Results 211 to 220 of about 22,248,138 (428)

The anticancer effect of the HDAC inhibitor belinostat is enhanced by inhibitors of Bcl‐xL or Mcl‐1 in ovarian cancer

Molecular Oncology, EarlyView.
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine, Sterenn Guillemot, Louis‐Bastien Weiswald, Romane Florent, Edwige Abeilard, Florence Giffard, Emilie Brotin, Mélanie Briand, Enora Dolivet, Laurent Poulain, Marie Villedieu   +10 more
wiley   +1 more source

Ferrocenyl-Substituted Curcumin Derivatives as Potential SHP‑2 Inhibitors for Anticolorectal Cancer: Design, Synthesis and In Vitro Evaluation

ACS Omega
Xing-Ze Zhang, Gen Li, Gao-Yong Hu, Chen-Lin Wang, Yu-Qiu Fang, Yuye Li, Xue-Jie Qi, Lili Duan   +7 more
doaj   +1 more source

Reactive Oxygen Species Induced Upregulation of TRPV1 in Dorsal Root Ganglia Results in Low Back Pain in Rats

Journal of Inflammation Research
Xinyong Chen,1,2,* Zhe Chen,3,* Gongchang Ma,2 Jianjun Sha,2 Shan Zhao,2 Zuoqing Liu,2 Nong Chen,2 Huilin Yang1 1Department of Orthopedics, The First Affiliated Hospital of Soochow University, Suzhou, 215000, People’s Republic of China ...
Chen X, Chen Z, Ma G, Sha J, Zhao S, Liu Z, Chen N, Yang H   +7 more
doaj  

The Role of <i>Substance P</i> in Corneal Homeostasis. [PDF]

Biomolecules
Irmina JM, Bartosz M, Dorota WP, Adrian S.   +3 more
europepmc   +1 more source

Retracted: Elevated Substance P Is a Risk Factor for Postoperative Delirium in Patients with Hip Fracture. [PDF]

Biomed Res Int, 2023
International BR.
europepmc   +1 more source

STUDIES ON ANTIMICROBIAL SUBSTANCE B 44 P (STREPTOVARICIN) PRODUCED BY A STRAIN OF ACTINOMYCETES. I

, 1968
Hisaji Yamazaki
openalex   +2 more sources

Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer

Molecular Oncology, EarlyView.
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte, Osheen Sharma, Laura Leuenberger, Emelie Wallin, Josefin Fernebro, Päivi Östling, Rebecka Bergström, Johan Lindberg, Ulrika Joneborg, Olli Kallioniemi, Brinton Seashore‐Ludlow   +10 more
wiley   +1 more source

Pain persists in mice lacking both Substance P and CGRPα signaling. [PDF]

Elife
MacDonald DI, Jayabalan M, Seaman JT, Balaji R, Nickolls AR, Chesler AT.   +5 more
europepmc   +1 more source

Substance P promotes epidural fibrosis via induction of type 2 macrophages. [PDF]

Neural Regen Res, 2023
Hua F, Wang HR, Bai YF, Sun JP, Wang WS, Xu Y, Zhang MS, Liu J.   +7 more
europepmc   +1 more source

Mast cell activation — a receptor‐independent mode of substance P action? [PDF]

, 1987
H Repke, Michael Bienert
openalex   +1 more source