Results 61 to 70 of about 729,288 (289)

Impact of dextroamphetamine substitution on the use of illicit amphetamines in adults with amphetamine dependence: a study protocol for the multicentre double blind randomised controlled trial ATLAS4Dependence

BMJ Open
Introduction There is limited evidence on how to effectively treat individuals from marginalised populations with dependence on amphetamine and/or methamphetamine (collectively referred to hereafter as amphetamine dependence).
, Jörg Assmus, Kjell Arne Johansson, Nicholas Lintzeris, Fatemeh Chalabianloo, Anne Halmøy, Lars T Fadnes, Nadine Ezard, Brendan Clifford, John Fredrik Askjer, Olav Spigset, Torgeir Gilje Lid, Jon Mordal, Else-Marie Løberg, Christina Dahl Andersen, Jan Tore Daltveit, Aleksander H Erga, Kristin K Solli, Minna A K Hansen, Christian Ohldieck, Christer F Aas, Trond Aamo, Tine B Edvardsdal, Siv-Elin L Carlsen, Prayash Chaudhary, Marianne Cook Pierron, Gry I Dale, Silvana De Pirro, Karl Trygve Druckrey-Fiskaan, Zhanna Gaulen, Beate H Trettenes, Minna AK Hansen, Mette H Nordbotn, Line Holtan, Arild Knutsen, Kristin K Solli, Heidi F Kristiansen, Svanhild Mellingen, Maria K Olsvold, Solveig IS Reinertsen, Kristin Sannerud, Krista Siefried, Bente Sikveland, Morten Sommerbakk, Herman Steffensen, Jørn H Vold   +45 more
doaj   +1 more source

Comorbidity of personality disorder among substance use disorder patients: A narrative review

Indian Journal of Psychological Medicine, 2018
Comorbidity of personality disorders (PDs) and substance use disorders (SUDs) is common in clinical practice. Borderline PD and antisocial PD are particularly found to be associated with SUDs.
Arpit Parmar, Gaurishanker Kaloiya
doaj   +1 more source

Comorbidities and Race/Ethnicity Among Adults with Stimulant Use Disorders in Residential Treatment [PDF]

, 2015
Comorbid physical and mental health problems are associated with poorer substance abuse treatment outcomes; however, little is known about these conditions among stimulant abusers at treatment entry.
Carmody, Thomas, Chartier, Karen G., Greer, Tracy L., Rethorst, Chad D., Sanchez, Katherine, Walker, Robrina   +5 more
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Transcranial magnetic stimulation in cocaine use disorder and the risk of seizure: a review of the evidence

Frontiers in Psychiatry
Transcranial magnetic stimulation (TMS) has emerged as a promising intervention for cocaine use disorder (CUD). However, a key concern when employing TMS in CUD is the potential risk of seizures.
Caesar G. Imperio, Caesar G. Imperio, Eric Parmon, Eric Parmon, Vaughn R. Steele, Vaughn R. Steele, Vaughn R. Steele, Derek Blevins, Derek Blevins, Rebecca Chalme, Rebecca Chalme, Jonathan M. Wai, Jonathan M. Wai, Kathleen Brady, Markus Heilig, Colleen A. Hanlon, Colleen A. Hanlon, Frances R. Levin, Frances R. Levin, Diana Martinez, Diana Martinez   +20 more
doaj   +1 more source

Frequency of Parental Psychopathology in Children with Attention Deficit Hyperactivity Disorder [PDF]

, 2012
Parental mental health concerns place children at a significantly greater risk of lower social, psychological and physical health than children in families not affected by mental illness.
Bhat, SM, Latha, KS, Nair, RB
core   +1 more source

Neural mechanisms of affective instability and cognitive control in substance use

, 2019
Objective: We explored the impact of affect on cognitive control as this relates to individual differences in affective instability and substance use.
Bodkyn, Carmen N., Holroyd, Clay
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Suicidal ideation in patients with mental illness and concurrent substance use: analyses of national census data in Norway

BMC Psychiatry, 2022
Background Suicidal ideation may signal potential risk for future suicidal behaviors and death. We examined the prevalence of recent suicidal ideation in patients with mental illness and concurrent substance use and explored the clinical and ...
Helle Wessel Andersson, Solfrid E. Lilleeng, Torleif Ruud, Solveig Osborg Ose   +3 more
doaj   +1 more source