Results 191 to 200 of about 628,291 (259)

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

FEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar, Francesco Michelangeli, Farhat Latif Khanim, Christopher Martin Bunce, William Eustace Basil Johnson   +4 more
wiley   +1 more source

Substance P release from rat dura mater is inversely correlated with CGRP release- experiments using glycerol trinitrate and anti-CGRP antibodies. [PDF]

J Headache Pain
Dux M, Messlinger K.
europepmc   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source

Serum MRGPRX2 and substance P levels are biomarkers of disease activity rather than an antihistamine response in chronic spontaneous urticaria. [PDF]

Sci Rep
Cuc NTK, Minh VN, Lan PT, My LH, Doanh LH.   +4 more
europepmc   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Temperature-Dependent Trimethylamine <i>N</i>-Oxide Induced the Formation of Substance P Dimers. [PDF]

J Phys Chem B
Lantz C, Xi Z, Rider RL, Walker TE, Hebert M, Russell DH.   +5 more
europepmc   +1 more source

Comparison between Substance P and Calcitonin Gene-Related Peptide and Their Receptors in Colorectal Adenocarcinoma. [PDF]

J Clin Med
Șerban RE, Boldeanu MV, Florescu DN, Ionescu M, Șerbănescu MS, Boldeanu L, Florescu MM, Stepan MD, Obleagă VC, Constantin C, Popescu DM, Streba CT, Vere CC.   +12 more
europepmc   +1 more source

Substance P regulates memory Th17 cell generation and maintenance in chronic dry eye disease. [PDF]

J Leukoc Biol
Wang S, Naderi A, Kahale F, Ortiz G, Forouzanfar K, Chen Y, Dana R.   +6 more
europepmc   +1 more source

Evaluating the efficacy of neurokinin-1 (substance P) receptor antagonist CP-99994 on facial grimacing and allodynia in mice postsurgery: a comparative study with known analgesics. [PDF]

Pain
McCoy ES, Ryan DF, Park SK, Zylka MJ.
europepmc   +1 more source

Exploring the relationship between plasma substance P and glottal incompetence in the elderly. [PDF]

Heliyon
Tsunoda K, Ishii T, Kuroda H, Nakatani H, Tateda M, Masuda S, Takiguchi T, Tanaka F, Misawa H, Senarita M, Takazawa M, Itoh K, Baer T.   +12 more
europepmc   +1 more source