Results 1 to 10 of about 2,081,542 (179)
Proteolysis controls endogenous substance P levels. [PDF]
PLoS ONE, 2013 Substance P (SP) is a prototypical neuropeptide with roles in pain and inflammation. Numerous mechanisms regulate endogenous SP levels, including the differential expression of SP mRNA and the controlled secretion of SP from neurons. Proteolysis has long
Andrew J Mitchell +3 more
doaj +6 more sources
Mediterranean Journal of Clinical Psychology, 2023 It is common for a general practitioner to meet patients who suffer from mental disorders such as depression or anxiety in the context of Primary Care (Alexander et al., 2008; Anthony et al., 2010; Consensus ISS, 2022; Regier et al. 1978, 1993; Goldberg
Bianca Vivit +8 more
doaj +1 more source
A paradox from a neurotransmitter: the opposite effects of substance P and its physiological fragments SP (1-7) and SP (9-11) on the proliferation of human breast cancer cells and the migration capabilities of HUVEC cells [PDF]
World Cancer Research Journal, 2022 OBJECTIVE: Substance P (SP) is a neurotransmitter peptide, and it is known to play a major role in neurogenic inflammation, inducing local inflammatory responses, cancer, and angiogenesis.
O. Koçak, E. Şimşek
doaj +1 more source
Evaluation of Serum Substance P Level and Tissue Distribution of NK-1 Receptor in Papillary Thyroid Cancer [PDF]
Middle East Journal of Cancer, 2021 Background: Papillary thyroid carcinoma (PTC) is the most prevalent malignancy of the endocrine system. This study was aimed at evaluating the serum substance P (SP) levels, the tissue distribution of Neurokinin-1 receptors (NK1-R), and their possible ...
Mahdi Asadi +5 more
doaj +1 more source
Open Chemistry, 2020 Clopidogrel (CLOP) is widely used worldwide for cardiovascular complications. CLOP is highly metabolized in the liver to its active metabolite by cytochrome P450 enzymes.
Alhazmi Hassan A. +5 more
doaj +1 more source
Journal of Investigative Dermatology, 1981 Substance P is present in numerous organs (salivary glands, trachea, pancreas, kidneys, bladder and prostate) and in various parts of the central and peripheral nervous system, notably substantia nigra, hypothalamus, pineal body and dorsal horn of the spinal cord.
Bernstein, Joel E., Hamill, J. Robert
openaire +4 more sources
The Implication of Substance P in the Development of Tendinopathy: A Case Control Study. [PDF]
, 2017 It was reported that substance P had beneficial effects in the healing of acute tendon injury. However, the relationship between substance P and degenerative tendinopathy development remains unclear. The purpose of this study was to determine the role of
Ahn, Heejung +13 more
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Gene expression changes of angiogenesis factors during basal skin cancer laser destruction [PDF]
Vestnik Dermatologii i Venerologii, 2023 Background. Basal cell carcinoma is the most widespread malignant skin neoplasm. Angiogenesis is critical for the growth and metastasis of malignant tumors. Aims.
Rifat R. Saytburkhanov +6 more
doaj +1 more source
Pifu-xingbing zhenliaoxue zazhi, 2022 Objective To investigate association between CCL17, CCL22 and substance P (SP) and pruritus in patients with bullous pemphigoid (BP) pruritus. Methods Clinical data of 30 patients and 10 healthy controls were collected.
Manman ZHANG, Xiaohong LI, Yan LIU
doaj +1 more source
The Role of Pregnancy Concerns in the Relationship between Substance Use and Unprotected Sex among Adolescents [PDF]
, 2019 BACKGROUND: Substance use and unprotected sex are prevalent among adolescents. The link between substance use and unprotected sex is well-established.
Aalsma, Matthew C. +2 more
core +1 more source