Results 191 to 200 of about 647,395 (219)

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

Comparative Evaluation of Herbal and Conventional Endodontic Irrigants on Postoperative Pain and Substance P Levels in Patients With Symptomatic Irreversible Pulpitis and Apical Periodontitis. [PDF]

Cureus
Hassan L, Taneja S, Bhalla V, Katyal S.
europepmc   +1 more source

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

Molecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David, Arthur Karaulic, Audrey Bennetot, Clémence Fournier, Quentin Odet, Arthur Gouraud, Isabelle Bourget, Cédric Gaggioli, Sandy Giuliano, Frédéric Luciano, Olivier Léger, Zaki Sellam, Gilles Pagès   +12 more
wiley   +1 more source

Pain persists in mice lacking both Substance P and CGRPα signaling. [PDF]

Elife
MacDonald DI, Jayabalan M, Seaman JT, Balaji R, Nickolls AR, Chesler AT.   +5 more
europepmc   +1 more source

The Double-Edged Effects of Substance P in the Pathology of Alzheimer's Disease. [PDF]

Aging Dis
Lin Z, Yu S, Yang Y, Mu H, Hu Y, Yu W, Lü Y.   +6 more
europepmc   +1 more source

Production and characterization of rNGFSP: a recombinant fusion immunogen eliciting dual anti-NGF and anti-Substance P therapeutic antibodies for Degenerative Joint Disease. [PDF]

Biotechnol Rep (Amst)
Varela V, Costa M, Maciel C, Barbeito J, Barrera EE, Gutierre E, Correa A, Elgue M, Carrasco S, Larrosa MD, Pereira M, Correa J, Crosignani N, Beckman JS, Barbeito L, Trias E.   +15 more
europepmc   +1 more source

Mediation Effect of CSF Substance P on the Association Between Smoking and Sleep. [PDF]

Brain Behav
Zhang X, Chen L, Wu Y, Chen YH, Luo X, Xu Z, Hu W, Kang Y, Chen L, Liu Y, Wang F, Liu D.   +11 more
europepmc   +1 more source

Substance P Augments Chemokine Production by Staphylococcus aureus Infected Murine Osteoclasts. [PDF]

Inflammation
Sipprell SE, Krueger QA, Mills EL, Marriott I, Johnson MB.   +4 more
europepmc   +1 more source

Evaluation of a near infrared spectroscopy based method for the estimation of substance P in saliva of patients with COPD. [PDF]

Sci Rep
Jiménez-Ruiz JA, Reinoso-Arija R, Marin-Hinojosa C, Fernandez-Boza A, Muñoz-Sanchez B, Carrera-Cueva C, Caballero C, Quintana-Gallego E, Otero-Candelera R, Lopez-Campos JL.   +9 more
europepmc   +1 more source

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Evolution of Plant Protection Active Substances in Europe: The Disappearance of Chemicals in Favour of Biocontrol Agents

Environmental Science and Pollution Research, 2023
Patrice A Marchand
exaly