Journal of Anesthesia, Analgesia and Critical Care, 2022 We aim to develop evidence-based recommendations for intensivists caring for children admitted to intensive care units and requiring analgesia and sedation.
Angela Amigoni +17 more
doaj +1 more source
Comparing Fixed-amount and Progressive-amount DRO Schedules for Tic Suppression in Youth with Chronic Tic Disorders [PDF]
, 2017 Chronic tic disorders (CTDs) involve motor and/or vocal tics that often cause substantial distress and impairment. Differential reinforcement of other behavior (DRO) schedules of reinforcement produce robust, but incomplete, reductions in tic frequency ...
Capriotti, Matthew R. +4 more
core +1 more source
Clinical psychology of Internet addiction: a review of its conceptualization, prevalence, neuronal processes, and implications for treatment [PDF]
, 2015 Research into Internet addiction (IA) has grown rapidly over the last decade. The topic has generated a great deal of debate, particularly in relation to how IA can be defined conceptually as well as the many methodological limitations.
Griffiths, MD, Kuss, DJ, Pontes, HM
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Determinanten eines vorzeitigen Therapieabbruchs: Über den Einfluss psychosozialer und soziodemographischer Faktoren, externer Ereignisse sowie subjektiver Schlafqualität während der stationären qualifizierten Entzugsbehandlung bei Patienten mit Alkohol- und Drogenabhängigkeit auf den Therapieerfolg [PDF]
, 2020 Introduction Addiction is a chronic disease that affects millions of individuals worldwide. Qualified detoxification treatment is the first step in inpatient substance abuse treatment.
Sofin, Yvonne
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Advanced Science, EarlyView.TREM2 recognizes NETs‐derived MPO to promote DC maturation and antigen presentation, thereby exacerbating the autoimmune response in SLE. Mechanistically, TREM2 activation triggers the DAP12/SYK/ERK cascade and enhances NETs internalization by DCs, which in turn activates the cGAS/STING signaling pathway.
Jingxian Shu +7 more
wiley +1 more source
Effects of Isoniazid on the Acquisition and Expression of Morphine Dependence in Male Mice
Pharmaceutical and Biomedical Research, 2021 Background: GABAergic drugs have extensive interference with morphine’s pharmacological effects, including dependence. Objectives: The present study was conducted to evaluate the effects of isoniazid, a GABAergic agent, on the acquisition and ...
Kamran Shahabi, Amir Abbas Barzegari
doaj
A QUALITY IMPROVEMENT STUDY OF THE implimentation of the VERMONT NEWBORN PLAN OF SAFE CARE AMONG NURSING STAFF AT VERMONT HOSPITALS [PDF]
, 2019 PURPOSE: The purpose of this quality improvement needs assessment was to evaluate the implementation of the Vermont Newborn Plan of Safe Care (VNPSC) since its introduction 17 months ago. These plans were created in response to federal mandates to create
Buley, Annik
core +1 more source
Advanced Science, EarlyView.This study introduces MnSTF, a soft‐drug‐inspired nanoadjuvant that overcomes the systemic toxicity of STING agonists. Through Mn2+ coordination with an ENPP1 inhibitor, it enables safe cGAS‐STING activation, remodels the tumor immune microenvironment, and synergizes with radiotherapy or vaccines to elicit robust antitumor immunity.
Guangfei Sun +8 more
wiley +1 more source
Caffeine. cognitive and physical performance enhancer or psychoactive drug? [PDF]
, 2015 Caffeine use is increasing worldwide. The underlying motivations are mainly concentration and memory enhancement and physical performance improvement. Coffee and caffeine-containing products affect the cardiovascular system, with their positive inotropic
Aromatario, Mariarosaria +3 more
core +1 more source
Advanced Science, EarlyView.Esketamine and ketamine are widely used for perioperative analgesia and anesthesia. Despite their established roles in analgesia, sedation, and anesthesia, as well as emerging antidepressant, anti‐tumor, and anti‐inflammatory effects, their clinical use is limited due to side effects and addiction potential.
Yinxin Wang +7 more
wiley +1 more source