Results 21 to 30 of about 855,524 (247)

Gm-PLoc: A Subcellular Localization Model of Multi-Label Protein Based on GAN and DeepFM

open access: yesFrontiers in Genetics, 2022
Identifying the subcellular localization of a given protein is an essential part of biological and medical research, since the protein must be localized in the correct organelle to ensure physiological function.
Liwen Wu   +14 more
doaj   +1 more source

Application of RNA subcellular fraction estimation method to explore RNA localization regulation

open access: yesG3: Genes, Genomes, Genetics, 2021
RNA localization is involved in multiple biological processes. Recent advances in subcellular fractionation-based sequencing approaches uncovered localization pattern on a global scale. Most of existing methods adopt relative localization ratios (such as
Xiaomin Dai   +8 more
doaj   +1 more source

Classification and subcellular localization analysis.

open access: yes, 2021
(A) Biological processes classification. (B) Molecular function classification. (C) Cellular component classification. (D) Subcellular localization.
Lijuan Sun (1644832)   +1 more
core   +1 more source

Subcellular localization prediction of the shortlisted proteins.

open access: yes, 2023
Subcellular localization prediction of the shortlisted proteins.
Abbas Ahmad (16517912)   +9 more
core   +1 more source

Tissue- and developmental stage-specific changes in the subcellular localization of the 26S proteasome in the ovary of Drosophila melanogaster [PDF]

open access: yes, 2004
The intracellular localization of the 26S proteasome in the different ovarian cell types of Drosophila melanogaster was studied by means of immunofluorescence staining and laser scanning microscopy, with the use of antibodies specific for regulatory ...
Andó, István   +5 more
core   +1 more source

DBMLoc: a Database of proteins with multiple subcellular localizations

open access: yesBMC Bioinformatics, 2008
Background Subcellular localization information is one of the key features to protein function research. Locating to a specific subcellular compartment is essential for a protein to function efficiently.
Zhou Yun   +4 more
doaj   +1 more source

MULocDeep: A deep-learning framework for protein subcellular and suborganellar localization prediction with residue-level interpretation

open access: yesComputational and Structural Biotechnology Journal, 2021
Prediction of protein localization plays an important role in understanding protein function and mechanisms. In this paper, we propose a general deep learning-based localization prediction framework, MULocDeep, which can predict multiple localizations of
Yuexu Jiang   +6 more
doaj   +1 more source

Protein localization as a principal feature of the etiology and comorbidity of genetic diseases

open access: yesMolecular Systems Biology, 2011
Proteins targeting the same subcellular localization tend to participate in mutual protein–protein interactions (PPIs) and are often functionally associated. Here, we investigated the relationship between disease‐associated proteins and their subcellular
Solip Park   +5 more
doaj   +1 more source

Quantitative protein localization signatures reveal an association between spatial and functional divergences of proteins. [PDF]

open access: yesPLoS Computational Biology, 2014
Protein subcellular localization is a major determinant of protein function. However, this important protein feature is often described in terms of discrete and qualitative categories of subcellular compartments, and therefore it has limited applications
Lit-Hsin Loo   +2 more
doaj   +1 more source

Multi-label multi-kernel transfer learning for human protein subcellular localization. [PDF]

open access: yesPLoS ONE, 2012
Recent years have witnessed much progress in computational modelling for protein subcellular localization. However, the existing sequence-based predictive models demonstrate moderate or unsatisfactory performance, and the gene ontology (GO) based models ...
Suyu Mei
doaj   +1 more source

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