Results 231 to 240 of about 2,039,151 (340)

The ACCEPTance of automation: refining circulating tumor cells enumeration for improved metastatic colorectal cancer prognosis

Molecular Oncology, EarlyView.
This study highlights the potential of automated enumeration using the ACCEPT software to refine circulating tumor cell (CTC) detection in metastatic colorectal cancer (mCRC). The automated method demonstrates improved accuracy and reduced variability compared to the manual approach.
Michela De Meo, Marco Siringo, Alessandro Vici, Ann Zeuner, Orietta Gandini, Paola Gazzaniga, Chiara Nicolazzo   +6 more
wiley   +1 more source

The MRGPRX2-substance P pathway regulates mast cell migration. [PDF]

iScience
West PW, Chéret J, Bahri R, Kiss O, Wu Z, Macphee CH, Bulfone-Paus S.   +6 more
europepmc   +1 more source

Non‐cholinergic excitatory transmission in inferior mesenteric ganglia of the guinea‐pig: possible mediation by substance P.

, 1982
Nae J. Dun, Zhengxuan Jiang
openalex   +2 more sources

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Substance P receptor signaling contributes to host maladaptive responses during enteric bacterial infection. [PDF]

Proc Natl Acad Sci U S A
Cremin M, Ramirez VT, Sanchez K, Tay E, Murray K, Brust-Mascher I, Reardon C.   +6 more
europepmc   +1 more source

Studies on the Cardiovascular Effects Produced by the Spinal Action of Substance P in the Rat

, 1988
Réjean Couture, Harout Hasséssian, Alka Gupta   +2 more
openalex   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Serum MRGPRX2 and substance P levels are biomarkers of disease activity rather than an antihistamine response in chronic spontaneous urticaria. [PDF]

Sci Rep
Cuc NTK, Minh VN, Lan PT, My LH, Doanh LH.   +4 more
europepmc   +1 more source

TRPV1 activity and substance P release are required for corneal cold nociception [PDF]

, 2019
Guo, Changxiong, Hu, Hongzhen, Huang, Andrew J.W., Jiang, Haowu, Li, Fengxian, Liu, Qin, Yang, Weishan   +6 more
core   +1 more source

Substance P-containing nerve fibers are numerous in human but not in feline intestinal mucosa

, 1983
Ernst Brodin, K. Sjölund, R. Håkanson, F. Sundler   +3 more
openalex   +1 more source