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Neurovascular and immune factors of vulnerability of substantia nigra dopaminergic neurons in non-human primates. [PDF]
Balzano T+7 more
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Primary cilia in Parkinson's disease: summative roles in signaling pathways, genes, defective mitochondrial function, and substantia nigra dopaminergic neurons. [PDF]
Tian Z+6 more
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Single-cell sequencing of the substantia nigra reveals microglial activation in a model of MPTP. [PDF]
Liu Q+10 more
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Impact of 6-OHDA injection and microtrauma in the rat <i>substantia nigra</i> on local brain amyloid beta protein concentrations in the affected area. [PDF]
Roldán-Kalil JA+7 more
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Neuromelanin-targeted 18 F-P3BZA PET/MR imaging of the substantia nigra in rhesus macaques.
Feng H+7 more
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Neuromelanin of the Human Substantia Nigra: An Update
Neurotoxicity Research, 2013Dopaminergic neurons of the substantia nigra selectively degenerate over the course of Parkinson's disease. These neurons are also the most heavily pigmented cells of the brain, accumulating the dark pigment neuromelanin over a lifetime. The massive presence of neuromelanin in these brain areas has long been suspected as a key factor involved in the ...
Zucca FA+6 more
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