Results 131 to 140 of about 191,821 (303)

Mechanism‐Driven Nanoformulations for Cognitive Impairment Induced by Intermittent Hypoxia and Periodontitis

Advanced Materials, EarlyView.
Clinically, intermittent hypoxia (IH) is often accompanied by periodontitis, which accelerates cognitive impairment induced by IH. Novel Janus mesoporous gold‐silica nanoformulations (RVG‐Au&mSiO2‐TPP‐VB) enable intranasal delivery, achieve hierarchical targeting to neuronal mitochondria, effectively scavenge reactive oxygen species, inhibit the HIF‐1α/
Kai‐Run Zhang, Tianbao Zhu, An‐Qi Liu, Jia‐Jia Deng, Ya‐Li Han, Sheng‐Cai Qi, Xue Liu, Tian‐Yi Jiang, Ming‐Rui Zhai, Yu‐Ying He, Xiu‐Juan Li, Hong‐Ting Da, Rui Xu, Xiaomin Li, Jun Gao, Yue‐Hua Liu   +15 more
wiley   +1 more source

In silico evaluation of arrhythmia

, 2017
Iteration between computational and experimental physiology has largely contributed to expanding scientific knowledge in cardiovascular research over the last decades.
Rodriguez, Blanca, Alfonso Bueno-Orovio, Rodriguez, B, Bueno Orovio, Alfonso, Zhou, X, Zhou, Xin, Bueno Orovio, A, Blanca Rodriguez, Xin Zhou   +8 more
core   +2 more sources

Negotiating in a Foreign Land: Understanding the Curious Interactions Between Intracellular Mitochondria and Internalized Nanoparticles

Advanced Materials Interfaces, EarlyView.
Therapeutic nano‐drug delivery systems interact with cellular mitochondria in a multitude of ways. While the complexity of such interactions disrupts the mitochondrial electron transport chain and increases reactive oxygen species production, thereby contributing to nanoparticle toxicity, they also present unique theranostic opportunities in diseases ...
Sourav Bhattacharjee
wiley   +1 more source

Cellular Microrheology

A multitude of cellular and subcellular processes with pathological relevance depend critically on the mechanical deformability of the cytoplasm. Particle-tracking microrheology measures the viscoelastic properties of the cytoplasm locally and with high ...
García De Herreros Dunyac, Antoni
core  

A Reproducible and Scalable Process for High Yield Mesenchymal Stromal Cell Extracellular Vesicles Production

Advanced Materials Technologies, EarlyView.
Mesenchymal stem cell derived extracellular vesicles (MSC‐EVs) are a promising therapeutic tool for regenerative medicine. However, the field lacks a reproducible high‐yield production method to answer the quantities needed for clinical translation.
Christophe Wong, Elise Madec, Jeanne Volatron, Max Piffoux, Amanda K. A. Silva, Florence Gazeau, Jean‐Philippe Herbeuval, Thibaut Fourniols   +7 more
wiley   +1 more source

3-AMINOBENZAMIDE INDUCES CYTOSKELETON REARRANGEMENT IN M14 MELANOMA-CELLS

, 1994
3-aminobenzamide (3-ABA) is an inhibitor of poly-ADP-ribose-polymerase, an enzyme involved in numerous subcellular processes including cell death. With the aim of contributing to clarify the mode of action of the drug, which is still poorly understood ...
Rainaldi G., MONTI D, FRANCESCHI C., Straface E., CAPRI M, STRAFACE E, COSSARIZZA, Andrea, Rivabene R., RAINALDI G, Cossarizza A., Capri M., RIVABENE R, MALORNI W, Malorni W., Monti D.   +14 more
core   +1 more source

Non-coding RNAs and a layered architecture of genetic networks

Open Physics, 2010
Zhdanov Vladimir
doaj   +1 more source

Subcellular Process [PDF]

, 2020
openaire   +1 more source

From Lab to Landscape: Environmental Biohybrid Robotics for Ecological Futures

Advanced Robotics Research, EarlyView.
This Perspective explores environmental biohybrid robotics, integrating living tissues, microorganisms, and insects for operation in real‐world ecosystems. It traces the leap from laboratory experiments to forests, wetlands, and urban environments and discusses key challenges, development pathways, and opportunities for ecological monitoring and ...
Miriam Filippi
wiley   +1 more source

A generic 3D kinetic model of gene expression

Open Physics, 2012
Zhdanov Vladimir
doaj   +1 more source