Proteolysis controls endogenous substance P levels. [PDF]
PLoS ONE, 2013 Substance P (SP) is a prototypical neuropeptide with roles in pain and inflammation. Numerous mechanisms regulate endogenous SP levels, including the differential expression of SP mRNA and the controlled secretion of SP from neurons. Proteolysis has long
Andrew J Mitchell +3 more
doaj +6 more sources
The Implication of Substance P in the Development of Tendinopathy: A Case Control Study. [PDF]
, 2017 It was reported that substance P had beneficial effects in the healing of acute tendon injury. However, the relationship between substance P and degenerative tendinopathy development remains unclear. The purpose of this study was to determine the role of
Ahn, Heejung +13 more
core +1 more source
The Role of Pregnancy Concerns in the Relationship between Substance Use and Unprotected Sex among Adolescents [PDF]
, 2019 BACKGROUND: Substance use and unprotected sex are prevalent among adolescents. The link between substance use and unprotected sex is well-established.
Aalsma, Matthew C. +2 more
core +1 more source
Substance Use Among Lesbian, Gay, and Bisexual Clients Entering Substance Abuse Treatment: Comparisons to Heterosexual Clients [PDF]
, 2015 Objective: This study evaluated whether sexual orientation-specific differences in substance use behaviors exist among adults entering substance abuse treatment. Method: Admissions records (July 2007–December 2009) were examined for treatment programs in
Flentje, Annesa +2 more
core +3 more sources
Substance P regulates puberty onset and fertility in the female mouse [PDF]
, 2015 Puberty is a tightly regulated process that leads to reproductive capacity. Kiss1 neurons are crucial in this process by stimulating GnRH, yet how Kiss1 neurons are regulated remains unknown. Substance P (SP), an important neuropeptide in pain perception,
Carroll, R.S. +7 more
core +1 more source
Combined Unilateral Blockade of Cholinergic, Peptidergic, And Serotonergic Receptors in The Ventral Respiratory Column Does Not Affect Breathing in Awake Or Sleeping Goats [PDF]
, 2015 Previous work in intact awake and sleeping goats has found that unilateral blockade of excitatory inputs in the ventral respiratory column (VRC) elicits changes in the concentrations of multiple neurochemicals, including serotonin (5-HT), substance P ...
Forster, Hubert +7 more
core +2 more sources
The effect of acute caffeine ingestion on upper and lower body anaerobic exercise performance [PDF]
, 2019 The current study examined the effect of acute caffeine ingestion on mean and peak power production, fatigue index and rating of perceived exertion (RPE) during upper body and lower body Wingate anaerobic test (WANT) performance.
Andre T. +9 more
core +1 more source
Pathogenic role of the SP/ NK1R system in GBM cells through inhibiting the thioredoxin system [PDF]
Iranian Journal of Basic Medical Sciences, 2021 Objective(s): Glioblastoma multiforme (GBM), a highly aggressive Grade IV brain tumor, is a significant public health issue due to its poor prognosis and incurability.
Fatemeh Ghahremani +5 more
doaj +1 more source
The concept of waste and waste management [PDF]
, 2016 <p>Several studies and researches have been conducted on the sources and characteristics of wastes as well as the possible adverse effect of inappropriate handling and best international practices.
Amasuomo, Ebikapade, Baird, Jim
core +1 more source
Substance P and neprilysin in chronic pancreatitis [PDF]
, 2012 Background/Aims: We aimed to analyze substance P (SP) and neprilysin (NEP), the membrane metallopeptidase that degrades SP, in chronic pancreatitis (CP).
Bassi, Claudio +8 more
core +3 more sources