Results 151 to 160 of about 22,248,138 (428)

Circulating tumor DNA (ctDNA) trajectories predict survival in trifluridine/tipiracil‐treated metastatic colorectal cancer patients

open access: yesMolecular Oncology, EarlyView.
The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld   +7 more
wiley   +1 more source

Ginzburg-Landau Theory for Impure Superfluid 3He [PDF]

open access: yesin "Quasiclassical methods in superconductivity and superfluidity, Verditz 96", eds. D. Rainer and J.A. Sauls (1998) p. 53, 1998
Liquid 3He at low temperatures is an ideal substance to study because of its natural purity. The superfluid state, which appears at temperatures below 3 mK, has many unusual and exciting properties. These have extensively been studied experimentally, and the results are in many cases well understood theoretically using quasiclassical approximation.
arxiv  

Integrative analysis of circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients: a comprehensive approach

open access: yesMolecular Oncology, EarlyView.
This study simultaneously investigated circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients. The elevated expression of JUNB and CXCR4 in CTCs was a poor prognostic factor for SCLC patients, whereas exosomal overexpression of these biomarkers revealed a high discrimination ability of patients from healthy individuals,
Dimitrios Papakonstantinou   +13 more
wiley   +1 more source

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

open access: yesMolecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin   +14 more
wiley   +1 more source

Psychoemotional and humoral changes in patients with combined reflux disorders

open access: yesТерапевтический архив, 2009
Aim. To investigate disorders of psychoemotional functions, humoral regulation (substance P) and duodenal motility (DM) in patients with combined refluxes for their differential correction. Material and methods.
Vadim Adil'evich Akhmedov   +3 more
doaj  

Effects of Neuropeptides on Dendritic Cells in the Pathogenesis of Psoriasis

open access: yesJournal of Inflammation Research, 2023
Jingya Zhang,1 Siqi Zhao,1 Xinzhu Xing,1 Lin Shang,1 Jiali Cao,1 Yanling He1,2 1Department of Dermatology, Beijing Chaoyang Hospital, Capital Medical University, Beijing, People’s Republic of China; 2National Clinical Research Center for Skin and Immune ...
Zhang J   +5 more
doaj  

Response to neoadjuvant chemotherapy in early breast cancers is associated with epithelial–mesenchymal transition and tumor‐infiltrating lymphocytes

open access: yesMolecular Oncology, EarlyView.
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane   +16 more
wiley   +1 more source

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