Results 141 to 150 of about 107,326 (259)

Valproate-Enhanced Protocols for Alcohol Withdrawal Syndrome: A Brief Review and Retrospective Study of Efficacy and the Ability to Reduce Benzodiazepine Use

Pharmaceuticals
Background: Although benzodiazepines are the first-line treatment for alcohol withdrawal syndrome (AWS), their use may pose significant risks, including oversedation and the potential for misuse, particularly in vulnerable populations such as individuals
Simone Pardossi, Alessandro Cuomo, Giacomo Gualtieri, Mario Pinzi, Giuditta Piumini, Andrea Fagiolini   +5 more
doaj   +1 more source

Calcitonin gene‐related peptide concentration in cerebrospinal fluid and serum in horses affected by trigeminal‐mediated headshaking

Equine Veterinary Journal, EarlyView.
Abstract Background Trigeminal‐mediated headshaking (TMHS) in horses shares clinical features with human trigeminal neuralgia (HTN). Increased levels of the neuropeptide calcitonin gene‐related peptide (CGRP) have been found in the blood and cerebrospinal fluid (CSF) of HTN patients. Inhibition of CGRP in humans has shown promise for pain relief.
Lisa Annabel Weber, Hilke Oltmanns, Ludovica Chiavaccini, Kirstie J. Pickles, Veronica Roberts, Tanja Kloock, Tobias Niebuhr, Karsten Feige   +7 more
wiley   +1 more source

Probiotics Alter the Microbial and Behavioral Consequences of Methamphetamine Exposure in a Sex-Selective Manner

Psychoactives
Methamphetamine use disorder (MuD) is a global health problem, with no FDA-approved medications. Our prior work demonstrated that repeated methamphetamine exposure alters the gut microbiota in male rats and results in depressive-like behaviors.
Shadab Forouzan, Kristi L. Hoffman, Therese A. Kosten   +2 more
doaj   +1 more source

Confronting the opioid crisis: Practical pain management and strategies: AOA 2018 critical issues symposium [PDF]

, 2019
The United States is in the midst of an opioid crisis. Clinicians have been part of the problem because of overprescribing of narcotics for perioperative pain management.
Hsu, Joseph R, Jahangir, A Alex, Miller, Anna N, Mir, Hassan R, Obremskey, William T   +4 more
core   +1 more source

Organ‐sparing strategies in patients with MSI/dMMR tumors including Lynch syndrome: Current state of the art and future perspectives for clinical decision‐making

International Journal of Cancer, EarlyView.
Abstract Deficiency in DNA mismatch repair (dMMR) is a common pathway of carcinogenesis across different tumor types and confers a characteristic microsatellite instability‐high (MSI‐H) molecular phenotype. The MSI‐H/dMMR phenotype may arise from an inherited pathogenic variant in the context of Lynch syndrome and is most frequently observed in ...
Martin Duval, Antoine Dardenne, Thomas Samaille, Leo Mas, Jérémie H. Lefèvre, Xavier Dray, Mathilde Wagner, Romain Cohen, Thierry André   +8 more
wiley   +1 more source

Uncovering the role of genetic polymorphisms in cervical insufficiency

International Journal of Gynecology &Obstetrics, EarlyView.
Pathways and genes implicated in CI pathogenesis. Abstract Cervical insufficiency (CI) is characterized by spontaneous dilation of the cervix in the absence of painful uterine contractions in the mid‐trimester, leading to premature delivery. It is responsible for up to 20% of second trimester pregnancy losses, mostly <24 weeks.
Kallirhoe Kalinderi, Michail Kalinderis, Maria Chatzidimitriou, Liana Fidani   +3 more
wiley   +1 more source

Pharmacological and non-pharmacological treatments for the Neonatal Abstinence Syndrome (NAS). [PDF]

, 2019
Neonatal abstinence syndrome is defined by signs and symptoms of withdrawal that infants develop after intrauterine maternal drug exposure. All infants with documented in utero opioid exposure, or a high pre-test probability of exposure should have ...
Kraft, W. K., Mangat, A. K., Schmölzer, G. M.   +2 more
core   +1 more source

Effectiveness of Trauma‐Focused Cognitive Behavioral Therapy for Treating PTSD and Co‐Occurring Depression: A Meta‐Analytic Update of Experimental Studies

Journal of Counseling &Development, EarlyView.
ABSTRACT The prevalence of co‐occurring posttraumatic stress disorder (PTSD) and depression poses a noteworthy challenge to optimal development and well‐being among youth characterized by variations in risk associated with biological and environmental variables.
A. Stephen Lenz, K. Michelle Hunnicutt Hollenbaugh   +1 more
wiley   +1 more source

Social networking addiction: emerging themes and issues [PDF]

, 2013
Griffiths, MD
core   +1 more source

Profiles of Psychological Capital and Work‐Related Well‐Being Among School Counselors During a Prolonged Emergency

Journal of Counseling &Development, EarlyView.
ABSTRACT School counselors face an elevated risk of burnout due to heavy workloads and sustained stress, particularly during prolonged emergencies. This study examined psychological capital, a positive psychology construct comprising hope, efficacy, resilience, and optimism, as a potential resource for promoting counselors’ work‐related well‐being ...
Yuliya Lipshits‐Braziler, Moshe Tatar, Ina Ben‐Uri, Sima Amram‐Vaknin   +3 more
wiley   +1 more source