Results 271 to 280 of about 134,010 (347)
Increased Numbers of CD4+ T‐Cells in the Hypocretin/Orexin Region of Narcolepsy Type 1
Narcolepsy type 1 (NT1) is presumed to be an autoimmune disorder caused by hypothalamic loss of hypocretin (Hcrt; orexin). In postmortem NT1 brains, we observed an 11‐fold increase of CD4+ T‐cells in the Hcrt region compared with control hypothalami, without a corresponding rise in CD8+ T‐cells.
Ling Shan +5 more
wiley +1 more source
Nanomaterial‐Mediated Near‐Infrared Photothermal Neuromodulation for Neurologic Disorders
This review summarizes how near‐infrared light activates photothermal nanomaterials to enable noninvasive neuromodulation with high spatiotemporal precision. It elucidates the underlying mechanisms, explores targeted therapeutic applications for neurological disorders, discusses integration with optogenetics and biosensors, and addresses future ...
Ting‐Ting Zeng +9 more
wiley +1 more source
Unraveling the complexity of neurodegeneration: heterogeneous damage patterns of locus coeruleus and substantia nigra in Alzheimer's disease. [PDF]
Tang C +6 more
europepmc +1 more source
Among 148 older patients with Parkinson's disease, lower MoCA scores were independently associated with higher odds of sarcopenia, while higher HAMA scores were also associated with sarcopenia. Cognitive assessment may help screen for sarcopenia risk in this population. ABSTRACT Purpose This study aimed to investigate the association between sarcopenia
Qiuwan Liu +6 more
wiley +1 more source
Localization of Melanocortin 1 Receptor in the Substantia Nigra. [PDF]
Ehara A, Ito N, Nakadate K, Tokuda N.
europepmc +1 more source
Schematic summary of visual electrophysiology and retinal and brain pathology. The diagram integrates PVEP abnormalities, retinal pathology, and brain pathology in PFF‐injected mice. Based on behavioral outcomes, the three groups were categorized as control, prodromal PD, and PD, corresponding to the PBS, 3‐month PFF (3 MPI), and 6‐month PFF (6 MPI ...
Qin Zhang +7 more
wiley +1 more source
Substantia nigra modulates breathing rate via locus coeruleus. [PDF]
Gu BM +4 more
europepmc +1 more source

