Results 151 to 160 of about 86,799 (302)

Lactoperoxidase is a candidate for mediating neuromelanin formation in the human substantia nigra. [PDF]

Proc Natl Acad Sci U S A
Tóth ZE, Baráth M, Pape VFS, Sípos K, Boros AP, Durst M, Várnai P, Sirokmány G, Geiszt M.   +8 more
europepmc   +1 more source

PREDICT‐PD: A Two‐Stage Approach to Early Identification of Parkinson's Disease

Movement Disorders Clinical Practice, EarlyView.
Sasivimol Virameteekul, Sheena Waters, Brook Huxford, Ashvin Kuri, Manuela Tan, Laura Pérez‐Carbonell, Eduardo de Pablo‐Fernández, Anette Schrag, Alastair J. Noyce, Cristina Simonet   +9 more
wiley   +1 more source

High molecular weight insoluble parkin in the substantia nigra of patients with idiopathic Parkinson's disease. [PDF]

NPJ Parkinsons Dis
Tremblay C, Pshevorskiy L, Cottez RJ, Denis HL, Emond V, Morissette M, Rajput AH, Di Paolo T, Rajput A, Calon F.   +9 more
europepmc   +1 more source

A Brainstem Radiomics Framework to Distinguish Progressive Supranuclear Palsy from Parkinson's Disease

Movement Disorders, EarlyView.
Abstract Background Differentiating progressive supranuclear palsy (PSP) from Parkinson's disease (PD) can be clinically challenging. In the neuroimaging field, radiomics has emerged as a promising approach to capture subtle microstructural and textural image alterations, improving differential diagnoses.
Chiara Camastra, Jolanda Buonocore, Antonio Augimeri, Camilla Calomino, Maria Giovanna Bianco, Alessia Sarica, Pier Paolo Arcuri, Aldo Quattrone, Andrea Quattrone   +8 more
wiley   +1 more source

Motor cortex directly excites the substantia nigra pars reticulata, the basal ganglia output nucleus. [PDF]

Nat Commun
Thompson WS, Wekwejt P, Grillner S, Silberberg G.   +3 more
europepmc   +1 more source

A Schizophrenia‐Spectrum Presentation with Panda Sign: Huntington's Disease Confirmed, Wilson Disease Excluded

Movement Disorders Clinical Practice, EarlyView.
Eva‐Maria Tsapakis, Georgia Zafeiridou, Elizabeth Psoma, Angelos Giannoutsos, Andreas Kiryttopoulos, Konstantinos N. Fountoulakis   +5 more
wiley   +1 more source

Distinct Brain Drivers and Shared Cerebello–Cortical Input in ADCY5 and SGCE Hyperkinetic Movements

Movement Disorders, EarlyView.
Resting‐state fMRI and effective connectivity revealed distinct cerebellar–basal ganglia–cortical interactions in ADCY5 (MxMD‐ADCY5) and SGCE (MYC/DYT‐SGCE) related movement disorders. The cerebellum modulated cortex directly in MYC/DYT‐SGCE, but indirectly via basal ganglia‐cerebellar projections in MxMD‐ADCY5, which also showed reduced subthalamic ...
Clément Tarrano, Cécile Galléa, Asya Ekmen, Cécile Delorme, Eavan M. McGovern, Quentin Salardaine, Lina Daghsen, Manon Gomes, Vanessa Brochard, Eoin Mulroy, Kailash P. Bhatia, Carlo Fusco, Miryam Carecchio, Norbert Brüggemann, Alexander Münchau, Victoria Gonzalez, Diane Doummar, Christine Tranchant, Mathieu Anheim, Philippe Damier, Florence Riant, Mohamed Doulazmi, Agathe Roubertie, Caroline Dubacq, Oriane Trouillard, Romain Valabregue, Mélanie Didier, Benoit Beranger, Pierre Pouget, Marie Vidailhet, Sabine Meunier, Aurélie Méneret, Yulia Worbe, Emmanuel Roze   +33 more
wiley   +1 more source

Striatal dopamine-glutamate interactions reflected in substantia nigra reticulata firing

, 1998
To gain insight into the role of striatal dopamine in basal ganglia functioning, dopaminergic drugs alone and in combination with the glutamate receptor agonist kainic acid were infused in the lateral striatum via a microdialysis probe, while single-unit
Westerink, BHC, Westerhof, F, van der Wal, TIC, Timmerman, W   +3 more
core  

Tissue Effects of the Mitochondrial Division Inhibitor Mdivi-1 on the Substantia Nigra in a Laboratory Model of Dopaminergic System Damage. [PDF]

Int J Mol Sci
Egorova AV, Voronkov DN, Ryabova MS, Stavrovskaya AV, Olshansky AS, Pavlova AK, Baranich TI, Kharlamov DA, Sukhorukov VS.   +8 more
europepmc   +1 more source

Heterogenous Neuropathology in a Pedigree with RAB39B‐Related Parkinson's Disease

Movement Disorders, EarlyView.
Abstract Background In 2015, we reported a family with Parkinson's disease resulting from the RAB39B p.G192R (c.574G>A) variant. Since then, two affected brothers from the family have undergone autopsy. Objectives To characterize neuropathological findings, assess intracellular distribution of RAB39B protein, and examine the effect of p.G192R on α ...
Caitlin Latimer, Oswaldo Lorenzo‐Betancor, Dong‐Hui Chen, Kimmy Su, Marika Bogdani, Anna J. Park, Minsuh Kim, Joshua Weiss, Malia Callier, Ella H. Chiu, Sarah Fish, Jennifer L. Witt, Wendy H. Raskind, Marie Y. Davis, C. Dirk Keene, Cyrus P. Zabetian   +15 more
wiley   +1 more source