Results 91 to 100 of about 1,949,500 (369)

Does type and number of used substances affect the severity of illness in patients with substance use disorders?

The Egyptian Journal of Neurology, Psychiatry and Neurosurgery, 2021
Background Substance use disorders (SUD) are considered as serious mental illnesses, with variability of age of onset, duration of illness, and type of used substance among patients.
Maha Ali Hassan, Mohamed Ayman Abdelhameed, Mostafa Mahmoud Abd El-Naem, Mohamed Helmy Abdelhafeez   +3 more
doaj   +1 more source

Externalizing disorders and substance use: empirically derived subtypes in a population-based sample of adults. [PDF]

, 2014
PURPOSE: Attention-deficit/hyperactivity disorder (ADHD), conduct disorder (CD), and oppositional defiant disorder (ODD) are common externalizing disorders of childhood. The common effects of these disorders on substance abuse need further investigation.
Ajdacic-Gross, V., Castelao, E., Müller, M., Preisig, M., Rodgers, S., Rössler, W.   +5 more
core   +2 more sources

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

FEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro, Marco Cellani, Cristina Scielzo   +2 more
wiley   +1 more source

Screening of mental health and substance users in frequent users of a general Swiss emergency department [PDF]

, 2015
BACKGROUND: The objectives of this study were to determine the proportions of psychiatric and substance use disorders suffered by emergency departments' (EDs') frequent users compared to the mainstream ED population, to evaluate how effectively these ...
Canepa Allen, M., Daeppen, J.B., Hugli, O., Iglesias, K., Paroz, S., Stucki, S.   +5 more
core   +3 more sources

P‐glycoprotein modulates the fluidity gradient of the plasma membrane of multidrug resistant CHO cells

FEBS Letters, EarlyView.
To explore the impact of the overexpression of the multidrug‐transporter P‐glycoprotein (ABCB1) on membrane fluidity, we compared the transversal gradient of mobility and microviscosity in plasma membranes of drug‐sensitive Chinese hamster ovary cells (AuxB1) and their multidrug‐resistant derivatives (B30) using the fluorescent n‐(9‐anthroyloxy) fatty ...
Roger Busche, John R. Riordan, Burkhard Tümmler   +2 more
wiley   +1 more source

Prevalence of Substance Use and Associated Factors Among Secondary School Students in Marrakech Region, Morocco

Psychoactives
Adolescence is a phase characterized by reckless and risky behaviors, including the initiation and use of various illicit substances such as cannabis and alcohol.
Abdelmounaim Baslam, Samia Boussaa, Karima Raoui, Hamid Kabdy, Abdelfatah Aitbaba, Loubna El Yazouli, Rachida Aboufatima, Abderrahman Chait   +7 more
doaj   +1 more source

Overview of substance use disorder and available treatments [PDF]

, 2023
Substance use disorders are a major health problem worldwide. Substance use is a chronic disorder associated with significant mortality and morbidity. These diseases also cause significant healthcare utilization and medical costs. Substance use disorders
Altaf Dar, Mohd, Ara, Irfat, Gani, Imran
core   +1 more source

Evolutionary interplay between viruses and R‐loops

FEBS Letters, EarlyView.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi, Zita Képes, Zoltán Szabó, Eszter Csoma, Lóránt Székvölgyi   +4 more
wiley   +1 more source

Substance use among young people in sub-Saharan Africa: a systematic review and meta-analysis

Frontiers in Psychiatry
BackgroundThe use of substances such as alcohol, tobacco, khat, or drugs among young people is becoming a public health concern globally, with particularly high prevalence rates in low and middle-income settings, where socio-cultural and economic factors
Jemal Ebrahim, Jemal Ebrahim, Jon Adams, Daniel Demant, Daniel Demant   +4 more
doaj   +1 more source

Intensive Case Management for Addiction to promote engagement with care of people with severe mental and substance use disorders: an observational study. [PDF]

, 2017
Co-occurring severe mental and substance use disorders are associated with physical, psychological and social complications such as homelessness and unemployment.
Bonsack, C., Golay, P., Morandi, S., Silva, B.   +3 more
core   +2 more sources