Results 41 to 50 of about 321,265 (263)

Impact of dextroamphetamine substitution on the use of illicit amphetamines in adults with amphetamine dependence: a study protocol for the multicentre double blind randomised controlled trial ATLAS4Dependence

BMJ Open
Introduction There is limited evidence on how to effectively treat individuals from marginalised populations with dependence on amphetamine and/or methamphetamine (collectively referred to hereafter as amphetamine dependence).
, Jörg Assmus, Kjell Arne Johansson, Nicholas Lintzeris, Fatemeh Chalabianloo, Anne Halmøy, Lars T Fadnes, Nadine Ezard, Brendan Clifford, John Fredrik Askjer, Olav Spigset, Torgeir Gilje Lid, Jon Mordal, Else-Marie Løberg, Christina Dahl Andersen, Jan Tore Daltveit, Aleksander H Erga, Kristin K Solli, Minna A K Hansen, Christian Ohldieck, Christer F Aas, Trond Aamo, Tine B Edvardsdal, Siv-Elin L Carlsen, Prayash Chaudhary, Marianne Cook Pierron, Gry I Dale, Silvana De Pirro, Karl Trygve Druckrey-Fiskaan, Zhanna Gaulen, Beate H Trettenes, Minna AK Hansen, Mette H Nordbotn, Line Holtan, Arild Knutsen, Kristin K Solli, Heidi F Kristiansen, Svanhild Mellingen, Maria K Olsvold, Solveig IS Reinertsen, Kristin Sannerud, Krista Siefried, Bente Sikveland, Morten Sommerbakk, Herman Steffensen, Jørn H Vold   +45 more
doaj   +1 more source

Comorbidity of personality disorder among substance use disorder patients: A narrative review

Indian Journal of Psychological Medicine, 2018
Comorbidity of personality disorders (PDs) and substance use disorders (SUDs) is common in clinical practice. Borderline PD and antisocial PD are particularly found to be associated with SUDs.
Arpit Parmar, Gaurishanker Kaloiya
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Substance Use and Substance Use Disorders

Abstract This chapter reviews the DSM-5 definitions for substance use and other addictive disorders, their prevalence in the population, and known genetic, environmental, gene-environment, psychological, and social risk factors. It then examines how religion might influence the development and course of substance use disorders (SUDs ...
Harold G. Koenig, Tyler J. VanderWeele, John R. Peteet   +2 more
  +5 more sources

How to co-create context-sensitive analyses of health service experiences: proposed guidelines for contextualist collaborative thematic analyses with co-researchers

International Journal of Qualitative Studies on Health & Well-Being
Purpose User involvement is a prominent requirement in health services research across international health service contexts. However, current limitations with user-involved analytical approaches restrict researchers' sensitization to service users ...
Nina K. H. Bahl, Morten Brodahl, Hilde E. Nafstad, Rolv M. Blakar   +3 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Transcranial magnetic stimulation in cocaine use disorder and the risk of seizure: a review of the evidence

Frontiers in Psychiatry
Transcranial magnetic stimulation (TMS) has emerged as a promising intervention for cocaine use disorder (CUD). However, a key concern when employing TMS in CUD is the potential risk of seizures.
Caesar G. Imperio, Caesar G. Imperio, Eric Parmon, Eric Parmon, Vaughn R. Steele, Vaughn R. Steele, Vaughn R. Steele, Derek Blevins, Derek Blevins, Rebecca Chalme, Rebecca Chalme, Jonathan M. Wai, Jonathan M. Wai, Kathleen Brady, Markus Heilig, Colleen A. Hanlon, Colleen A. Hanlon, Frances R. Levin, Frances R. Levin, Diana Martinez, Diana Martinez   +20 more
doaj   +1 more source

Disorders Due to Substance Use: Cannabis

, 2023
Cannabis has a long history of use for its psychoactive properties but is a relative newcomer to the Western world as an intoxicant. Nowadays, cannabis is widely used and it causes serious problems in a minority of those who use it. However, given the large numbers of people who use cannabis, that relative minority translates into a substantial ...
Cousijn, J., Compton, W.M., Levin, F.R.
openaire   +5 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Suicidal ideation in patients with mental illness and concurrent substance use: analyses of national census data in Norway

BMC Psychiatry, 2022
Background Suicidal ideation may signal potential risk for future suicidal behaviors and death. We examined the prevalence of recent suicidal ideation in patients with mental illness and concurrent substance use and explored the clinical and ...
Helle Wessel Andersson, Solfrid E. Lilleeng, Torleif Ruud, Solveig Osborg Ose   +3 more
doaj   +1 more source