Results 281 to 290 of about 132,532 (337)

A deep cellular atlas of the human ventral substantia nigra in Parkinson’s identifies a genetic and molecular overlap with insulin resistance

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Substantia Nigra Involvement

Neurology, 2021
A 20-year-old man without medical history but with septic shock developed neuroleptic malignant syndrome after being treated with loxapine for delirium. He had been admitted to the intensive care unit 2 weeks earlier for septic shock. An MRI done 27 days after admission for persistent unresponsiveness despite weaning of sedation revealed symmetric and ...
François Lersy, Hamid Merdji
openaire   +2 more sources

Substantia Nigra Hyperactivity in Schizophrenia

Biological Psychiatry, 2013
Mapping the clinical features of schizophrenia to circuits in the brain is a major goal for schizophrenia researchers. The prefrontal cortex (PFC), the ventral midbrain, and the striatum are among the brain areas of primary interest. The PFC has been linked to cognitive deficits, especially impairment of working memory.
Stephan, Heckers, Christine, Konradi
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Dopamine release in substantia nigra?

Nature, 1976
IN addition to the axons which project to the nucleus caudatus1,2, the dopamine (DA)-containing perikarya of the substantia nigra have extensive dendritic processes. These dendrites, observed after Golgi staining3–5 and by electron microscopy3,4, contain relatively large amounts of DA—revealed by histofluorescence6—and vesicle–like structures4.
KORF, J, ZIELEMAN, M, WESTERINK, BHC
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Substantia Nigra and Parkinsonism

Archives of Neurology, 1964
The opinion that parkinsonism is caused by damage of the substantia nigra was advanced by Brissaud 1 on the basis of the findings in a case of Charcot's studied by Bechet 2 and Blocq and Marinesco. 3 In a series of 54 autopsies Tretiakoff 4 found the substantia nigra degenerated in 16 categories of neurologic disorder including three cases of ...
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Diagnostic evaluation of the substantia nigra

Neuropathology and Applied Neurobiology, 1996
An improved method for the histopathological evaluation of the substantia nigra for diagnostic purposes is proposed. This method takes advantage of the natural architecture of the constituent cell clusters of the substantia nigra by combining standardized sections in the horizontal plane and simple quantification. The use of this standardized technique
D A, McRitchie   +2 more
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