Results 41 to 50 of about 1,878,278 (369)

Leveraging current insights on IL‐10‐producing dendritic cells for developing effective immunotherapeutic approaches

FEBS Letters, EarlyView.
In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali, Gloria Giacomello, Michela Vuono, Silvia Gregori   +3 more
wiley   +1 more source

Substance use disorder and posttraumatic stress disorder symptomology on behavioral outcomes among juvenile justice youth [PDF]

, 2019
BACKGROUND AND OBJECTIVES: Substance use behaviors have been identified as a risk factor that places juveniles at greater risk for engaging in delinquent behaviors and continual contact with the juvenile justice system.
Achenbach TM, Capell H, Hayes AF, Khantzian EJ, Miller GA, Miller GA, Sanders J, Teplin LA   +7 more
core   +1 more source

Overview of Substance Use Disorders

DeckerMed Transitional Year Weekly Curriculum™, 2017
Substance use disorders are a major source of morbidity and mortality, contributing to a significant proportion of deaths in the United States and worldwide each year. A substantial rise in deaths related to drug overdoses in recent decades has drawn increasing public attention to this issue.
Emily Morse, Timothy Ando, Alexander Thompson   +2 more
openaire   +1 more source

FoxO1 signaling in B cell malignancies and its therapeutic targeting

FEBS Letters, EarlyView.
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac, Petra Pavelkova, Laura Ondrisova, Marek Mraz   +3 more
wiley   +1 more source

Computational Support for Substance Use Disorder Prevention, Detection, Treatment, and Recovery [PDF]

arXiv, 2020
Substance Use Disorders (SUDs) involve the misuse of any or several of a wide array of substances, such as alcohol, opioids, marijuana, and methamphetamine. SUDs are characterized by an inability to decrease use despite severe social, economic, and health-related consequences to the individual.
arxiv  

Substance Use Disorder Treatment Confidentiality Boot Camp [PDF]

, 2017
[Excerpt]: INTRODUCTION: The Health Law and Policy Programs at UNH School of Law, Institute for Health Policy and Practice, and the NH Citizens Health Initiative have contracted with several of the New Hampshire Building Capacity for Transformation ...
Cameron, Stephanie, Doyle, Marcy, Hodder, Lucy C., Muñiz, Christina, Ryer, Jeanne, EdD   +4 more
core   +1 more source

Substance Use and Depression Symptomatology: Measurement Invariance of the Beck Depression Inventory (BDI-II) among Non-Users and Frequent-Users of Alcohol, Nicotine and Cannabis [PDF]

, 2016
Depression is a highly heterogeneous condition, and identifying how symptoms present in various groups may greatly increase our understanding of its etiology.
Moore, Ashlee A., Neale, Michael C., Silberg, Judy L., Verhulst, Brad   +3 more
core   +4 more sources

Medications for Substance Use Disorders [PDF]

Social Work in Public Health, 2013
In this article, the authors briefly review the pharmacotherapeutic agents that are currently available for the treatment of substance use disorders. Nicotine replacement therapies are most effective for tobacco cessation. Naltrexone, acamprosate, and disulfiram are effective for reducing alcohol use. The most effective pharmacotherapies for opiate use
Antoine Douaihy, Thomas M. Kelly, Carl R. Sullivan   +2 more
openaire   +3 more sources

Taurine promotes glucagon‐like peptide‐1 secretion in enteroendocrine L cells

FEBS Letters, EarlyView.
Taurine, a sulfur‐containing amino acid, is likely taken up by enteroendocrine L cells via the taurine transporter. This process increases the levels of cytosolic ATP. The increase in intracellular Ca2+ concentrations and glucagon‐like peptide‐1 secretion through membrane depolarization is caused by the closure of ATP‐sensitive potassium channels ...
Yuri Osuga, Kazuki Harada, Takuya Yamauchi, Tetsuya Kitaguchi, Masami Yokota Hirai, Mitsuharu Matsumoto, Takashi Tsuboi   +6 more
wiley   +1 more source

Does Gender Moderate the Relationship Between Chronic Pain and Substance Use Disorder? Insights From a National Canadian Population Survey

Frontiers in Psychiatry, 2022
BackgroundThough it has been shown that men have a higher lifetime prevalence of substance use disorder and a lower prevalence of chronic pain than women, there is little research to date focusing on gender differences in the relationship between chronic
Yingying Su, Yingying Su, Xiangfei Meng, Carl D'Arcy, Carl D'Arcy   +4 more
doaj   +1 more source