Results 91 to 100 of about 22,248,138 (428)
Thermodynamics of Substances with Negative Thermal Expansion Coefficient [PDF]
arXiv, 2000 The 1st law of thermodynamics for heat exchange is dQ=dU+PdV. According to K. Martinas etc., J. Non-Equil. Thermod. 23 (4), 351-375 (1988), for substances with negative thermal expansion coefficient, P in this law is negative. In the present paper it has been shown that P for such substances is positive but the sign before P must be minus not plus: dQ ...
arxiv
FEBS Letters, EarlyView.Heart failure with preserved ejection fraction (HFpEF) accounts for half of the heart failure cases. It is characterised by microvascular dysfunction, associated with reduced pericyte coverage and diminished STAT3 expression in pericytes. Loss of STAT3 impairs pericyte adhesion, promotes senescence, and activates a pro‐fibrotic gene program.
Leah Rebecca Vanicek +15 more
wiley +1 more source
Submicroscopic structure of the egg shell of helminth II. A study on Trichuris vulpis [PDF]
, 1960 Electron microscopic structures of the egg shell and the plug of the ova of Trichuris vulpis have been demonstrated. The shell is of one thick membrane of about 4 microns in thickness and consisted of several opaque and less opaque layers arranged in ...
Inatomi, Seiiti
core +1 more source
Kenneth Geddes Wilson (1936-2013) [PDF]
arXiv, 2014 Wilson was a physicist who changed both the substance and style of theoretical science.
arxiv
Ion channel function of polycystin‐2/polycystin‐1 heteromer revealed by structure‐guided mutagenesis
FEBS Letters, EarlyView.Mutations in polycystin‐1 (PC1) or polycystin‐2 (PC2) cause autosomal‐dominant polycystic kidney disease (ADPKD). We generated a novel gain‐of‐function PC2/PC1 heteromeric ion channel by mutating pore‐blocking residues. Moreover, we demonstrated that PC2 will preferentially assemble with PC1 to form heteromeric complexes when PC1 is co‐expressed ...
Tobias Staudner +7 more
wiley +1 more source
Autophagy in cancer and protein conformational disorders
FEBS Letters, EarlyView.Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley +1 more source
FEBS Letters, EarlyView.The protonated form of butyrate, as well as other short‐chain fatty acids (SCFAs), is membrane permeable. In acidic extracellular environments, this can lead to intracellular accumulation of SCFAs and cytosolic acidification. This phenomenon will be particularly relevant in acidic environments such as the large intestine or tumor microenvironments ...
Muwei Jiang +2 more
wiley +1 more source
A stepwise emergence of evolution in the RNA world
FEBS Letters, EarlyView.How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley +1 more source
Substance P-expressing excitatory interneurons in the mouse superficial dorsal horn provide a propriospinal input to the lateral spinal nucleus [PDF]
, 2018 The superficial dorsal horn (laminae I and II) of the spinal cord contains numerous excitatory and inhibitory interneurons, and recent studies have shown that each of these groups can be divided into several neurochemically distinct populations. Although
Bell, Andrew M. +4 more
core +1 more source
Substance P in Long-Lasting Asthma: Immunoinflammatory pathways [PDF]
, 2006 Background: Substance P (SP) was described at the beginning of the 20th Century, and its biological action was recognized to have implications in neurogenic inflammation and constriction of smooth muscles.
Alves, V +5 more
core +4 more sources