Results 131 to 140 of about 2,947,412 (335)

A cross‐national study on adolescent substance use: Intentions, peer substance use, and parent‐adolescent communication [PDF]

, 2023
Ivy N. Defoe, Judith Semon Dubas, Marcel A. G. van Aken   +2 more
openalex   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Integration of circadian and hypoxia signaling via non‐canonical heterodimerization

FEBS Letters, EarlyView.
CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

FEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

A Matter of Substance, August 2010. [PDF]

, 2010
A publication of the IDPH Division of Behavioral Health to find out what's happening with Substance Abuse Prevention and ...

core  

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Aspects Cliniques et Thérapeutiques des Pertes de Substances Mandibulaires Balistiques en Milieu de Conflits Armés à Mopti (Mali)

Health Research in Africa
RESUME Introduction. Au Mali, les traumatismes balistiques responsables de pertes de substances mandibulaires, sont souvent causés par une tentative d'autolyse, une agression ou un accident. Le but de notre travail est d’étudier les aspects cliniques et
Théra Thioukany David, Fofana Youssouf, Koné Mory, Guindo Aly Abdoulaye, Sidibé Lamine, Traoré Bréhima, Guindo Oumar, Cissé Dramane, Coulibaly Amady   +8 more
doaj   +1 more source

Supporting Information from The Next Frontier of Environmental Unknowns: Substances of Unknown or Variable Composition, Complex Reaction Products, or Biological Materials (UVCBs)

, 2023
Lai Adelene
openalex   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

Формування предметного поля метафізичних категорій у просторі філософських ідей Пізньої схоластики / The Formation of the Subject Field of Metaphysical Categories in Terms of Philosophical Ideas of Late Scholastic

Актуальні питання суспільних наук та історії медицини, 2014
Skrytska Natalya. The Formation of the Subject Field of Metaphysical Categories in Terms of Philosophical Ideas of Late Scholastics. The article considers the nature of such metaphysical concepts as essence, being, God, substance, logical quantifier ...
Скрицька Наталія
doaj