Results 51 to 60 of about 729,288 (289)

Lifting the Burden of Addiction: Philanthropic Opportunities to Address Substance Use Disorders in the United States [PDF]

open access: yes, 2015
Substance use disorders (SUDs), also known as substance abuse or addiction, affect an estimated 20 million or more adolescents and adults in the U.S. This guidance provides philanthropic funders with the tools & information to reduce immediate harm from ...
Cecily Wallman-Stokes   +6 more
core  

Comorbid mental disorders in substance users from a single catchment area - a clinical study [PDF]

open access: yes, 2011
Background The optimal treatment of patients with substance use disorders (SUDs) requires an awareness of their comorbid mental disorders and vice versa.
Anne-Marit Langås   +2 more
core   +2 more sources

Prevalence and Trajectory of Household Material Hardship Among Children With Advanced Cancer

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background/Objectives Families of children with advanced cancer living in poverty experience inferior outcomes including poor parent mental health and worse child quality of life. Household material hardship (HMH: food, housing, transportation, and/or utility insecurity) is a modifiable poverty exposure—and potential intervention target—that ...
Sarah Wright   +13 more
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Geographic variation in the utilisation of specialist healthcare for patients with substance use disorders in Norway: a population-based registry study

open access: yesResearch in Health Services & Regions
Purpose The purpose of this study is to analyse geographic variation in rates of patients and service utilisation for persons with substance use disorders (SUD) across Norwegian hospital catchment areas from 2017 to 2021, considering both outpatient and ...
Haji Kedir Bedane   +3 more
doaj   +1 more source

Relationship between levels of mindfulness and substance use pattern

open access: yesJornal Brasileiro de Psiquiatria, 2021
Objective Evaluate the association between levels of mindfulness and sociodemographic characteristics and pattern of drug use of individuals seeking treatment in a University Service Specialized in Substance Use Disorders.
Júlia de Souza Baptista   +5 more
doaj   +1 more source

Defining Substance Use Disorders: Do We Really Need More Than Heavy Use? [PDF]

open access: yes, 2017
Aims: The aim of the study was to explore whether the concept of heavy substance use over time can be used as definition of substance use disorder. Methods: Narrative review.
Anderson, P.   +11 more
core  

Externalizing disorders and substance use: empirically derived subtypes in a population-based sample of adults. [PDF]

open access: yes, 2014
PURPOSE: Attention-deficit/hyperactivity disorder (ADHD), conduct disorder (CD), and oppositional defiant disorder (ODD) are common externalizing disorders of childhood. The common effects of these disorders on substance abuse need further investigation.
Ajdacic-Gross, V.   +5 more
core   +2 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Changes in inpatient mental health treatment and related costs before and after flexible assertive community treatment: a naturalistic observational cohort study

open access: yesBMC Psychiatry
Background Flexible Assertive Community Treatment (FACT) is currently implemented in Norwegian mental health services, aiming to ensure comprehensive and rights-based services for persons with severe mental illness and complex needs, but also motivated ...
Eva Brekke   +4 more
doaj   +1 more source

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