Results 81 to 90 of about 2,039,151 (340)
A working model for cytoplasmic assembly of H/ACA snoRNPs
FEBS Letters, EarlyView.Dyskerin is the component of nuclear H/ACA ribonucleoproteins (RNPs) endowed with pseudouridine synthase catalytic activity. Two isoforms of human dyskerin have been characterized: the abundant Iso1, mainly nuclear, and the shorter Iso3, mainly cytoplasmic but occasionally imported into nuclei.
Alberto Angrisani, Maria Furia
wiley +1 more source
International Journal of Nanomedicine, 2022 Yanying Li,1,2 Jingliang Wu,2 Qiao Lu,1 Xuemin Liu,2 Jiaxuan Wen,3 Xiaohui Qi,1 Jianhao Liu,4 Bo Lian,1 Bo Zhang,4 Hengyi Sun,1 Guixiang Tian1 1School of Life Science and Technology, Weifang Medical University, Weifang, 261053, People’s Republic of China;
Li Y +10 more
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Combined Unilateral Blockade of Cholinergic, Peptidergic, And Serotonergic Receptors in The Ventral Respiratory Column Does Not Affect Breathing in Awake Or Sleeping Goats [PDF]
, 2015 Previous work in intact awake and sleeping goats has found that unilateral blockade of excitatory inputs in the ventral respiratory column (VRC) elicits changes in the concentrations of multiple neurochemicals, including serotonin (5-HT), substance P ...
Forster, Hubert +7 more
core +2 more sources
FEBS Letters, EarlyView.Antimicrobial resistance (AMR) is of huge importance, resulting in over 1 million deaths each year. Here, we describe how a new drug, enmetazobactam, designed to help fight resistant bacterial diseases, inhibits a key enzyme (GES‐1) responsible for AMR. Our data show it is a more potent inhibitor than the related tazobactam, with high‐level computation
Michael Beer +10 more
wiley +1 more source
Phase-conjugate reflection by degenerate four-wave mixing in a nematic liquid crystal in the isotropic phase [PDF]
, 1980 We report the generation of conjugate wave fronts by degenerate four-wave mixing in the isotropic phase of the nematic substance p-methoxy-benzylidene p-n-butylaniline. The temporal and spatial properties of the conjugate wave fronts are verified.
AuYeung, J., Fekete, D., Yariv, A.
core +1 more source
FEBS Letters, EarlyView.Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican +7 more
wiley +1 more source
Constructing a Theory of Educational Administration [PDF]
, 2018 The development of administrative theory has long been a quest for scholars in the field of educational administration. The beginnings of the development of a theory of educational administration began with Griffiths‘ (1959) now classic Administrative ...
Beach, Don M.
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Serotoninergic, peptidergic and GABAergic innervation of the ventrolateral and dorsolateral motor nuclei in the cat S1/S2 segments: An immunofluorescence study [PDF]
, 1994 Indirect single- and double-staining immunofluorescence techniques were used to study the serotoninergic, peptidergic and GABAergic innervation of the ventrolateral (Onuf's nucleus) and dorsolateral (innervating intrinsic foot sole muscles) nuclei ...
Arvidsson, U. (U.) +5 more
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FEBS Letters, EarlyView.Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona +4 more
wiley +1 more source
Substance P-immunoreactive neurons in hamster retinas [PDF]
, 1999 Light-microscopic immunocytochemistry was utilized to localize the different populations of substance P-immunoreactive (SP-IR) neurons in the hamster retina. Based on observation of 2505 SP-IR neurons in transverse sections, 34% were amacrine cells whose
Cheuk, W, Li, HB, So, KF
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