Results 11 to 20 of about 2,097,328 (330)

Refining protein subcellular localization. [PDF]

PLoS Computational Biology, 2005
The study of protein subcellular localization is important to elucidate protein function. Even in well-studied organisms such as yeast, experimental methods have not been able to provide a full coverage of localization.
Michelle S Scott, Sara J Calafell, David Y Thomas, Michael T Hallett   +3 more
doaj   +5 more sources

Semi-supervised protein subcellular localization [PDF]

BMC Bioinformatics, 2009
Background Protein subcellular localization is concerned with predicting the location of a protein within a cell using computational method. The location information can indicate key functionalities of proteins.
Xue Hong, Hu Derek, Xu Qian, Yu Weichuan, Yang Qiang   +4 more
doaj   +4 more sources

A review from biological mapping to computation-based subcellular localization

Molecular Therapy: Nucleic Acids, 2023
Subcellular localization is crucial to the study of virus and diseases. Specifically, research on protein subcellular localization can help identify clues between virus and host cells that can aid in the design of targeted drugs.
Jing Li, Quan Zou, Lei Yuan
doaj   +1 more source

The Subcellular Localization of RRAGD.

Journal of the American Society of Nephrology, 2022
Tiantian Ma, Lei Zhang, Limeng Chen
semanticscholar   +3 more sources

Gm-PLoc: A Subcellular Localization Model of Multi-Label Protein Based on GAN and DeepFM

Frontiers in Genetics, 2022
Identifying the subcellular localization of a given protein is an essential part of biological and medical research, since the protein must be localized in the correct organelle to ensure physiological function.
Liwen Wu, Liwen Wu, Song Gao, Song Gao, Shaowen Yao, Shaowen Yao, Feng Wu, Feng Wu, Jie Li, Jie Li, Yunyun Dong, Yunyun Dong, Yunqi Zhang, Yunqi Zhang, Yunqi Zhang   +14 more
doaj   +1 more source

DeepLoc 2.0: multi-label subcellular localization prediction using protein language models

Nucleic Acids Res., 2022
The prediction of protein subcellular localization is of great relevance for proteomics research. Here, we propose an update to the popular tool DeepLoc with multi-localization prediction and improvements in both performance and interpretability.
Vineet Thumuluri, J. J. Almagro Armenteros, alexander rosenberg johansen, Henrik Nielsen, Ole Winther   +4 more
semanticscholar   +1 more source

System-wide analysis of RNA and protein subcellular localization dynamics

Nature Methods, 2023
An integrative framework to simultaneously interrogate the dynamics of the transcriptome and proteome at subcellular resolution that combines two methods, localization of RNA (LoRNA) and a streamlined density-based localization of proteins by isotope ...
E. Villanueva, Tom S. Smith, Mariavittoria Pizzinga, Mohamed A. W. Elzek, R. Queiroz, Robert F. Harvey, L. Breckels, Oliver M. Crook, Mie Monti, Veronica Dezi, A. Willis, Kathryn S. Lilley   +11 more
semanticscholar   +1 more source

DM3Loc: multi-label mRNA subcellular localization prediction and analysis based on multi-head self-attention mechanism

Nucleic Acids Research, 2021
Subcellular localization of messenger RNAs (mRNAs), as a prevalent mechanism, gives precise and efficient control for the translation process.
Duolin Wang, Zhao-Yue Zhang, Yuexu Jiang, Z. Mao, Dong Wang, Hao Lin, Dong Xu   +6 more
semanticscholar   +1 more source

RNALocate v2.0: an updated resource for RNA subcellular localization with increased coverage and annotation

Nucleic Acids Res., 2021
Resolving the spatial distribution of the transcriptome at a subcellular level can increase our understanding of biology and diseases. To facilitate studies of biological functions and molecular mechanisms in the transcriptome, we updated RNALocate, a ...
Tianyu Cui, Yiying Dou, Puwen Tan, Z. Ni, Tianyuan Liu, Duolin Wang, Yan Huang, K. Cai, Xiaoyang Zhao, Dong Xu, Hao Lin, Dong Wang   +11 more
semanticscholar   +1 more source

RNAlight: a machine learning model to identify nucleotide features determining RNA subcellular localization

bioRxiv, 2022
Different RNAs have distinct subcellular localizations. However, nucleotide features that determine these distinct distributions of lncRNAs and mRNAs have yet to be fully addressed.
Guoliang Yuan, Ying Wang, Guang-Zhong Wang, Li Yang   +3 more
semanticscholar   +1 more source