Results 51 to 60 of about 3,502,500 (295)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Strain engineered graphene using a nanostructured substrate: I Deformations

open access: yes, 2012
Using atomistic simulations we investigate the morphological properties of graphene deposited on top of a nanostructured substrate. Sinusoidally corrugated surfaces, steps, elongated trenches, one dimensional and cubic barriers, spherical bubbles ...
D. Nelson   +4 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

AGROTECHNOLOGУ OF SMALL-VOLUME AND NON-SOIL INTENSE LIGHT-CULTURE IN CUCUMBER

open access: yesОвощи России, 2017
Technology  of  intense  light-culture   has  been  developed to grow different crops under controlled environmental conditions  with  the use of specialized vegetation  apparatus  (VSU). In  the  specialized  vegetation apparatus,  designed  to   grow  
L. M. Anikina   +4 more
doaj   +1 more source

Evaluating a Controlled-Release Fertilizer for Plant Establishment in Floating Elements for Bioretention Ponds

open access: yesAgronomy, 2020
In bioretention ponds proposed to manage urban runoff, floating elements with anchored macrophytes plants improve nutrient and pollutants removal and provide aesthetic benefits.
Giampaolo Zanin   +4 more
doaj   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Deep learning framework for vertebral heart size and cardiothoracic ratio estimation in dogs and cats using thoracic radiographs

open access: yesFrontiers in Veterinary Science
IntroductionHeart disease is a major cause of mortality in aging dogs and cats, with cardiomegaly being the most frequent radiographic finding. While deep learning methods have shown potential in detecting and quantifying cardiomegaly, their integration ...
Habtamu Tilahun Mekonnen   +13 more
doaj   +1 more source

Light intensity strain analysis [PDF]

open access: yes, 1973
A process is described for the analysis of the strain field of structures subjected to large deformations involving a low modulus substrate having a high modulus, relatively thin coating.
Williams, J. G.
core   +1 more source

Critical Casimir interaction of ellipsoidal colloids with a planar wall

open access: yes, 2009
Based on renormalization group concepts and explicit mean field calculations we study the universal contribution to the effective force and torque acting on an ellipsoidal colloidal particle which is dissolved in a critical fluid and is close to a ...
Casimir H. B. G.   +7 more
core   +1 more source

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