Results 1 to 10 of about 21,551,551 (367)

Substance P participates in periodontitis by upregulating HIF-1α and RANKL/OPG ratio [PDF]

BMC Oral Health, 2020
Both substance P and hypoxia-inducible factor 1 alpha (HIF-1α) are involved in inflammation and angiogenesis. However, the relationship between substance P and HIF-1α in rat periodontitis is still unknown.
Kaixian Yan, Qin Lin, Kailiang Tang, Shuang Liu, Yi Du, Xijiao Yu, Shu Li   +6 more
openalex   +2 more sources

A paradox from a neurotransmitter: the opposite effects of substance P and its physiological fragments SP (1-7) and SP (9-11) on the proliferation of human breast cancer cells and the migration capabilities of HUVEC cells [PDF]

World Cancer Research Journal, 2022
OBJECTIVE: Substance P (SP) is a neurotransmitter peptide, and it is known to play a major role in neurogenic inflammation, inducing local inflammatory responses, cancer, and angiogenesis.
O. Koçak, E. Şimşek
doaj   +2 more sources

TRPV1 activity and substance P release are required for corneal cold nociception [PDF]

Nature Communications, 2019
As a protective mechanism, the cornea is sensitive to noxious stimuli. Here, we show that in mice, a high proportion of corneal TRPM8+ cold-sensing fibers express the heat-sensitive TRPV1 channel.
Fengxian Li, Weishan Yang, Haowu Jiang, Changxiong J. Guo, A. Huang, Hongzhen Hu, Qin Liu   +6 more
semanticscholar   +3 more sources

Proteolysis controls endogenous substance P levels. [PDF]

PLoS ONE, 2013
Substance P (SP) is a prototypical neuropeptide with roles in pain and inflammation. Numerous mechanisms regulate endogenous SP levels, including the differential expression of SP mRNA and the controlled secretion of SP from neurons. Proteolysis has long
Andrew J Mitchell, Anna Mari Lone, Arthur D Tinoco, Alan Saghatelian   +3 more
doaj   +6 more sources

Substance P causes seizures in neurocysticercosis. [PDF]

PLoS Pathogens, 2012
Neurocysticercosis (NCC), a helminth infection of the brain, is a major cause of seizures. The mediators responsible for seizures in NCC are unknown, and their management remains controversial.
Prema Robinson, Armandina Garza, Joel Weinstock, Jose A Serpa, Jerry Clay Goodman, Kristian T Eckols, Bahrom Firozgary, David J Tweardy   +7 more
doaj   +2 more sources

Expression of substance P and neurokinin-1 receptor in nasopharyngeal carcinoma and their clinical significance

Di-san junyi daxue xuebao, 2020
Objective To investigate the expression of substance P (SP) and its receptor, neurokinin-1 receptor (NK-1R), in nasopharyngeal carcinoma (NPC) tissues and their correlation with the clinicopathological parameters of the patients.
ZHANG Yu, YANG Yucheng, YANG Kun, FENG Dandan, HUANG Jiangju   +4 more
doaj   +2 more sources

Substance P [PDF]

Definitions, 2020
openaire   +2 more sources

Neuropeptide substance P and the immune response

Cellular and Molecular Life Sciences, 2016
Alireza Mashaghi, Anna Marmalidou, Mohsen Tehrani, Peter M. Grace, Charalabos Pothoulakis, Reza Dana   +5 more
openalex   +2 more sources

Neuronal substance P drives metastasis through an extracellular RNA-TLR7 axis. [PDF]

Nature
Padmanaban V, Keller I, Seltzer ES, Ostendorf BN, Kerner Z, Tavazoie SF.   +5 more
europepmc   +2 more sources

The impact of psychological assistance in Italian Primary Care: data collected from 2016 to 2018 in the district of Bologna

Mediterranean Journal of Clinical Psychology, 2023
It is common for a general practitioner to meet patients who suffer from mental disorders such as depression or anxiety in the context of Primary Care (Alexander et al., 2008; Anthony et al., 2010; Consensus ISS, 2022; Regier et al. 1978, 1993; Goldberg
Bianca Vivit, Luigi Rocco Chiri, Emanuele Ciotti, Chiara Patierno, Gabriella Gallo, Marco Chiappelli, Angelo Fioritti, Domenico Berardi, Marco Menchetti   +8 more
doaj   +1 more source