Results 241 to 250 of about 21,551,551 (367)

Systemic role of orexin A, substance P, bradykinin, and DABK in severe COVID-19 and 2.5-yr follow-ups: an observational study. [PDF]

BJA Open
Heinicke U, Talbot SR, Thanasis F, Adam EH, von Knethen A, Steinbicker AU, Zinn S, Zacharowski K, Flinspach AN.   +8 more
europepmc   +1 more source

Release of substance P-like material from peripheral nerve terminals of sensory neurones into the perfusate of rat hind paw by heating

, 1986
Norifumi Yonehara, Tooru Shibutani, Reizo Inoki   +2 more
openalex   +1 more source

TRPA1 and substance P mediate colitis in mice.

Gastroenterology, 2011
M. Engel, A. Leffler, F. Niedermirtl, A. Babes, K. Zimmermann, M. Filipović, I. Izydorczyk, M. Eberhardt, T. Kichko, Sonja M. Mueller-Tribbensee, M. Khalil, Norbert Siklósi, C. Nau, I. Ivanović‐Burmazović, W. Neuhuber, C. Becker, M. Neurath, P. Reeh   +17 more
semanticscholar   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Revisiting substance P in migraine: a methodological approach inspired by anti-CGRP and anti-PACAP success. [PDF]

J Headache Pain
Pellesi L, Edvinsson L.
europepmc   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

The role of pallidal substance P and neurokinin receptors in the consolidation of spatial memory of rats. [PDF]

Int J Neuropsychopharmacol
Kertes E, Péczely L, Ollmann T, László K, Berta B, Kállai V, Zagorácz O, Kovács A, Szabó Á, Karádi Z, Lénárd L.   +10 more
europepmc   +1 more source

Substance P, the NK-1 Receptor and NK-1 Receptor Antagonists in Cancer Treatment [PDF]

, 2014

openalex   +1 more source

Substance P induces adverse myocardial remodelling via a mechanism involving cardiac mast cells.

Cardiovascular Research, 2011
Giselle C. Meléndez, Jianping Li, Brittany A. Law, J. S. Janicki, S. Supowit, S. Levick   +5 more
semanticscholar   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source