +5 more
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DBMLoc: a Database of proteins with multiple subcellular localizations
Background Subcellular localization information is one of the key features to protein function research. Locating to a specific subcellular compartment is essential for a protein to function efficiently.
Zhou Yun +4 more
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Prediction of protein localization plays an important role in understanding protein function and mechanisms. In this paper, we propose a general deep learning-based localization prediction framework, MULocDeep, which can predict multiple localizations of
Yuexu Jiang +6 more
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Protein localization as a principal feature of the etiology and comorbidity of genetic diseases
Proteins targeting the same subcellular localization tend to participate in mutual protein–protein interactions (PPIs) and are often functionally associated. Here, we investigated the relationship between disease‐associated proteins and their subcellular
Solip Park +5 more
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Quantitative protein localization signatures reveal an association between spatial and functional divergences of proteins. [PDF]
Protein subcellular localization is a major determinant of protein function. However, this important protein feature is often described in terms of discrete and qualitative categories of subcellular compartments, and therefore it has limited applications
Lit-Hsin Loo +2 more
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Multi-label multi-kernel transfer learning for human protein subcellular localization. [PDF]
Recent years have witnessed much progress in computational modelling for protein subcellular localization. However, the existing sequence-based predictive models demonstrate moderate or unsatisfactory performance, and the gene ontology (GO) based models ...
Suyu Mei
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