Results 11 to 20 of about 98,117 (335)
Advances in Nanoparticulate Drug Delivery Approaches for Sublingual and Buccal Administration
Frontiers in Pharmacology, 2019 The sublingual and buccal routes of administration have significant advantages for both local and systemic drug delivery. They have shown to be an effective alternative to the traditional oral route, especially when fast onset of action is required ...
Susan Hua, Susan Hua
doaj +2 more sources
Microenvironmental pH Modification in Buccal/Sublingual Dosage Forms for Systemic Drug Delivery
Pharmaceutics, 2023 Many drug candidates are poorly water-soluble. Microenvironmental pH (pHM) modification in buccal/sublingual dosage forms has attracted increasing interest as a promising pharmaceutical strategy to enhance the oral mucosal absorption of drugs with pH ...
Shaolong He, H. Mu
semanticscholar +1 more source
Arthritis care & research, 2023 To evaluate the efficacy and safety of TNX‐102 SL, a once‐nightly sublingual formulation of cyclobenzaprine, in reducing pain in patients with fibromyalgia (FM).
S. Lederman +4 more
semanticscholar +1 more source
Journal of the American Medical Association (JAMA), 2022 Importance Acute agitation is common in patients with bipolar disorder and requires urgent management to relieve distress and to prevent escalation to aggressive behavior. Objective To evaluate the effect of orally absorbed, sublingual dexmedetomidine,
S. Preskorn +9 more
semanticscholar +1 more source
JAMA Network Open, 2021 Key Points Question Are patient-reported outcomes, such as treatment satisfaction with medication, higher among patients treated with weekly and monthly subcutaneous buprenorphine depot formulations vs daily sublingual buprenorphine?
N. Lintzeris +11 more
semanticscholar +1 more source
JAMA Network Open, 2021 Key Points Question Is extended-release buprenorphine an acceptable and helpful jail-to-community treatment option among adults already receiving daily sublingual buprenorphine for opioid use disorders? Findings In this pilot proof-of-concept comparative
Joshua D. Lee +13 more
semanticscholar +1 more source
Sublingual vaccination and delivery systems.
Journal of Controlled Release, 2021 Most infectious agents use mucosal tissues as entry portals, thus, mucosae are frequently defined as a first line of defense against pathogens. Mucosal protection generally operates through antibody-mediated and cytotoxic T-cell responses which can be ...
A. Paris +4 more
semanticscholar +1 more source
Sublingual protein delivery by a mucoadhesive patch made of natural polymers.
Acta Biomaterialia, 2021 The sublingual mucosa is an appealing route for drug administration. However, in the context of increased use of therapeutic proteins, development of protein delivery systems that will protect the protein bioactivity is needed.
A. Paris +6 more
semanticscholar +1 more source
Frontiers in Immunology, 2020 Application of allergens onto the sublingual epithelium is used to desensitize allergic individuals, a treatment known as sublingual immunotherapy. However, the response of sublingual epithelial cells to house dust mite allergen and potential tolerance ...
Michael P. Pelst +8 more
doaj +1 more source
Silodosin oral films: Development, physico-mechanical properties and in vitro dissolution studies in simulated saliva [PDF]
, 2019 Sublingual film dosage forms for drugs used for fast symptomatic treatment have promise because they allow a rapid onset of action. The aim of this study was to prepare films of silodosin intended for sublingual administration for the symptomatic ...
Adair +57 more
core +2 more sources