Results 91 to 100 of about 676,730 (305)
Endocrine Regulations, 2019 Objective. The aim of the present study was to demonstrate the spatial relationship between the c-Fos immunoreactive cells elicited by an acute treatment with neuroleptics including amisulpride (AMI), olanzapine (OLA), quetiapine (QUE), and aripiprazole (
Kiss Alexander, Osacka Jana
doaj +1 more source
Stability and Change in Substance Use Among Swedish Adolescents: A Latent Transition Analysis
, 2023 Background: Research is needed on how substance use patterns develop over time in the general adolescent population. This knowledge is crucial in calibrating prevention and other interventions.
Nicklas Dennermalm +5 more
core +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Relationship of Substance P with the Degree of Atopic Dermatitis Severity
Clinical, Cosmetic and Investigational Dermatology, 2021 Deryne Anggia Paramita, Khairina Nasution, Nova Zairina Lubis Department of Dermatology and Venereology, Faculty of Medicine, Universitas of Sumatera Utara, Sumatera Utara, 20155, IndonesiaCorrespondence: Deryne Anggia Paramita Email deryne.anggia@usu.ac.
Paramita DA, Nasution K, Lubis NZ
doaj
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
The association betweeen psychopathology and substance use in young people
, 2011 Includes abstract.Includes bibliographical references.The co-occurrence of problematic substance use and non-substance use psychopathology is very common in psychiatry, and is generally referred to as comorbidity.
Saban, Amina
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FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Plasma concentration of norepinephrine, β-endorphin, and substance P in lame dairy cows
Journal of Veterinary Research, 2018 Lameness is a painful and debilitating condition that affects dairy cows worldwide. The aim of this study was to determine the plasma concentration of norepinephrine, β-endorphin, and substance P in dairy cows with lameness and different mobility scores (
Rodriguez Alfredo Rosamel +4 more
doaj +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Depression and Substance Abuse: A Rationalization of a Vicious Circle [PDF]
While a mind-altering-substance consumption alleviates current level of depression, it facilitates future depression. Our analysis incorporates this trade off and shows that the stationary state of a consistently overly ambitious sophisticated substance ...
Faria, João Ricardo, Levy, Amnon
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