MicroRNA maturation: stepwise processing and subcellular localization
EMBO Journal, 2002 Kipyoung Jeon
exaly +2 more sources
Identification of Protein Subcellular Localization With Network and Functional Embeddings
Frontiers in Genetics, 2021 The functions of proteins are mainly determined by their subcellular localizations in cells. Currently, many computational methods for predicting the subcellular localization of proteins have been proposed.
Xiaoyong Pan +6 more
semanticscholar +1 more source
Subcellular Localization of CIAPIN1 [PDF]
Journal of Histochemistry & Cytochemistry, 2006 Cytokine-induced apoptosis inhibitor 1 (CIAPIN1) is a newly identified anti-apoptotic molecule. Our previous studies have demonstrated that CIAPIN1 is ubiquitously expressed in normal fetal and adult human tissues and confers multidrug resistance in gastric cancer cells, possibly by upregulating the expression of multidrug resistance gene 1 and ...
Zhiming, Hao +5 more
openaire +2 more sources
Application of RNA subcellular fraction estimation method to explore RNA localization regulation
G3: Genes, Genomes, Genetics, 2021 RNA localization is involved in multiple biological processes. Recent advances in subcellular fractionation-based sequencing approaches uncovered localization pattern on a global scale. Most of existing methods adopt relative localization ratios (such as
Xiaomin Dai +8 more
doaj +1 more source
eSLDB: eukaryotic subcellular localization database [PDF]
Nucleic Acids Research, 2007 Eukaryotic Subcellular Localization DataBase collects the annotations of subcellular localization of eukaryotic proteomes. So far five proteomes have been processed and stored: Homo sapiens, Mus musculus, Caenorhabditis elegans, Saccharomyces cerevisiae and Arabidopsis thaliana. For each sequence, the database lists localization obtained adopting three
PIERLEONI, ANDREA +3 more
openaire +5 more sources
GAP activity, but not subcellular targeting, is required for Arabidopsis RanGAP cellular and developmental functions [PDF]
, 2015 The Ran GTPase activating protein (RanGAP) is important to Ran signaling involved in nucleocytoplasmic transport, spindle organization, and postmitotic nuclear assembly.
Boruc, Joanna +6 more
core +2 more sources
Computational and Structural Biotechnology Journal, 2021 Prediction of protein localization plays an important role in understanding protein function and mechanisms. In this paper, we propose a general deep learning-based localization prediction framework, MULocDeep, which can predict multiple localizations of
Yuexu Jiang +6 more
doaj +1 more source
DBMLoc: a Database of proteins with multiple subcellular localizations
BMC Bioinformatics, 2008 Background Subcellular localization information is one of the key features to protein function research. Locating to a specific subcellular compartment is essential for a protein to function efficiently.
Zhou Yun +4 more
doaj +1 more source
Different domains cooperate to target the human ribosomal L7a protein to the nucleus and to the nucleoli. [PDF]
, 1997 The human ribosomal protein L7a is a component of the major ribosomal subunit. We transiently expressed in HeLa cells L7a-β-galactosidase fusion proteins and studied their subcellular localization by indirect immunofluorescence staining with anti-β ...
Giulia RUSSO +2 more
core +1 more source
Quantitative protein localization signatures reveal an association between spatial and functional divergences of proteins. [PDF]
PLoS Computational Biology, 2014 Protein subcellular localization is a major determinant of protein function. However, this important protein feature is often described in terms of discrete and qualitative categories of subcellular compartments, and therefore it has limited applications
Lit-Hsin Loo +2 more
doaj +1 more source