The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld+7 more
wiley +1 more source
Ginzburg-Landau Theory for Impure Superfluid 3He [PDF]
Liquid 3He at low temperatures is an ideal substance to study because of its natural purity. The superfluid state, which appears at temperatures below 3 mK, has many unusual and exciting properties. These have extensively been studied experimentally, and the results are in many cases well understood theoretically using quasiclassical approximation.
arxiv
Ch.-H. LEES et G.-D. CHORLTON. — On a simple apparatus for determining the thermal conductivities of cements and other subtances used in the arts (Appareil simple pour déterminer les conductibilités thermiques de ciments et d'autres substances employées dans les arts); Phil. Mag., 5e série, t. XLI, p. 495 ; 1896 [PDF]
E. Bouty
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This study simultaneously investigated circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients. The elevated expression of JUNB and CXCR4 in CTCs was a poor prognostic factor for SCLC patients, whereas exosomal overexpression of these biomarkers revealed a high discrimination ability of patients from healthy individuals,
Dimitrios Papakonstantinou+13 more
wiley +1 more source
W.-J. HAMMER. — Radium and other radioactive substances with a consideration of phosphorescent and fluorescent substances. The properties and applications of selénium and the treatment of disease by the ultraviolet light (Radium et autres substances radioactives, substances phosphorescentes et fluorescentes. Les propriétés et applications du sélénium et le traitement du lupus par la lumière ultraviolette). — P. 64 [PDF]
G. Sagnac
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MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin+14 more
wiley +1 more source
Psychoemotional and humoral changes in patients with combined reflux disorders
Aim. To investigate disorders of psychoemotional functions, humoral regulation (substance P) and duodenal motility (DM) in patients with combined refluxes for their differential correction. Material and methods.
Vadim Adil'evich Akhmedov+3 more
doaj
Effects of Neuropeptides on Dendritic Cells in the Pathogenesis of Psoriasis
Jingya Zhang,1 Siqi Zhao,1 Xinzhu Xing,1 Lin Shang,1 Jiali Cao,1 Yanling He1,2 1Department of Dermatology, Beijing Chaoyang Hospital, Capital Medical University, Beijing, People’s Republic of China; 2National Clinical Research Center for Skin and Immune ...
Zhang J+5 more
doaj
OLIVER-J. LODGE. — On a method of measuring the absolute thermal conductivity of crystals and other rare substances (Méthode pour mesurer la conductibilité calorifique absolue des cristaux ou d'autres substances rares); Philosophical Magazine, 5e série, t. V, p. 110; 1878 [PDF]
E. Bouty
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Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane+16 more
wiley +1 more source