Recent advances in imaging subcellular processes [version 1; referees: 2 approved] [PDF]
F1000Research, 2016 Cell biology came about with the ability to first visualize cells. As microscopy techniques advanced, the early microscopists became the first cell biologists to observe the inner workings and subcellular structures that control life. This ability to see
Kenneth A. Myers +1 more
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Imaging cell membrane injury and subcellular processes involved in repair. [PDF]
J Vis Exp, 2014 The ability of injured cells to heal is a fundamental cellular process, but cellular and molecular mechanisms involved in healing injured cells are poorly understood. Here assays are described to monitor the ability and kinetics of healing of cultured cells following localized injury.
Defour A, Sreetama SC, Jaiswal JK.
europepmc +5 more sources
Probing the spatiotemporal patterns of HBV multiplication reveals novel features of its subcellular processes. [PDF]
PLoS Pathogens, 2021 Through evolution, Hepatitis B Virus (HBV) developed highly intricate mechanisms exploiting host resources for its multiplication within a constrained genetic coding capacity.
Lei Yue +7 more
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LAFITE Reveals the Complexity of Transcript Isoforms in Subcellular Fractions
Advanced Science, 2023 Characterization of the subcellular distribution of RNA is essential for understanding the molecular basis of biological processes. Here, the subcellular nanopore direct RNA‐sequencing (DRS) of four lung cancer cell lines (A549, H1975, H358, and HCC4006)
Jizhou Zhang +7 more
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Editorial: The subcellular architecture of mitochondria in driving cellular processes
Frontiers in Cell and Developmental Biology, 2022 Brian Cunniff +2 more
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Predicting circRNA subcellular localization by fusing circRNA sequence and network information [PDF]
Scientific ReportsCircRNAs have attracted more and more attentions in recent years as they play important roles in many biological processes. It is essential for determining the functions of circRNAs.
Lei Chen, Jinghai Hu, Bo Zhou
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Cell Reports, 2021 Summary: We present a sheathless, microfluidic imaging flow cytometer that incorporates stroboscopic illumination for blur-free fluorescence detection at ultra-high analytical throughput.
Gregor Holzner +6 more
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Protein Kinase A in cellular migration—Niche signaling of a ubiquitous kinase
Frontiers in Molecular Biosciences, 2022 Cell migration requires establishment and maintenance of directional polarity, which in turn requires spatial heterogeneity in the regulation of protrusion, retraction, and adhesion.
Kathryn V. Svec +3 more
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Characterization of PINK1 processing, stability, and subcellular localization [PDF]
Journal of Neurochemistry, 2008 AbstractMutations found in PTEN‐induced putative kinase 1 (PINK1), a putative mitochondrial serine/threonine kinase of unknown function, have been linked to autosomal recessive Parkinson’s disease. It is suggested that mutations can cause a loss of PINK1 kinase activity and eventually lead to mitochondrial dysfunction.
William, Lin, Un Jung, Kang
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MicroRNA maturation: stepwise processing and subcellular localization [PDF]
The EMBO Journal, 2002 MicroRNAs (miRNAs) constitute a novel, phylogenetically extensive family of small RNAs ( approximately 22 nucleotides) with potential roles in gene regulation. Apart from the finding that miRNAs are produced by Dicer from the precursors of approximately 70 nucleotides (pre-miRNAs), little is known about miRNA biogenesis.
Yoontae, Lee +4 more
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