Results 11 to 20 of about 558,914 (188)

Essential oil of Ageratum conyzoides (L.) L.: Acute and subchronic toxicity studies [PDF]

Journal of Pharmacy & Pharmacognosy Research, 2023
Context: The essential oil of the Ageratum conyzoides (100 mg/kg BW) previously demonstrated anti-neuropathic pain activity with various mechanisms of action. However, the safety data of this essential oil is unknown.
I Ketut Adnyana, Kusnandar Anggadiredja, Yedy Purwandi Sukmawan   +2 more
doaj   +3 more sources

Acute and Subchronic Toxicity of Indonesian House Dust Mites (IHDM) Allergenic Extract for Asthma Allergy Immunotherapy [PDF]

Jurnal Farmasi dan Ilmu Kefarmasian Indonesia, 2022
Background: In developing a pharmaceutical product, it is necessary to conduct pre-clinical and clinical trials to ensure its safety and effectiveness.
Aniek Setiya Budiatin, Yusuf Alif Pratama, Winda Fatma Sari, Mahardian Rahmadi, Muhammad Taher, Zainul Amiruddin Zakaria, Junaidi Khotib   +6 more
doaj   +3 more sources

Safety evaluation of ethanol extract from Artocarpus altilis leaves as a herbal medicine candidate: Studies in acute and subchronic toxicity

Phytomedicine Plus
Background: Artocarpus altilis is a traditional medicine proven to be efficacious in several pharmacological tests using animal models. However, there have been no reports regarding its safety so far.
Fitrya Fitrya, Elfita Elfita, Ferlinahayati, Salma Fayzah Septami, Umi Tsalsa Sabrina, Fatma Sri Wahyuni, Annisa Amriani, Rennie Puspa Novita   +7 more
doaj   +2 more sources

Subchronic toxicity of silica nanoparticles as a function of size and porosity [PDF]

Journal of Controlled Release, 2019
Despite increasing reports of using silica nanoparticles (SNPs)for controlled drug delivery applications, their long-term toxicity profile following intravenous administration remains unexplored.
Mostafa Yazdimamaghani, Raziye Mohammadpour, Hamidreza Ghandehari   +2 more
exaly   +3 more sources

Acute and subchronic oral toxicity studies of hydrogenated curcuminoid formulation ‘CuroWhite’ in rats

Toxicology Reports, 2016
Hydrogenated curcuminoids are the major metabolites of the curcumin and ‘CuroWhite’ is a unique blend of hydrogenated curcuminoids encapsulated with β-cyclodextrin.
Sreeraj Gopi, Joby Jacob, Kotrappa Y. Mathur   +2 more
doaj   +2 more sources

Acute, Subchronic, and Genetic Toxicity Assessments of a Composition of Citrus aurantifolia Fruit Rind and Theobroma cacao Seed Extracts

Journal of Toxicology
LN19183 is a standardized composition of Citrus aurantifolia (Christm) Swingle (CA) fruit rind and Theobroma cacao L. (TC) seed extracts that have recently been demonstrated to increase resting energy expenditure (REE) and reduce body fat in rats. CA and
Sundararaju Dodda, Sujatha Polavarapu, Krishnaraju Venkata Alluri, Trimurtulu Golakoti, Krishanu Sengupta   +4 more
doaj   +2 more sources

Subchronic Toxicity Study of Oral Anthrafuran on Rabbits. [PDF]

Pharmaceuticals (Basel), 2021
A new antitumor multi-target drug anthrafuran, with cellular targets such as topoisomerase I/II and some protein kinases, was obtained in Gause Institute of New Antibiotics and was demonstrated to have a reliable specific effect on different murine and ...
Treshchalin MI, Treshalina HM, Golibrodo VA, Shchekotikhin AE, Pereverzeva ER.   +4 more
europepmc   +2 more sources

Biochemical analyses of rats in 13-week subchronic toxicity study.

, 2023
Biochemical analyses of rats in 13-week subchronic toxicity study.
Xin Li (51274), Shengcan Zou (17181432), Yuanyuan Wang (20181), Zimin Liu (10509550), Dehai Gao (17181435), Yanling Mu (4737747), Shanglong Wang (12045182), Jiancheng Zong (12045185), Li Li (14993)   +8 more
core   +1 more source

Hematological parameters for rats in 13-week subchronic toxicity study.

, 2023
Hematological parameters for rats in 13-week subchronic toxicity study.
Xin Li (51274), Shengcan Zou (17181432), Yuanyuan Wang (20181), Zimin Liu (10509550), Dehai Gao (17181435), Yanling Mu (4737747), Shanglong Wang (12045182), Jiancheng Zong (12045185), Li Li (14993)   +8 more
core   +1 more source

Safety assessment of subtilisin QK in rats

BMC Pharmacology and Toxicology, 2021
Background Subtilisin QK is a serine protease in the subtilisin family, and is fermented by Bacillus subtilis QK02. The fibrinolytic activity of subtilisin QK was measured by detecting low molecular weight degradation products using a spectrophotometric ...
Shuai Xiao, Dingbang Hu, Ya Gao, Yang Ai, Sang Luo, Song Chen, Ben Wang, Li Zhou, Yanshan Dong, Yefu Wang   +9 more
doaj   +1 more source