Results 81 to 90 of about 16,081,069 (297)
Indian Journal of Psychiatric Nursing, 2018 Early detection of substance abuse disorders can facilitate treatment. Health care professional's knowledge and attitudes can play a role in the failure to identify and address patients with substance use problems and may negatively influence the care ...
Sumity Arora Tarafdar, Sandhya Gupta
doaj +1 more source
Substance Use Disorders and Schizophrenia
Focus, 2016 Substance use disorders are prevalent co-occurring problems among people with schizophrenia, with lifetime rates approaching 80% in this population when tobacco use is taken into account. Substance use disorders are associated with significant adverse effects among people with schizophrenia, including worse psychiatric symptoms, lower functioning, and ...
Marc, Manseau, Michael, Bogenschutz
openaire +3 more sources
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Personality disorders and substance use disorders: a narrative review
Electronic Physician, 2019 Background: Personality factors have always been considered to play an important role in the etiology of substance-related disorders. Psychopathologic factors underlying an individual's personality structure have a major role in his or her tendency to ...
Farhad Faridhosseini +2 more
doaj +1 more source
Outcome of psychological treatment of patients with substance use disorders in routine care
, 2017 Background: More knowledge is needed about outcome of treatments in routine care for patients with substance use disorders (SUDs). These patients often suffer from psychological distress in addition to SUDs.
Gidhagen, Ylva, +2 more
core +1 more source
, 2023 Rapidly rising drug overdose rates in the United States during the past three decades underscore the critical need to prevent overdose deaths and reduce the development of opioid and related substance use disorders (SUDs).
Latimore, Amanda D +6 more
core +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Determining the primary endpoints for diagnostic test accuracy reviews of substance use disorders
, 2020 Diagnostic test accuracy reviews increasingly are being used in substance use research, yet the majority of the studies considered in these reviews do not account appropriately for the primary endpoints of interest.
Wood, Evan, Dormuth, Colin, Klimas, Jan
core +1 more source