Results 121 to 130 of about 841,730 (362)

Hemp Proteins Conjugated with Green Tea Polyphenol Extract Form De Novo Plant‐Sourced Emulsifiers Suitable for Nanodelivery Systems Bearing Lipophilic Psychopharmaceuticals

open access: yesAdvanced Therapeutics, EarlyView.
Green tea polyphenols, conjugated either covalently or non‐covalently to hemp protein, comprise an excellent stabilizing matrix for oxidatively‐sensitive small molecules. These nanoemulsions are highly stable to a variety of chemical and physical stressors, protecting the small molecule while allowing for easy uptake across cell membranes and rapid ...
William Charles Hosie   +9 more
wiley   +1 more source

Drugs and Growth-Efficient Prevention: An Inter-temporal Portfolio of Machos, Narcos and Angels [PDF]

open access: yes
In many countries substance abuse is a social epidemic. This paper deals conceptually with some macroeconomic aspects of widespread substance abuse with special reference to narcotic drugs.
Levy, Amnon, Neri, Frank
core  

Integrin α8‐Mediated Pericyte Morphogenesis Controls Blood‐Brain Barrier Integrity

open access: yesAdvanced Science, EarlyView.
This study highlights that ITGA8 impacts pericyte morphology and function, both crucial for BBB integrity, via RhoA/ROCK signaling, thus influencing TGF‐β1 activation through cytoskeletal tension and ECM interactions. Notably, in post‐ischemic recovery models, ITGA8 deficiency exacerbates vascular dysfunction by impairing pericyte‐mediated BBB ...
Chang‐Xiong Gong   +16 more
wiley   +1 more source

Addiction Recovery Support: Connecting Primary Care Providers and Community Resources [PDF]

open access: yes, 2017
Addiction to drugs and alcohol is a pervasive problem throughout Vermont and the U.S., and only a fraction of those needing help receive it. The vast majority of admissions to substance abuse treatment programs do not come from healthcare providers, who ...
Meservey, Amber J
core   +1 more source

Human iPSC‐Derived Mononuclear Phagocytes Improve Cognition and Neural Health across Multiple Mouse Models of Aging and Alzheimer's Disease

open access: yesAdvanced Science, EarlyView.
Short‐term intravenous treatments with iPSC‐derived mononuclear phagocytes (iMPs) improve cognitive decline and neural health in two mouse models of aging and in the 5xFAD mouse model of Alzheimer's disease. iMPs reduce levels of serum amyloid proteins that increase in aging and improve the health of hippocampal microglia and mossy cells.
V. Alexandra Moser   +11 more
wiley   +1 more source

The Effectiveness of Cognitive-Behavioral-Based Stress Management Training on Anxiety in Female MS Patients

open access: yesIranian Rehabilitation Journal, 2015
Objectives: This present study aims to examine the effectiveness of cognitive-behavioral-based stress management training on anxiety in female MS patients. Methods: This study employed a semi-experimental research method with pre-test post-test, control
Shafigh Mehraban   +3 more
doaj  

Teen Substance Use and Abuse in the Growing Metro of Des Moines, Iowa [PDF]

open access: yes, 2017
uVoice, a youth philanthropy board comprised of twelve students from seven Des Moines-area high schools, spent 2016 identifying unmet needs of central Iowa youth, specifically issues related to substance abuse.Students wrote and released a "White Paper ...

core  

RELA Ablation Contributes to Progression of Hepatocellular Carcinoma with TP53R249S Mutation and is a Potential Therapeutic Target

open access: yesAdvanced Science, EarlyView.
Genome‐wide CRISPR/Cas9 based screening identified RELA as a key tumor suppressor in TP53R249S‐mutant HCC. Its loss promotes tumorigenesis and metastasis via DVL1‐mediated Wnt/β‐catenin activation, while its agonist betulinic acid suppresses tumor progression.
Zhiping Wu   +17 more
wiley   +1 more source

The role of attributions in abstinence, lapse, and relapse following substance abuse treatment [PDF]

open access: green, 1994
Maureen A. Walton   +2 more
openalex   +1 more source

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