Results 11 to 20 of about 820,988 (298)
Prediction of protein subcellular localization using support vector machine with the choice of proper kernel [PDF]
BioTechnologia, 2017 The prediction of subcellular locations of proteins can provide useful hints for revealing their functions as well as for understanding the mechanisms of some diseases and, finally, for developing novel drugs.
Al Mehedi Hasan +2 more
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Semi-supervised protein subcellular localization [PDF]
BMC Bioinformatics, 2009 Background Protein subcellular localization is concerned with predicting the location of a protein within a cell using computational method. The location information can indicate key functionalities of proteins.
Xue Hong +4 more
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eSLDB: eukaryotic subcellular localization database [PDF]
Nucleic Acids Research, 2007 Eukaryotic Subcellular Localization DataBase collects the annotations of subcellular localization of eukaryotic proteomes. So far five proteomes have been processed and stored: Homo sapiens, Mus musculus, Caenorhabditis elegans, Saccharomyces cerevisiae and Arabidopsis thaliana. For each sequence, the database lists localization obtained adopting three
PIERLEONI, ANDREA +3 more
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Unified mRNA Subcellular Localization Predictor based on machine learning techniques
BMC GenomicsBackground The mRNA subcellular localization bears substantial impact in the regulation of gene expression, cellular migration, and adaptation. However, the methods employed for experimental determination of this localization are arduous, time-intensive,
Saleh Musleh +3 more
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BaCelLo: a Balanced subCellular Localization predictor. [PDF]
Protocol Exchange, 2006 Abstract Motivation. The knowledge of the subcellular localization of a protein is fundamental for elucidating its function. It is difficult to determine the subcellular location for eukaryotic cells with experimental high-throughput procedures.
PIERLEONI, ANDREA +3 more
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Decoding subcellular RNA localization one molecule at a time
Genome BiologyEukaryotic cells are highly structured and composed of multiple membrane-bound and membraneless organelles. Subcellular RNA localization is a critical regulator of RNA function, influencing various biological processes.
Josep Biayna, Gabrijela Dumbović
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DBSubLoc: database of protein subcellular localization [PDF]
Nucleic Acids Research, 2004 We have built a protein subcellular localization annotation database, the DBSubLoc database, which is available at http://www.bioinfo.tsinghua. edu.cn/dbsubloc.html. Annotations were taken from primary protein databases, model organism genome projects and literature texts, and then were analyzed to dig out the subcellular localization features of the ...
Tao Guo +3 more
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Threonine 348 regulates the subcellular localization of PTEN. [PDF]
FEBS Open BioThr348 in the C2 domain is a key contributor to PTEN subcellular localization. The PTEN350 fragment and PTENA4 accumulated in the nucleus, whereas PTENK13R,A4 predominantly localized to the plasma membrane. In contrast, substitution of Thr348 with Asp (T348D) disrupted these characteristic localization patterns, resulting in predominant cytoplasmic ...
Kato T, Tanaka S, Ohashi M.
europepmc +2 more sources
Paeans/subcellular: Subcellular localization
, 2021 First release of protein subcellular location prediction ...
Pan Gaofeng
core +1 more source
Tissue- and developmental stage-specific changes in the subcellular localization of the 26S proteasome in the ovary of Drosophila melanogaster [PDF]
, 2004 The intracellular localization of the 26S proteasome in the different ovarian cell types of Drosophila melanogaster was studied by means of immunofluorescence staining and laser scanning microscopy, with the use of antibodies specific for regulatory ...
Andó, István +5 more
core +1 more source