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Caspases and their substrates [PDF]
Protease biology is intimately linked to the functional consequences of substrate cleavage events. Human caspases are a family of 12 fate-determining cysteine proteases that are best known for driving cell death, either apoptosis or pyroptosis. More recently, caspases have been shown to be involved in other cellular remodeling events as well including ...
Olivier Julien, James A Wells
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IntroductionHeart disease is a major cause of mortality in aging dogs and cats, with cardiomegaly being the most frequent radiographic finding. While deep learning methods have shown potential in detecting and quantifying cardiomegaly, their integration ...
Habtamu Tilahun Mekonnen +13 more
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The discovery of prolyl hydroxylase domain proteins (PHDs) as key enzymes in the hypoxia inducible factor (HIF) pathway has been followed by reports of a multitude of non-HIF substrates of PHD. Reporting in eLife, Cockman et al. (2019) find a surprising lack of detectable PHD activity toward any of them.
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In humans, fatty acid elongase 7 (ELOVL7) plays a role in synthesis of long-chain saturated fatty acids. Whether ELOVL7 protein plays a role in ruminants is unclear.
Hengbo Shi +5 more
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This research aimed at improving the fatty acid (FA) profile of Hermetia illucens larvae (HI) and evaluating the effects of their inclusion in growing broiler quails’ diets on the meat physicochemical quality, including detailed amino acid (AA) and
Marco Cullere +5 more
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Modelling pyroclastic density currents (PDCs) is a challenging yet essential element of hazard assessment. PDCs are unpredictable and internal processes are often difficult to measure directly.
Nemi Walding +5 more
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Glucose Tolerance of Clostridium acetobutylicum Fermentation in the Anaerobic System
Solvent-producing Clostridium acetobutylicum was purified and used in an acetone-butanol-ethanol (ABE) fermentation process. The objective of this study is to design a fermentation medium for the synthesis of butanol and determine the ideal glucose ...
Basirah Fauzi +7 more
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BROADBAND SUBSTRATE TO SUBSTRATE INTERCONNECTION
A broadband substrate to substrate microwave circuit interconnection is proposed using bond wires and defected ground structure (DGS). The proposed square-shaped DGS etched under compensated microstrip open stubs not only expands its operating bandwidth, but also increases the characteristic impedance of microstrip line without narrowing its width ...
Bo Zhou +4 more
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The Transmission of Substrate Features
Theories of the formation of creole syntax have been proposed to explain whether substrates and superstrates influence the resultant creole structures, and if so, what the mechanisms are by which they influence them.
Robert Laub
doaj
Atrial fibrillation: A never ending story?
Atrial fibrillation (AF) often recurs after ablative therapy. In our patient, intraoperative epicardial mapping during therapy‐ resistant AF revealed highly dissociated atrial conduction patterns and that long lines of conduction block throughout the ...
Eva A. H. Lanters +3 more
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